Dr. Harish Padh
Department of Cell and Molecular Biology, B.V. Patel Pharmaceutical
Education and Research Development (PERD) Centre, Sarkhej
Gandhinagar Highway, Thaltej, Ahmedabad-380054
Email: hpadh@yahoo.com Current position: Vice Chancellor, Sardar Patel University, Vallabh Vidyanagar, Gujarat and Advisor in B.V.Patel PERD centre andNIPER - Ahmedabad
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Previous positions: Project Director: NIPER-Ahmedabad (2007-2010) Director: B.V. Patel PERD centre, Ahmedabad (1999-2010)
Visiting Faculty: University of North Carolina, Chapel Hill, North Carolina, USA (2006 May-Oct)
Professor: M.S. University of Baroda, Vadodara, INDIA (1996-2001)
Assistant Director and Associate Professor: Northwestern University, Center for Biotechnology, Evanston, IL. USA (1993-95)
Assistant Professor-Research: University of Chicago, Department of Biochemistry & Molecular Biology (Jan 1987-sep 1992)
Associate Professor-Research: University of Chicago, Department of Biochemistry & Molecular Biology (Oct 1992-Apr 1993)
Research Associate: Temple University Health Sciences Center, Philadelphia (Jan 1981-Dec 1983)
Research Assistant Professor: Temple University Health Sciences Center, Philadelphia (Jan1984-Dec 1986)
Leon Journey Fellow: St. Jude Children’s Research Hospital, Memphis, TN (1979-1980)
Lecturer: S. P. University, Department of Biosciences, Vallabh Vidyanagar, India
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Education:
¾ Ph.D. (Biochemistry): University of Delhi in 1978.
¾ M. Sc. (Biochemistry)–M. S. University Baroda, 1973.
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Research areas: Cell and Molecular Biology, Biotechnology, Pharmacogenetics, Drug Delivery
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Publications:
Number of research papers and reviews published: Over 130+
Number of additional abstracts and presentations: over 200+ Total citation: 1883: H-index: 22; i10 Index: 46 List of Publications
Padh H., Aduda B.O. and de Alwis A. P. Editors. Nanotechnology : Present Status and Future Prospects in Developing Countries. ISBN : 9788170357070. 2011, NAM S&T Center, New Delhi. Daya Publishing House. Research Publications In three sections: (Impact Factors for few publications listed as IF)
• Pharmaceuticals Sciences • Cell, Molecular Biology and Biotechnology Related
• General List of Publications – Related to Pharmaceutical Sciences
D. N. Azmanov, S Dimitrova, L. Florez, S. Cherninkova, D. Draganov, B. Morar, R. Saat, M. Juan, J. I Arostegui, S. Ganguly, H. Soodyall, S. Chakrabarti, Harish Padh, M. A Lo´pez-Nevot, V. Chernodrinska, B. Anguelov, P. Majumder, L. Angelova, R. Kaneva, D. A. Mackey, I. Tournev and L. Kalaydjieva. LTBP2 and CYP1B1 mutations and associated ocular phenotypes in the Roma/Gypsy founder population. European Journal of Human Genetics19, 326–333, 2011 [IF 3.6]
Shep, D., Ojha, A., Patel, S., Nivsarkar, M, Jaiswal, V and Padh H. Comparative bioavailability study of a new formulation of injection of 75 mg. Diclofenac Sodium in 1 ml. with the conventional injection of 75 mg. Diclofenac Sodium given in 3 ml. volume. Current Clinical Pharmacology, 6(1), 26 – 29, 2011. [IF 2.8]
Desai, P., Shrivastava, N., and Harish Padh. Production of heterologous proteins in plants: Strategies for optimal expression. Biotechnology Advances 28, 427- 435, 2010. [IF 8.25]
Shep, D., Ojha, A., Patel, S., Nivsarkar, M, Jaiswal, V and Padh H. Pharmacokinetic profile of a new formulation of injection diclofenace in Indian volunteers with BMI> 25. J. Pain Research, 3, 235 – 240, 2010.
Shep, D., Ojha, A., Patel, S., Nivsarkar, M, Jaiswal, V and Padh H. Bioequivalence and Pharmacokinetic evaluation of two formulations of paracetamol ER 650 mg: A single dose randomized two period crossover comparison in healthy Indian adult volunteers. International Journal of Current Pharmaceutical Research, 2(4), 28 – 31, 2010.
SG, Banerjee A, Chauhan BF, Padh H, Nivsarkar M, Mehta AA.
Inhibitory effect of n-butanol fraction of Moringa oleifera Lam. seeds on ovalbumin-induced airway inflammation in a guinea pig model of asthma.Int. J. Toxicol. 28(6):519-27 2009.[IF 1.267]
Hitesh Vaidya, Mandapati Rajani, Vasudevan Sudarsanam, Harish Padh, Ramesh Goyal. Swertiamarin: A lead from Enicostemma littorale Blume for anti- hyperlipidaemic effect. European Journal of Pharmacology, 617, 108 – 112, 2009. [IF 2.787]
Ashwini Ojha, Rajeshwari Rathod and Harish Padh. Simultaneous HPLC-UV determination of rhein and aceclofenac in human plasma. Journal of Chromatography B, 877, 1145 – 1148, 2009. [IF 2.5]
Ashwini Ojha, Dhaneshwar Shep, Manish Nivsarkar, sweta Patel, Vijayajaiswal and Harish Padh. Pharmacokinetic profile of a new formulation of injection diclofenac designed for intradeltoid use. Expert Opinion on Pharmacotherapy, Vol.10 (4) 517 – 522, 2009. [IF 2.077]
Aryamitra Banerjee, arish Padh and Manish Nivsarkar. Role of the calcium channel in blastocyst implantation: A novel contraceptive target. Journal of Basic & Clinical Physiology & Pharmacology, Vol. 20 (1) 43 – 53, 2009. [IF 0.54]
Manish Nivsarkar, Aryamitra Banerjee, Harish Padh. Cyclooxygenase inhibitors: a novel direction for Alzheimer’s management. Pharmacological Report, 60, 692 – 698, 2008. [IF 2.167]
Rajeshwari Rathod, L. Poorna Chandra Prasad, Shubha Rani, Manish Nivsarkar, Harish Padh. Estimation of Carvedilol in human plasma by using HPLC- fluorescence detector and its application to pharmacokinetic study. Journal of Chromatography B, 857, 219-223, 2007. [IF 2.5]
Chaula Patel, Minal Patel, Shubha Rani, Manish Nivsarkar, Harish Padh. A new high performance liquid chromatographic method for quantification of atomoxetine in human plasma and its application for pharmacokinetic study. Journal of Chromatography B, 850, 356 - 360, 2007. [IF 2.5]
Prashanth Kumar, Neelam S. Chauhan, Harish Padh, M. Rajani. Search for antibacterial and antifungal agents from selected Indian medicinal plants. Journal of Ethnopharmacology, 107, 182 - 188, 2006. [IF 2.26]
Ajay. D Pillai,Shubha Rani, Parendu. D Rathod, Franklin. P Xavier, Harish Padh, Vasudevan Sudarsanam and Kamala. K Vasu. Tetra substituted thiophenes as anti-inflammatory agents: Exploitation of analogue-based drug design. Bioorganic & Medicinal Chemistry, 13, 6685-6692, 2005. [IF 3.075]
Bhupendrasinh Chauhan, Shubha Rani, Swati Guttikar, Anjali Zope, Nimisha Jadon, Harish Padh. Analytical method development and validation of mianserin hydrochloride and its metabolite in human plasma by LC-MS. Journal of Chromatography B, 823, 69-74, 2005. [IF 2.5]
Ajay. D Pillai,Shubha Rani, Parendu. D Rathod, Franklin. P Xavier, Kamala. K Vasu,Harish Padh and Vasudevan Sudarsanam.Q.S.A.R Studies on Some Thiophene Analogs as Anti-inflammatory Agents: Enhancement of Activity by
Electronic Parameters and its Utilization for Chemical Lead Optimization. Bioorganic & Medicinal Chemistry, 13, 1275-1283, 2005. [IF 3.075]
Milind Bagul, H. Srinivasa, Harish Padh and M. Rajani. A rapid densitometric method for simultaneous quantification of gallic acid and ellagic acid in herbal raw materials using HPTLC. J. Sep. Sci., 28, 581-584, 2005. [IF 2.746]
Patel M., Cherian B., Padh H., and Nivsarkar Manish. Olanzepine induced thrombocythemia in Spargue-Daley rats. Drug Chemical and Toxicology 27(4), 379 - 387, 2004. [IF 1.409]
Shubha Rani, Swati Guttikar, Rajeshwari Rathod, Bapu Cherian, Manish Nivsarkar and Harish Padh. Determination of oral Meloxicam pharmacokinetic parameters in Asian Indians: Comparison with a German population. Saudi Pharmaceutical Journal, 12 (4), 144 - 149, 2004.
B. Pathak, K. Niranjan, H. Padh, M. Rajani. TLC densitometric method for the quantification of Eugenol and Gallic acid in Clove. Chromatographia, 60, 241 - 244, 2004. [IF 1.312]
Srinivasa, Milind S. Bagul, Harish Padh, Rajani M. A rapid densitometric method for the quantification of luteolin in medicinal plants using HPTLC. Chromatographia, 60, 131-134, 2004. [IF 1.312]
Ajay D. Pillai, Parendu D. Rathod, P.X Franklin., Harish Padh, Kamala K. Vasu, and V. Sudarsanam. Design, synthesis, and SAR studies of some 5-aliphatic oximino esters of thiophene as potential anti-inflammatory leads: Comparative biological activity profile of aliphatic oximes vs aromatic oximes. Biochemical and Biophysical Research Communications, 317, 1067-1074, 2004. [IF 2.648]
Ajay D. Pillai, P. D. Rathod, P. X. Franklin, M. Patel, M. Nivsarkar, K. K. Vasu, Harish Padh, and V. Sudersanam. Novel drug designing approach for dual inhibitors as anti-inflammatory agents: implication of pyridine template. Biochem Biophys Res Commun. 301(1):183-186, 2003. [IF 2.648]
Rajani M., Saxena N., Ravishankara MN., and Padh H. Evaluation of antimicrobial activity of Ammoniacum gum from Dorema ammoniacum D. Don. Pharmaceutical Biology. 40(7):534-541, 2002. [IF 0.488]
Ravishankara M.N., Neeta Shrivastava, Harish Padh and Rajani M. Evaluation of antioxidant properties of root bark of Hemidesmus indicus. Phytomedicine. 9(2),:153 - 161, 2002. [IF 2.330]
Ravishankara M.N., Neeta Shrivastava, Harish Padh and Rajani M. Evaluation of antioxidant properties of root bark of Hemidesmus indicus. Phytomedicine. 9(2),:153 - 161, 2002. [IF2.330]
Ravishankara M.N., Neeta Shrivastava, Harish Padh and Rajani M. HPTLC method for the estimation of alkaloids from Cinchona officinalis stem bark and its formulations. Planta Medica 67(3), 294-296, 2001. [IF 1.960]
Ravishankara M.N., Neeta Shrivastava, Padh H. and Rajani M. Sensitive high performance thin layer chromatography method for the estimation of diospyrin, antitumor inhibitory agent from stem bark of Diospyrus montana Roxb. Journal of Chromatography B. 744:257 - 262, 2000. [IF 2.5]
Padh, H. and Venkitasubramanian, T. A. Use of enzymes as medicines. J. Health Sciences: Arogya 1: 101-105, 1975. [IF 0.654]
P. X. Franklin, S.Yerande, H. M. Thakar, G. S. Inamdar, R. S. Giri, H. Padh, V. Sudarsanam and Kamala K. Vasu. Synthesis, antiinflammatory and HIV-1
integrase inhibitory activities of 1, 2-Bis[5-thiazolyl] ethane-1, 2-dione derivatives. Indian J. Pharm. Sci., 71 (3), 259 – 263, 2009.
AsthaVarma, Harish Padh and Neeta Shrivastava. Andrographolide: A New Plant-Derived Antineoplastic Entity on Horizon. eCAM 2009, doi:10.1093/ecam/nep135.
Aryamitra Banerjee, Harish Padh and Manish Nivsarkar. Role of the calcium channel in blastocyst implantation: A novel contraceptive target. Journal of Basic & Clinical Physiology & Pharmacology, Vol. 20 (1) 43 – 53, 2009.
Shubha Rani, Gurmeet Singh, Aryamitra Banerjee, Manish Nivsarkar and Harish Padh. Single and Multiple dose toxicokinetics of Rofecoxib in Sprague Dawley Rats : Implication of drug accumulation and sex differences. Adv. Pharmacol Toxicol. 9 (1), 1 – 7, 2008.
Shubha Rani, Aryamitra Banerjee, Manish Nivsarkar, Gurmeet Singh, Minal Patel and Harish Padh. Serial and sparse sampling approaches in single and multiple dose toxicokinetic studies: A comparison. Int. J. Pharmacol. Biol. Sci. 2 (1) 71 – 78, 2008.
Ojha Ashwini, Guttikar Swati, Vayeda Chintan, Padh Harish. Determination of Pitavastatin from human plasma using High Performance Liquid Chromatography with Flourescence Detection. Chinese Journal of Chromatography, 25 (5), 715-718, 2007.
Ashwini Ojha, Rajeshwari Rathod, Chaula Patel, Harish Padh. LC-MS Determination of Gabapentin from Human Plasma. Journal of Chromatographia, 2007. [IF 1.1]
Neelam Chauhan, Shubha Rani, H. Padh. Pharmacogenetics: Genetic Basis for Rational Drug Therapy. Indian Journal of Pharmaceutical Sciences, 69(2), 180 -189, 2007. [IF 0.72]
Anti-hyperlipidemic effect of Carica Papaya in sprague dawley rats. Aryamitra Banerjjee, Rakesh Vaghasiya, Neeta Shri vastava, Harish Padh and Manish Nivsarkar. Nig. J. Nat. Prod. And Med. 10, 69 - 72, 2006.
Shubha Rani and Harish Padh. Inter-Individual Variation in Pharmacokinetics of Proton Pump Inhibitors in Healthy Indian Males. Indian Journal of Pharmaceutical Sciences, 68(6), 754 - 759, 2006.
Shubha Rani, Monica Verma, Shivaprakash and Harish Padh. Formulations dependent variability in the pharmacokinetics: A case study with Metformin. W. J. Med. Sci., 1(1), 9 - 13, 2006.
Shubha Rani, Swati Guttikar, Anjali Zope, Rajeshwari Rathod, Manish Nivsarkar and Harish Padh. Zafirlukast pharmacokinetics in healthy Indian male subjects: Possibility of interethnic variability. Indian J. Allergy Asthma Immunol. 19(2), 69 -73, 2006.
Chauhan B., Rani S., Nivsarkar M. and Padh H. A new liquid-liquid extraction method for determination of Montelukast in small volume human plasma samples using HPLC with Fluorescence Detector. Ind. J. Pharma. Sci., 68(4), 517 - 520, 2006.
Manish Nivsarkar, Aryamitra Banerjee, Deval Shah, Jaimic Trivedi, Manoj Patel, Bapu Cherian and Harish Padh. Reduction in aluminum induced oxidative stress by Meloxicam in rat brain. Iranian Biomedical Journal, 10(3), 151-155, 2006.
Shubha Rani, M. Nivsarkar, Rajeshwari Rathod, Swati Guttikar and H. Padh. Bioequivalence of Fenofibrate tablet formulations in healthy Indian male subjects. Indian J. Pharm. Sci., 67(3) 297 - 301, 2005.
A. Banerjee, N. Shrivastava, A. Kothari, H. Padh and M. Nivsarkar. Antiulcer activity of methanol extract of Eclipta alba. Indian J. of Pharm. Sci., 67(2) 165 - 168, 2005.
Nivsarkar Manish, Patel M., Padh H., Cherian B. And Shrivastava N. Blastocyst implantation failure in mice due to “non receptive endometrium” endometrial alterations by Hibiscus rosa sinnensis leaf extract. Contraception 71 (3), 227- 230, 2005. [IF 2.37]
Cherian B., Rathod R., Guttikar S., Nivsarkar M., Shubha Rani and Padh H. A rapid, selective and sensitive method for extraction and analysis of Celecoxib in human plasma. Indian Drugs, 41(4): 221 - 225, 2004.
Shubha Rani and Harish Padh. Evaluation of truncated area under the curve and truncated area under the curve with limited blood samples in bioequivalence studies. Indian J. Pharm. Sci., 65(4): 371 - 377, 2003.
Prashanthkumar V., Ravishankara M.N., Bagul M., Padh H., Rajani M. High performance thin layer chromatographic method for the estimation of rutin from medicinal plants. Journal of Planar Chromatography - Modern TLC, 16, 386-389, 2003. [IF 1.15]
Padh H. Pharmacokinetics:Chemical v/s protein therapeutics. Indian Drugs. 40(8):437 - 449, 2003.
Milind S. Bagul, Ravishankara M.N., Harish Padh and Rajani M. Phytochemical evaluation and free radical scavenging properties of rhizome of Bergenia ciliata (Haw) sternb. Forma ligulata Yeo. J. Natural Remedies. 3: 83-87, 2003.
Ravishankara M.N., Neeta Shrivastava, Harish Padh and Rajani M. Antioxidant activity of Cinchona officinalis stem bark extracts. Oriental Pharmacy and Experimental Medicine, 3(4), 205-211, 2003.
Nivsarkar M., Rathod P., Vasu K., Zope A., Sudarsanam V., Bapu C. And Padh H. Altered glucose tolerence by a Guanidinothiorea compound in Sprague Dawley Rats: Possible mechanism(s) for Hyperglycemia. Indian Drugs, 41(5): 294 - 297, 2004.
55. Niranjan K, Ravishankara M.N., Harish Padh and Rajani M. A new
spectrophotometric method for the estimation of total alkaloids in the stem bark and seed of Holarrhena antidysenterica (Linn.) Wall and in the Ayurvedic formulation Kutajarishta. Journal of Natural Remedies. 2(2): 2002.
Shubha Rani, Guttikar Swati, Zope Anjali, Cherian Bapu, Nivsarkar Manish and Padh Harish. Pharmacokinetics of olanzapine in Asian Indians and comparison with other populations: Possibility of population diversity. Indian Drugs. 39(11):583 -588, 2002.
Ravishankara M.N., Neeta Shrivastava., Harish Padh and Rajani M. A simple spectrophotometric method for the estimation of total alkaloids from seed of Lupinus albus L. Indian Drugs. 39(9):494 - 496, 2002.
Nivsarkar M., Mukherjee M., Patel M., Padh H and Bapu C. Launaea nudicaulis leaf juice exhibits antiinflammatory action on acute and chronic inflammation models in rats. Indian Drugs. 39(5):290 - 292, 2002.
Rajani M, Ravishankara M.N., Neeta Shrivastava and Harish Padh. HPTLC aided phytochemical fingerprinting analysis as a tool for evaluation of herbal drugs. A case study of Ushaq (Ammoniacum gum). J. Planar Chromatogr. 14(1), 34-41, 2001. [IF 1.15]
Nivsarkar M., P. De, K.B. Patel, A. Katewa, H. Padh and C. Bapu. Subacute toxicity of COX-2 anti-inflammatory agent in mice. Advances in Pharmacology and Toxicology. 2(2) 29-34, 2001.
Manish Nivsarkar and Harish Padh. Pulse of Indian Pharmaceutical Sector - Issues and opportunities. Indian Pharma Industry: Issues and Options, Saket Publications. pp 37-53, 2001
Ravishankara M.N., Neeta Shrivastava, Harish Padh and Rajani M. Simultaneous determination of four alkaloids of Cinchona officinalis from the stem bark and formulations containing Cinchona by HPLC methods. Indian Drugs 38(5):248 - 253, 2001.
Ravishankara M.N., Neeta Shrivastava, Mahendru N., Harish Padh and Rajani M. Simple colourimetric method for the estimation of alkaloids from Cinchona officinalis stem bark and its formulations. Indian J. Pharm. Sci. 63(1):76 - 78, 2001.
Bapu, P. De, K.B. Patel, A. Katewa, M. Nivsarkar and H. Padh. Sub-acute toxicity of COX-2 anti-inflammatory agent in rat. Ind. J. Toxicol. 8(2) 163-168, 2001.
Shubha Rani and Harish Padh. Sparse sampling approach in rodent preclinical pharmacokinetic studies to reduce the use of animals. Ind. J. Pharmacol., 33(3), 192, 2001.
Shubha Rani and Harish Padh. Estimation of area under the curve (AUC) and standard deviation of estimated AUC when using destructive measurement technique : An evaluation of available methods. Ind. J. Pharm. Sci., 62(4) 291- 295, 2000. List of Publications – Cell, Molecular Biology and Biotechnology
Barh D., Agate V., Dhawan D., Agate V., Bajpai V., Padh H. Cancer Biomarkers for Diagnosis, Prognosis and Therapy. Ed. Whitehouse D. and Rapley R. In Cellular and Molecular Therapeutics: Wiley (In Press)
Dhawan D. and Padh H. Omics Approaches in Cancer Biomarker and Targeted Anticancer Drug Discovery. ed. Barh D., In:OMICS: Biomedical Perspectives and Applications: CRC Press (In Press).
Jagadale R., Sakhrani N. and Padh H. Drug delivery and drug targeting using therapeutic nanoparticlesInNanotechnology:Present Status and Future Prospects in Developing Countries. Padh H., Aduda B.O. and de Alwis A. P. Editors.ISBN : 9788170357070, 2011, p. 110-132.
Dipali Dhawan and Harish Padh. Pharmacogenetics: Technologies to detect copy number variations. Current Opinion in Molecular Therapeutics. 11(6) 670 – 680, 2009. [IF 2.913]
Bhavesh Vats, Harish Padh. Efficient cell lysis method for isolation of total RNA from slime mold Dictyostellium: Applicability in preparation of cDNA.
International Journal of Biotechnology and Biochemistry (IJBB). Vol. 5(1) 51 – 62, 2009.
Vats Bhavesh; Padh Harish. DNA passage to nuclei: role of endo-lysosomal circuit in eukaryotic Dictyostelium. Canadian journal of microbiology. Vol. 55(5) 617 - 21, 2009. [IF1.102]
Johanna Sistonen, Silvia Fuselli, Jukka Palo, Neelam Chauhan, Harish Padh, Antti Sajantila. Pharmacogenetic variation at CYP2C9, CYP2C19, and CYP2D6 at global and microgeo- graphic scales. Pharmacogenetics and genomics. 19(2):170-179, 2009. [IF4.409]
Milee Agarwal, Neeta Shrivastava and Harish Padh. Advances in molecular marker techniques and their applications in plant sciences. Plant Cell Reports, 27 (4), 617-631, 2008. [IF 1.946]
Sonia Guha and Harish Padh. Cathepsins: Fundamental effectors Endolysosomal Proteolysis. Indian Journal of Biochemistry & Biophysics, Vol.45, 75-90, 2008. [IF 0.574]
Bhavesh Vats, Harish Padh. Development of soil amoeba Dictyostelium discoideum as an expression system for recombinant human erythropoietin. World J. Microbiol Biotechnol, 23, 1511-1518, 2007. [IF 0.945]
Sonia Guha, M. Rajani, Harish Padh. Identification and characterization of lipids from endosomes purified by electromagnetic chromatography. Indian Journal of Biochemistry & Biophysics, 44, 2007. [IF 0.574]
Astha Varma, Harish Padh, Neeta Shrivastava. Plant genomic DNA isolation: An art or a science. Biotechnol. J. 2, 386 - 392, 2007.
Nivsarkar Manish, Patel M., Padh H., Cherian B. And Shrivastava N. Blastocyst implantation failure in mice due to “non receptive endometrium” endometrial alterations by Hiiscus rosa sinnensis leaf extract. Contraception 71 (3), 227-230, 2005. [IF 2.327]
Anshu Srivastava, Neeta Shrivastava, Niranjan Kanaki, M. Rajani and Harish Padh. Axillary bud multiplication and phytochemical evaluation of Kurchi: An Indian medicinal plant. Proceedings book named Biotechnology for a Better Future of 26th meeting of the Plant Tissue Culture Association of India, held in Mangalore, pp. 106 - 110, 2004.
Avani Kothari, Harish Padh and Neeta Shrivastava. In vitro plantlet regeneration from the axillary bud of Clerodendrum inerme. Proceedings book named Biotechnology for a Better Future of 26th meeting of the Plant Tissue Culture Association of India, held in Mangalore, pp. 138 - 142, 2004.
Chaula Raval, V. C. Shah and Harish Padh. Biotechnology and its implication in healthcare. Perspectives in Cytology and Genetics, 11, 19 - 27, 2004.
Nidhi Neekhra and Harish Padh. An insight into molecular mechanism of endocytosis. Indian Journal of Biochemistry & Biophysics, 41, 69 - 80, 2004.
Neeta Shrivastava and Harish Padh. Monoclonal antibodies (mAb) as therapeutics. Proc. of AP Akademi of Science, 8(1): 43 - 46, 2004.
Deval Shah and Harish Padh. Biotechnology in healthcare: Avenues for developing countries. Pharma Technology Index, Fifth Edition, 294 - 298, 2003.
Nidhi Neekhra and Harish Padh. Molecular Mechanism of Endocytosis. Proc. of Second International Symposium on Molecular Medicines pp. 184 - 204, 2002.
Manish Nivsarkar, Neeta Shrivastava, Manoj Patel, Harish Padh and Cherian Bapu. Sperm membrance modulation by Sapindus mukorossi during sperm maturation. Asian J. Andrology. 4(3):233 - 235, 2002. [IF 2.059]
Bandhana Katoch, Sonia Sebastian, Sudhir Sahdev, Harish Padh, Seyed E. Hasnain and Rasheedunnisa Begum. Programmed cell death and its clinical implications. Indian Journal of Experimental Biology. 40:513 - 524, 2002. . [IF 0.599]
89. Harish Padh. Pharmacokinetics : Chemical vs. Protein therapeutics.
Pharmaceutical News. 8(5), 2001.
Harish Padh. Human genome project and pharmacogenomics: Leading towards individualized medication. Indian Drugs. 38(4) 160 -163, 2001
Meena Rai and Harish Padh. Expression systems for production of heterologous proteins. Current Sci. Vol. 80(9) 1121 - 1128, 2001. [IF 0.74]
Manish Nivsarkar, Aditya Sethi, Cherian Bapu, Manoj Patel and Harish Padh. Involvement of Endometrial Membrane Sulphydryl groups in blastocyst implantation: Sulphydryl groups as a potential target for contraceptive research. Contraception. 64(4), 255-259, 2001. [IF 2.327]
Nivsarkar M., C. Bapu and H. Padh. Alfa-terthienyl a new plant derived insecticide. Current Science. 81(6), 667-672, 2001. [IF 0.74]
Padh, H. Biotechnology in Developing Countries: A Technology Imperative. BioPharm, Vol. 12(7), 18 & 19 (U.S.A.), 1999.
Harish Padh. Human genome project and pharmacogenomics: Leading towards individualized Medication. Published in the Souvenir released on the occasion of the IV International Symposium on Innovations in Pharmaceutical Sciences & Technology, B. V. Patel PERD Centre, Ahmedabad, February, 2000.
Padh, H. (1999) "Biotechnology and Healthcare: Strategy for India and Other Developing Countries", in Proceedings of the International Conference on Changing Pattern of Health in Developing Countries, held at Vadodara, India, from January 21-23, 1998.
Padh, H. Biotechnology in India: The Technology Imperative. Current Science72, 434-436, 1997. [IF 0.74]
Padh, H. Biotechnology in Healthcare: Strategy for India. Pharma Pulse3, No. 18, p12, 1997.
Padh, H. Biotechnology in Healthcare: The way ahead. Pharma Pulse3, No. 19, p7, 1997.
100. Padh, H. Biotechnology: Its Global Impact and Relevance to India. Current Science71, 670-676, 1996. [IF 0.74]
Padh, H. and Tanjore, S. Localization of cyclic-AMP receptors with acidosomes in Dictyostelium discoideum.FEBS Letters, 368: 358-362, 1995. [IF 3.54]
Padh, H. Electromagnetic purification of complexes of endocytic vacuoles and acidosomes from Dictyostelium. Arch. Biochem. Biophys, 316: 643-648, 1995. [IF 2.626]
103. Nolta, K., Padh, H. and Steck, T. L. An immunocytochemical analysis of the
vacuolar proton pump in Dictyosteliumdiscoideum. J. Cell Sci.105: 849-859, 1993. [IF 6.247]
104. Padh, H. Organelle isolation and marker enzyme assay. In Tested studies for
laboratory teaching: Proceeding of the 13th workshop/conference of the
Association for Biology Laboratory Education (ABLE). Corey A. Goldman, editor. pp129-146, 1992.
105. Nolta, K., Padh, H. and Steck, T. L. Acidosomes from Dictyostelium: initial
biochemical characterization. J. Biol. Chem., 266: 18318-18323, 1991. [IF 5.52]
106. Padh, H., Lavasa, M. and Steck, T. L. Reconstitution of the association of
endocytic vacuoles and acidosomes from DictyosteliumJ. Biol. Chem.,266: 12123-12126, 1991. [IF 5.52]
107. Padh, H., Lavasa, M. and Steck, T. L. Endosomes are acidified by association
with discrete proton-pumping vacuoles in DictyosteliumJ. Biol. Chem.,266: 5514- 5520, 1991 [IF 5.52]
108. Padh, H., Lavasa, M. and Steck, T. L. Prelysosomal acidic vacuoles in
Dictyostelium discoideum.J. Cell Biol.,108: 865-874, 1989. [IF 9.12]
109. Padh, H., Lavasa, M. and Steck, T. L. Characterization of a vacuolar proton
ATPase in Dictyostelium discoideum.Biochim. Biophys. Acta,982: 271-278, 1989. [IF 2.9]
Padh, H. and Brenner, M. The role of enzyme sequestration in the regulation of adenylate cyclase of Dictyostelium discoideum.J. Biol. Chem., 260: 3613-3616 1985. [IF 5.52]
Padh, H. and Brenner, M. Studies of the guanylate cyclase of the social ameba Dictyostelium discoideum.Arch. Biochem. Biophys., 229: 73-80, 1984. [IF 2.626]
112. Brenner, M. and Padh, H. Forskolin does not activate cyclic AMP synthesis in
Dictystelium discoideum in vivo or in vitro.J. Cyclic Nucleotide and Protein Phosphorylation Res., 9: 297-303, 1983. List of Publications – General
113. Rajani M., Harish Padh. Need to ensure safety of Bhasmas. Chronicle Pharmabiz 5(37) 8, 2005.
114. Harish Padh, Shubha Rani and Manish Nivsarkar. Pharma Industry –
Opportunities Post 2005. Proceedings of Seminar on Chemicals & Pharmaceuticals., Global Investors’ Summit, 2005.
Harish Padh and Rajani M. Integration of healthcare systems - Getting best of both the worlds. Saket Industrial Digest. 18 - 21, 2001.
116. Harish Padh. Pharmacokinetics: Chemical vs. Protein therapeutics.
Pharmaceutical News. 8(5), 2001.
M. & Harish Padh. Herbal Drugs - A Perspective. Published in the Souvenir
released on the occasion of the IV International Symposium on Innovations in Pharmaceutical Sciences & Technology, B. V. Patel PERD Centre, Ahmedabad, February, 2000.
118. Padh, H. Vitamin C: Newer insights into its biochemical functions. Nutrition Reviews49: 65-70, 1991. [IF 3.503] Review: Cellular functions of ascorbic acid. Biochemistry and Cell Biology, 68: 1166-73, 1990. [IF 2.473]
Padh, H. and Aleo, J. J. Ascorbic acid transport by 3T6 fibroblasts: Regulation by and purification of human serum complement factor. J. Biol. Chem.,264: 6065- 6069, 1989. [IF 5.52]
121. Padh, H. and Aleo, J. J. Characterization of ascorbic acid transport by 3T6
fibroblasts. Biochim. Biophys. Acta, 901: 283-290, 1987. [IF 2.9]
122. Padh, H. and Aleo, J. J. Activation of serum complement generates inhibitor of
ascorbate transport. Ann. N.Y. Acad. Sci., 498: 502-505, 1987. [IF 2.303]
123. Padh, H. and Aleo, J. J. Activation of serum complement leads to inhibition of
ascorbic acid transport. [Proc. Soc.] Exp. Biol. Med., 185:153-157, 1987. [IF 2.64]
124. Subramoniam, A., Padh, H. and Aleo, J. J. Polymyxin B-sulphate induces pH-
dependent increase in calcium influx in cultured fibroblasts. Biochem. Med. & Metabolic Biol., 35: 65-71, 1986 .
Padh, H. and Aleo, J. J. Stability of ascorbic acid in solution. IRCS Med. Sci., 13: 1028-1029, 1985.
Aleo, J. J. and Padh, H. Inhibition of ascorbic acid uptake by endotoxin; evidence of mediation by serum factor(s). Proc. Soc. Exp. Biol. Med., 179: 128-131, 1985.
127. Padh, H., Subramoniam, A. and Aleo, J. J. Glucose inhibits cellular ascorbic acid
uptake by fibroblasts in vitro.Cell Biol. Int. Report., 9: 531-538, 1985. [IF 1.619]
128. Subramoniam, A., Padh, H. and Aleo, J. J. Factors influencing calcium influx in
endotoxin-challenged fibroblasts. Proc. Soc. Exp. Biol. Med., 178: 50-59, 1985.
Aleo, J. J., Padh, H. and Subramoniam, A. Possible role of calcium in periodontal disease. J. Periodontology, 55: 642-647, 1984. [IF1.961]
Aleo, J. J., Padh, H. and Subramoniam, A. Influence of glutamine on calcium uptake by endotoxin challenged fibroblast. IRCS Med. Sci., 12: 996-997, 1984.
131. Padh, H. and Venkitasubramanian, T. A. Lack of adenosine 3',5'-monophosphate
receptor protein and apparent lack of expression of adenosine 3',5'-monophosphate functions in Mycobacterium smegmatis CDC46. Microbios, 27: 68-78, 1980.
132. Padh, H. and Venkitasubramanian, T. A. Comparison of the in vivo and in vitro
activities of adenylate cyclase from Mycobacterium tuberculosis H37Ra (NCTC 7471). Ind. J. Biochem. Biophys., 16: 131-135, 1979. [IF 0.579]
133. Padh, H. and Venkitasubramanian, T.A. Proceedings of the symposium on
Receptors in Biological Systems. Organized at Indian Institute of Experimental Medicine, Calcutta, India, March 21-23, p. 87-96, 1978.
134. Ahmed, N., Tyagi, A.K., Padh, H. and Venkitasubramanian, T. A. Alkaline
phosphatase activity in Mycobacterium smegmatis.Ind. J. Chest Diseases and Allied Sciences, 20: 11-20, 1978.
135. Padh, H. and Venkitasubramanian, T.A. Adenylate cyclase activity of
Mycobacterium smegmatis CDC 46. Ind.J. of Biochem. Biophys., 15: 141-143, 1978. [IF 0.579]
136. Padh, H. and Venkitasubramanian, T.A. Adenosine 3', 5'-monophosphate in
mycobaterium. Life Sciences,20: 1273-1280, 1977. [IF 2.583]
Padh, H. Adenylate cyclase of mycobacteria. Ind. J. Chest Diseases and Allied Sciences., 18: 115-122, 1977.
Padh, H. and Venkitasubramanian, T.A. Cyclic adenosine 3', 5'-monophosphate in mycobacteria. Ind. J. Biochem. Biophys., 13: 413-414, 1976. [IF 0.579]
139. Padh, H. and Venkitasubramanian, T.A. Adenosine 3', 5'-monophosphate in
Mycobacterium phlei and Mycobacterium tuberculosis H37Ra. Microbios, 16: 183- 189, 1976 .
140. Padh, H. and Dhariwal, K.R. Cyclic Nucleotides. Science Reporter, 12: 303-308,
Padh, H. and Venkitasubramanian, T. A. Use of enzymes as medicines. J. Health Sciences: Arogya1: 101-105, 1975. [IF 0.654] Projects (handled and ongoing): Government:
¾ 2012- 2015, Awarded by the Indian Council of Medical Research for Development of
vaccine against multidrug resistant shigella dysenteriae type-1
¾ 2009-, Awarded by the Department of Pharmaceuticals, Government of India,
No.52/137/2008-NIPER for Creation of Incubator Facilities at NIPER - Ahmedabad
¾ 2009- , Awarded by Industries Commissioner, Government of Gujarat,
No.IC/Salt/R&D/09-10/2565 for Centre of Excellence for Quality Assurance of Drugs
¾ 2009- 2011, Awarded by Industries Commissioner, Government of Gujarat ,
No.IC/Salt/R&D/09-10/2574 for Innovative Product Development Platform for SMEs
2009-2011, Awarded by Industries Commissioner, Government of
GujaratNo.IC/Salt/R&D/09-10/2568 for Pharma Biotech Incubator Facility
2009-2011, Awarded byIndustries Commissioner, Government of Gujarat,
No.IC/Salt/R&D/09-10/2562 for Biotech Pharma Link Unit for Converting Biological
¾ 2009-2012, Awarded by Department of Pharmaceuticals, Government of India for
Development of novel drug delivery system for treatment of Tuberculosis.
¾ 2007-2012, Awarded by Department of Biotechnology, India for Drug Delivery and Drug
¾ 2007-2010, Awarded by Department of Biotechnology, India for Genetic variation in drug
response in Indian population: Correlation between Genotype and Phenotype
¾ 2007- , Awarded by Industries Commissioner, Government of Gujarat To establish
Clinical Trials and Data Management for Healthcare Industries
¾ 2006-2009, Awarded by Department of Science & Technology, Government of India for
Synthesis and evaluation of Novel Cephalosporins as antibacterial agents
¾ 2000-2001, Awarded by Industries Commissioner, Government of GujaratTo set up Drug
¾ 2000 (April to September), Awarded by UNIDO, Switzerland , for Pharma cluster in
Ahmedabad - diagnostics for intervention
¾ 2002-2005, Awarded by Department of Biotechnology, India for Phytochemical
evaluation and micropropagation of medicinal plants
¾ 2009-2002, Awarded by Department of Science & Technology, Government of India for
Processing of LDL and cardiovascular diseases
¾ 2009-2002, Awarded by Council of Scientific and Industrial Research, for Gene
¾ 2000-2001, Awarded by Industries Commissioner, Government of Gujarat, For Gujarat
¾ 2000-2001, Awarded by Industries Commissioner, Government of Gujarat, To set up
¾ 1998-2000, Awarded by National Dairy Development Board, for Developing Eukaryotic
¾ 1992-1995, Awarded by National Science Foundation (NSF) No. MCB-9113366, for
Endocytosis in Dictyostelium: Role of Acidosomes as an Early Endocytic Compartment
¾ 1991-1992, Awarded by National Institutes of Health (NIH) grant No. DK42086, for
¾ 1989-1991, Awarded by Cystic Fibrosis Foundation/University of Chicago, for Chloride
channel in acidosomes of Dictyostelium
¾ 1983-1986, Awarded by National Institutes of Health (NIH) grant No. DE 05766, for
Vitamin C deficiency in diabetic gingivitis
¾ 1984 (January to December), Awarded for National Institutes of Health (NIH) grant No.
RR-5339 for Vitamin C transport in fibroblast
Advisor/membership:
¾ Government of Gujarat, on pharmaceuticals and biotechnology matters
¾ Developed proposal and undertook feasibility for Gujarat Biotech Park at Savli
¾ Developed proposal and designing National Centre for Medical Device for NIPER
¾ Developed, designed and run National Institute for Pharmaceutical Education &
Research (NIPER) at Ahmedabad, and developing Campus for the same at
¾ On board of advisors for SICART, GIRDA, ACTON Biotech, Vasu Pharma,
¾ Ex- senate member of North Gujarat University (3 years)
¾ Member of the Board of Gujarat Venture Finance Ltd. (BT), Ahmedabad
¾ Gujarat State Biotech Mission (GSBTM) Member of Executive Committee, Governing
Body as well as Gujarat State Biotech Council
¾ Steering Committee for NIPERs, Dept. of Pharmaceuticals, Govt. of India (2007-10)
¾ Member of several committees (NBA, AICTE, DCGI etc)
¾ Member: AICTE Western Regional Committee
¾ Member: Indian Pharmacopoeia Working Group
¾ Member: Editorial Board, Indian Journal of Pharmaceutical Sciences and Indian Drugs
¾ Life Member: Society of Biological Chemistry, India
¾ Life Member: Indian Society for Cell Biology.
¾ Life Member: Indian Society for Biomedical Engineering.
¾ Life member: Gujarat Science Academy: American Society for Cell Biology
¾ Member: American Society for Biochemistry & Molecular Biology
¾ Member: DBT, GOI appointed expert member on IBS committees of several pharma
……………………………………………………………………………………………………………
CURRENT OPINION 2007 Adis Data Information BV. All rights reserved. The National Institute for Health and Clinical Excellence (NICE) and Drug Treatment for Alzheimer’s Disease Steve Iliffe University College London, London, England Abstract Britain’s National Institute for Health and Clinical Excellence (NICE) hasrecently issued guidance that restricts the use of cholinesteras
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