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Cell biology

University of Salahaddin
College of Science
Department of Biology

Dr. Hero Mohammad Ismael
Academic year: 2011-2012
Course objective:
The course will cover Microbial Physiology texts topics with print media and
internet articles including schematic diagrams, images and movies that deal
with the field of microbial physiology that expanded at an incredibly rapid
pace since the last edition of this text. To give full measure to the
extraordinary advances made in microbial physiology. The development and
implementation of new, highly sophisticated, techniques to study the
molecular genetics and physiology of an ever broadening range of microbes
has prompted to study this field of the science. The lectures consider with the
bacterial structures, microbial growth, nutrition requirements, the factors that
affecting growth, micro and macronutrient, enzymes and the metabolism
pathways of the microorganism, intermediary metabolism; also deals with
antibiotics and toxins production by these microbes. One of the benefits of
students taking Microbial Physiology course is that they will become more
familiar with the microbial metabolism, and to better appreciate the elegant
simplicities and the intricate complexities of microbial physiology, while at
the same time realizing that there is still much to be learned.
Forms of Teaching:
Different forms of teaching will be used to reach objectives of the course:
power point presentations for the head titles and definitions and summary of
conclusions, metabolisms pathway. The lectures content will be in English
language, in addition to discussions and clearing in English, Arabic and
Kurdish language if necessary, the lecture will give enough background to
translate, solve, and analyze problems sets and different issues discussed
throughout the course.
The students are required to do two closed book exams during the academic
course, beside the attendance, classroom activities count 25 marks, and
there will be final examination on 60 marks as the followings:
Mean of three examination 25%
Practical examination 15%
Final examination 60%
Course material
1- A. G. Moat, J. W. Foster, and M. P. Spector (2002). Microbial
Physiology, 4th edition.
2- D. H. Griffin (1981). Fungal Physiology.
3- G. N. Cohen (2011). Microbial Biochemistry. 2nd Edition, Springer
4- T. D. Brock (1990). Biology of Microorganisms, 2nd edition, prentice-
5- G. C. Ainsworth and A. S. Sussman (1969). The Fungi (The Fungal
Cell), Academic Press
6- D. T. Wicklow and B. E. Soderstrom (1997). The Mycota
(Environmental and Microbial Relationships). Springer.
7- L. M. Prescott, J. P. Harley and D. A. Klein (2005). Microbiogy, 6th
8- R. W. Bauman (2007). Microbiology with diseases by Taxonomy, 2nd
Introduction, course outline of the Science of Microbial PhysiologyMicrobial GrowthGrowth curve Week 2:Factors affecting growthChemical factors:FungicidesAntibioticsPhysical factors:TemperatureOsmotic pressurepHRadiationCO2 Week 3:Nutritional requirementsMacronutrientCarbon, Nitrogen, Phosphorus,, Sulfur, Potassium, MagnesiumMicronutrientCopper, Iron, Manganese, Zinc, Molybdenum Week 4:Transport of solutesPassive diffusionFacilitated diffusionActive transport and co-transportGroup translocation Week 5:Microbial metabolismEmbden-Meyerhof-Parnas (EMP) pathwayHomofermentative organismHeterofermentative organismRespirationThe Tricarboxylic acid cycle (TCA)The Respiratory chain Week 6:Entner- Duodoroff (ED) PathwayPhosphoketolase Pathway (Warburg-Dickens- Horecker)Pentose Phosphate Pathway (PPP) Week 8:Energetic of biosynthesisGluconeogenesisMetabolism of AutotrophsChemolithitrophyPhotoautotrophy Week 9:Fungal toxinsToxins drived from aminoacidsErgotamine, Lysergic acid and Ergot alkaloidAromatic and Phenolic toxinsAflatoxinsTrichothecens Week 10:Bacterial toxinsExotoxinsEndotoxins Week 11:Mechanism of survival:SporulationEndospores and mutationsSpore dormancy, activation and germination Week 12:Interaction between organismsNeutralismCommensalismMutualismSynergismCompetitionParasitism Week 13:Microbial pathogenisityBacterial virulent factorsFungal virulent factors


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