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The effects of phytoestrogen isoflavones on bone density in women:a double-blind, randomized, placebo-controlled trial1–3 Charlotte Atkinson, Juliet E Compston, Nicholas E Day, Mitch Dowsett, and Sheila A Bingham ABSTRACT for their potential bone-sparing properties. Rates of hip fracture Background: Isoflavone phytoestrogen therapy has been pro- in Asian populations, whose traditional