Microsoft word - prof. harish padh

Dr. Harish Padh
Department of Cell and Molecular Biology, B.V. Patel Pharmaceutical Education and Research Development (PERD) Centre, Sarkhej Gandhinagar Highway, Thaltej, Ahmedabad-380054 Email: hpadh@yahoo.com
Current position:
Vice Chancellor, Sardar Patel University, Vallabh Vidyanagar, Gujarat
and Advisor in B.V.Patel PERD centre andNIPER - Ahmedabad
…………………………………………………………………………………………………… Previous positions:
Project Director: NIPER-Ahmedabad (2007-2010)
Director: B.V. Patel PERD centre, Ahmedabad (1999-2010)
Visiting Faculty: University of North Carolina, Chapel Hill, North Carolina, USA (2006 May-Oct) Professor: M.S. University of Baroda, Vadodara, INDIA (1996-2001) Assistant Director and Associate Professor: Northwestern University, Center for Biotechnology, Evanston, IL. USA (1993-95) Assistant Professor-Research: University of Chicago, Department of Biochemistry & Molecular Biology (Jan 1987-sep 1992) Associate Professor-Research: University of Chicago, Department of Biochemistry & Molecular Biology (Oct 1992-Apr 1993) Research Associate: Temple University Health Sciences Center, Philadelphia (Jan 1981-Dec 1983) Research Assistant Professor: Temple University Health Sciences Center, Philadelphia (Jan1984-Dec 1986) Leon Journey Fellow: St. Jude Children’s Research Hospital, Memphis, TN (1979-1980) Lecturer: S. P. University, Department of Biosciences, Vallabh Vidyanagar, India .…………………………………………………………………………………. Education:
¾ Ph.D. (Biochemistry): University of Delhi in 1978.
¾ M. Sc. (Biochemistry)–M. S. University Baroda, 1973.
…………………………………………………………………………………………………………… Research areas:
Cell and Molecular Biology, Biotechnology, Pharmacogenetics, Drug Delivery
………………………………………………………………………………………………………… Publications:
Number of research papers and reviews published: Over 130+
Number of additional abstracts and presentations: over 200+
Total citation: 1883: H-index: 22; i10 Index: 46
List of Publications
Padh H., Aduda B.O. and de Alwis A. P. Editors. Nanotechnology : Present Status
and Future Prospects in Developing Countries
. ISBN : 9788170357070. 2011, NAM
S&T Center, New Delhi. Daya Publishing House.
Research Publications
In three sections
: (Impact Factors for few publications listed as IF)
Pharmaceuticals Sciences
Cell, Molecular Biology and Biotechnology Related
General
List of Publications – Related to Pharmaceutical Sciences
D. N. Azmanov, S Dimitrova, L. Florez, S. Cherninkova, D. Draganov, B. Morar,
R. Saat, M. Juan, J. I Arostegui, S. Ganguly, H. Soodyall, S. Chakrabarti, Harish
Padh
, M. A Lo´pez-Nevot, V. Chernodrinska, B. Anguelov, P. Majumder, L.
Angelova, R. Kaneva, D. A. Mackey, I. Tournev and L. Kalaydjieva. LTBP2 and
CYP1B1 mutations and associated ocular phenotypes in the Roma/Gypsy
founder population. European Journal of Human Genetics19, 326–333, 2011
[IF 3.6]

Shep, D., Ojha, A., Patel, S., Nivsarkar, M, Jaiswal, V and Padh H. Comparative
bioavailability study of a new formulation of injection of 75 mg. Diclofenac
Sodium in 1 ml. with the conventional injection of 75 mg. Diclofenac Sodium
given in 3 ml. volume. Current Clinical Pharmacology, 6(1), 26 – 29, 2011. [IF
2.8]

Desai, P., Shrivastava, N., and Harish Padh. Production of heterologous proteins
in plants: Strategies for optimal expression. Biotechnology Advances 28, 427-
435, 2010. [IF 8.25]
Shep, D., Ojha, A., Patel, S., Nivsarkar, M, Jaiswal, V and Padh H.
Pharmacokinetic profile of a new formulation of injection diclofenace in Indian
volunteers with BMI> 25. J. Pain Research, 3, 235 – 240, 2010.
Shep, D., Ojha, A., Patel, S., Nivsarkar, M, Jaiswal, V and Padh H.
Bioequivalence and Pharmacokinetic evaluation of two formulations of
paracetamol ER 650 mg: A single dose randomized two period crossover
comparison in healthy Indian adult volunteers. International Journal of Current
Pharmaceutical Research
, 2(4), 28 – 31, 2010.
SG, Banerjee A, Chauhan BF, Padh H, Nivsarkar M, Mehta AA. Inhibitory effect of n-butanol fraction of Moringa oleifera Lam. seeds on
ovalbumin-induced airway inflammation in a guinea pig model of asthma.Int. J.
Toxicol. 28(6):519-27 2009.[IF 1.267]
Hitesh Vaidya, Mandapati Rajani, Vasudevan Sudarsanam, Harish Padh,
Ramesh Goyal. Swertiamarin: A lead from Enicostemma littorale Blume for anti-
hyperlipidaemic effect. European Journal of Pharmacology, 617, 108 – 112,
2009. [IF 2.787]
Ashwini Ojha, Rajeshwari Rathod and Harish Padh. Simultaneous HPLC-UV
determination of rhein and aceclofenac in human plasma. Journal of
Chromatography B, 877, 1145 – 1148, 2009. [IF 2.5]
Ashwini Ojha, Dhaneshwar Shep, Manish Nivsarkar, sweta Patel, Vijayajaiswal and
Harish Padh. Pharmacokinetic profile of a new formulation of injection diclofenac
designed for intradeltoid use. Expert Opinion on Pharmacotherapy, Vol.10 (4) 517 –
522, 2009. [IF 2.077]
Aryamitra Banerjee, arish Padh and Manish Nivsarkar. Role of the calcium
channel in blastocyst implantation: A novel contraceptive target. Journal of
Basic & Clinical Physiology & Pharmacology
, Vol. 20 (1) 43 – 53, 2009. [IF
0.54]

Manish Nivsarkar, Aryamitra Banerjee, Harish Padh. Cyclooxygenase inhibitors: a
novel direction for Alzheimer’s management. Pharmacological Report, 60, 692 –
698, 2008. [IF 2.167]
Rajeshwari Rathod, L. Poorna Chandra Prasad, Shubha Rani, Manish Nivsarkar,
Harish Padh. Estimation of Carvedilol in human plasma by using HPLC-
fluorescence detector and its application to pharmacokinetic study. Journal of
Chromatography B
, 857, 219-223, 2007. [IF 2.5]
Chaula Patel, Minal Patel, Shubha Rani, Manish Nivsarkar, Harish Padh. A new
high performance liquid chromatographic method for quantification of
atomoxetine in human plasma and its application for pharmacokinetic study.
Journal of Chromatography B, 850, 356 - 360, 2007. [IF 2.5]
Prashanth Kumar, Neelam S. Chauhan, Harish Padh, M. Rajani. Search for
antibacterial and antifungal agents from selected Indian medicinal plants.
Journal of Ethnopharmacology, 107, 182 - 188, 2006. [IF 2.26]
Ajay. D Pillai,Shubha Rani, Parendu. D Rathod, Franklin. P Xavier, Harish Padh,
Vasudevan Sudarsanam and Kamala. K Vasu. Tetra substituted thiophenes as
anti-inflammatory agents: Exploitation of analogue-based drug design.
Bioorganic & Medicinal Chemistry, 13, 6685-6692, 2005. [IF 3.075]
Bhupendrasinh Chauhan, Shubha Rani, Swati Guttikar, Anjali Zope, Nimisha
Jadon, Harish Padh. Analytical method development and validation of mianserin
hydrochloride and its metabolite in human plasma by LC-MS. Journal of
Chromatography B
, 823, 69-74, 2005. [IF 2.5]
Ajay. D Pillai,Shubha Rani, Parendu. D Rathod, Franklin. P Xavier, Kamala. K
Vasu,Harish Padh and Vasudevan Sudarsanam.Q.S.A.R Studies on Some
Thiophene Analogs as Anti-inflammatory Agents: Enhancement of Activity by
Electronic Parameters and its Utilization for Chemical Lead Optimization.
Bioorganic & Medicinal Chemistry, 13, 1275-1283, 2005. [IF 3.075]
Milind Bagul, H. Srinivasa, Harish Padh and M. Rajani. A rapid densitometric
method for simultaneous quantification of gallic acid and ellagic acid in herbal raw
materials using HPTLC. J. Sep. Sci., 28, 581-584, 2005. [IF 2.746]
Patel M., Cherian B., Padh H., and Nivsarkar Manish. Olanzepine induced
thrombocythemia in Spargue-Daley rats. Drug Chemical and Toxicology 27(4),
379 - 387, 2004. [IF 1.409]
Shubha Rani, Swati Guttikar, Rajeshwari Rathod, Bapu Cherian, Manish Nivsarkar
and Harish Padh. Determination of oral Meloxicam pharmacokinetic parameters in
Asian Indians: Comparison with a German population. Saudi Pharmaceutical
Journal
, 12 (4), 144 - 149, 2004.
B. Pathak, K. Niranjan, H. Padh, M. Rajani. TLC densitometric method for the
quantification of Eugenol and Gallic acid in Clove. Chromatographia, 60, 241 -
244, 2004. [IF 1.312]
Srinivasa, Milind S. Bagul, Harish Padh, Rajani M. A rapid densitometric method
for the quantification of luteolin in medicinal plants using HPTLC.
Chromatographia, 60, 131-134, 2004. [IF 1.312]
Ajay D. Pillai, Parendu D. Rathod, P.X Franklin., Harish Padh, Kamala K. Vasu, and
V. Sudarsanam. Design, synthesis, and SAR studies of some 5-aliphatic oximino
esters of thiophene as potential anti-inflammatory leads: Comparative biological
activity profile of aliphatic oximes vs aromatic oximes. Biochemical and
Biophysical Research Communications
, 317, 1067-1074, 2004. [IF 2.648]
Ajay D. Pillai, P. D. Rathod, P. X. Franklin, M. Patel, M. Nivsarkar, K. K. Vasu,
Harish Padh, and V. Sudersanam. Novel drug designing approach for dual
inhibitors as anti-inflammatory agents: implication of pyridine template. Biochem
Biophys Res Commun
. 301(1):183-186, 2003.
[IF 2.648]
Rajani M., Saxena N., Ravishankara MN., and Padh H. Evaluation of antimicrobial
activity of Ammoniacum gum from Dorema ammoniacum D. Don. Pharmaceutical
Biology
. 40(7):534-541, 2002. [IF 0.488]
Ravishankara M.N., Neeta Shrivastava, Harish Padh and Rajani M. Evaluation of
antioxidant properties of root bark of Hemidesmus indicus. Phytomedicine.
9(2),:153 - 161, 2002. [IF 2.330]
Ravishankara M.N., Neeta Shrivastava, Harish Padh and Rajani M. Evaluation of
antioxidant properties of root bark of Hemidesmus indicus. Phytomedicine.
9(2),:153 - 161, 2002. [IF2.330]
Ravishankara M.N., Neeta Shrivastava, Harish Padh and Rajani M. HPTLC
method for the estimation of alkaloids from Cinchona officinalis stem bark and its
formulations. Planta Medica 67(3), 294-296, 2001. [IF 1.960]
Ravishankara M.N., Neeta Shrivastava, Padh H. and Rajani M. Sensitive high
performance thin layer chromatography method for the estimation of diospyrin,
antitumor inhibitory agent from stem bark of Diospyrus montana Roxb. Journal of
Chromatography
B. 744:257 - 262, 2000. [IF 2.5]
Padh, H. and Venkitasubramanian, T. A. Use of enzymes as medicines. J.
Health Sciences: Arogya
1: 101-105, 1975. [IF 0.654]
P. X. Franklin, S.Yerande, H. M. Thakar, G. S. Inamdar, R. S. Giri, H. Padh, V. Sudarsanam and Kamala K. Vasu. Synthesis, antiinflammatory and HIV-1 integrase inhibitory activities of 1, 2-Bis[5-thiazolyl] ethane-1, 2-dione derivatives. Indian J. Pharm. Sci., 71 (3), 259 – 263, 2009. AsthaVarma, Harish Padh and Neeta Shrivastava. Andrographolide: A New Plant-Derived Antineoplastic Entity on Horizon. eCAM 2009, doi:10.1093/ecam/nep135. Aryamitra Banerjee, Harish Padh and Manish Nivsarkar. Role of the calcium
channel in blastocyst implantation: A novel contraceptive target. Journal of
Basic & Clinical Physiology & Pharmacology
, Vol. 20 (1) 43 – 53, 2009.
Shubha Rani, Gurmeet Singh, Aryamitra Banerjee, Manish Nivsarkar and Harish
Padh. Single and Multiple dose toxicokinetics of Rofecoxib in Sprague Dawley Rats
: Implication of drug accumulation and sex differences. Adv. Pharmacol Toxicol. 9
(1), 1 – 7, 2008.
Shubha Rani, Aryamitra Banerjee, Manish Nivsarkar, Gurmeet Singh, Minal Patel
and Harish Padh. Serial and sparse sampling approaches in single and multiple
dose toxicokinetic studies: A comparison. Int. J. Pharmacol. Biol. Sci. 2 (1) 71 –
78, 2008.
Ojha Ashwini, Guttikar Swati, Vayeda Chintan, Padh Harish. Determination of
Pitavastatin from human plasma using High Performance Liquid Chromatography
with Flourescence Detection. Chinese Journal of Chromatography, 25 (5),
715-718, 2007.
Ashwini Ojha, Rajeshwari Rathod, Chaula Patel, Harish Padh. LC-MS
Determination of Gabapentin from Human Plasma. Journal of
Chromatographia
, 2007. [IF 1.1]
Neelam Chauhan, Shubha Rani, H. Padh. Pharmacogenetics: Genetic Basis for
Rational Drug Therapy. Indian Journal of Pharmaceutical Sciences, 69(2), 180
-189, 2007. [IF 0.72]
Anti-hyperlipidemic effect of Carica Papaya in sprague dawley rats. Aryamitra
Banerjjee, Rakesh Vaghasiya, Neeta Shri vastava, Harish Padh and Manish
Nivsarkar. Nig. J. Nat. Prod. And Med. 10, 69 - 72, 2006.
Shubha Rani and Harish Padh. Inter-Individual Variation in Pharmacokinetics of
Proton Pump Inhibitors in Healthy Indian Males. Indian Journal of
Pharmaceutical Sciences
, 68(6), 754 - 759, 2006.
Shubha Rani, Monica Verma, Shivaprakash and Harish Padh. Formulations
dependent variability in the pharmacokinetics: A case study with Metformin. W. J.
Med. Sci
., 1(1), 9 - 13, 2006.
Shubha Rani, Swati Guttikar, Anjali Zope, Rajeshwari Rathod, Manish Nivsarkar
and Harish Padh. Zafirlukast pharmacokinetics in healthy Indian male subjects:
Possibility of interethnic variability. Indian J. Allergy Asthma Immunol. 19(2),
69 -73, 2006.
Chauhan B., Rani S., Nivsarkar M. and Padh H. A new liquid-liquid extraction
method for determination of Montelukast in small volume human plasma samples
using HPLC with Fluorescence Detector. Ind. J. Pharma. Sci., 68(4), 517 - 520,
2006.
Manish Nivsarkar, Aryamitra Banerjee, Deval Shah, Jaimic Trivedi, Manoj Patel,
Bapu Cherian and Harish Padh. Reduction in aluminum induced oxidative stress
by Meloxicam in rat brain. Iranian Biomedical Journal, 10(3), 151-155, 2006.
Shubha Rani, M. Nivsarkar, Rajeshwari Rathod, Swati Guttikar and H. Padh.
Bioequivalence of Fenofibrate tablet formulations in healthy Indian male subjects.
Indian J. Pharm. Sci., 67(3) 297 - 301, 2005.
A. Banerjee, N. Shrivastava, A. Kothari, H. Padh and M. Nivsarkar. Antiulcer
activity of methanol extract of Eclipta alba. Indian J. of Pharm. Sci., 67(2) 165 -
168, 2005.
Nivsarkar Manish, Patel M., Padh H., Cherian B. And Shrivastava N. Blastocyst
implantation failure in mice due to “non receptive endometrium” endometrial
alterations by Hibiscus rosa sinnensis leaf extract. Contraception 71 (3), 227-
230, 2005. [IF 2.37]
Cherian B., Rathod R., Guttikar S., Nivsarkar M., Shubha Rani and Padh H. A rapid,
selective and sensitive method for extraction and analysis of Celecoxib in human
plasma. Indian Drugs, 41(4): 221 - 225, 2004.
Shubha Rani and Harish Padh. Evaluation of truncated area under the curve and
truncated area under the curve with limited blood samples in bioequivalence
studies. Indian J. Pharm. Sci., 65(4): 371 - 377, 2003.
Prashanthkumar V., Ravishankara M.N., Bagul M., Padh H., Rajani M. High
performance thin layer chromatographic method for the estimation of rutin from
medicinal plants. Journal of Planar Chromatography - Modern TLC, 16, 386-389,
2003. [IF 1.15]
Padh H. Pharmacokinetics:Chemical v/s protein therapeutics. Indian Drugs.
40(8):437 - 449, 2003.
Milind S. Bagul, Ravishankara M.N., Harish Padh and Rajani M. Phytochemical
evaluation and free radical scavenging properties of rhizome of Bergenia ciliata
(Haw) sternb. Forma ligulata Yeo. J. Natural Remedies. 3: 83-87, 2003.
Ravishankara M.N., Neeta Shrivastava, Harish Padh and Rajani M. Antioxidant
activity of Cinchona officinalis stem bark extracts. Oriental Pharmacy and
Experimental Medicine
, 3(4), 205-211, 2003.
Nivsarkar M., Rathod P., Vasu K., Zope A., Sudarsanam V., Bapu C. And Padh H.
Altered glucose tolerence by a Guanidinothiorea compound in Sprague Dawley
Rats: Possible mechanism(s) for Hyperglycemia. Indian Drugs, 41(5): 294 - 297,
2004.
55. Niranjan K, Ravishankara M.N., Harish Padh and Rajani M. A new spectrophotometric method for the estimation of total alkaloids in the stem bark and
seed of Holarrhena antidysenterica (Linn.) Wall and in the Ayurvedic formulation
Kutajarishta. Journal of Natural Remedies. 2(2): 2002.
Shubha Rani, Guttikar Swati, Zope Anjali, Cherian Bapu, Nivsarkar Manish and
Padh Harish. Pharmacokinetics of olanzapine in Asian Indians and comparison with
other populations: Possibility of population diversity. Indian Drugs. 39(11):583 -588,
2002.
Ravishankara M.N., Neeta Shrivastava., Harish Padh and Rajani M. A simple
spectrophotometric method for the estimation of total alkaloids from seed of Lupinus
albus
L. Indian Drugs. 39(9):494 - 496, 2002.
Nivsarkar M., Mukherjee M., Patel M., Padh H and Bapu C. Launaea nudicaulis
leaf juice exhibits antiinflammatory action on acute and chronic inflammation
models in rats. Indian Drugs. 39(5):290 - 292, 2002.
Rajani M, Ravishankara M.N., Neeta Shrivastava and Harish Padh. HPTLC aided
phytochemical fingerprinting analysis as a tool for evaluation of herbal drugs. A case
study of Ushaq (Ammoniacum gum). J. Planar Chromatogr. 14(1), 34-41, 2001.
[IF 1.15]
Nivsarkar M., P. De, K.B. Patel, A. Katewa, H. Padh and C. Bapu. Subacute
toxicity of COX-2 anti-inflammatory agent in mice. Advances in Pharmacology
and Toxicology
. 2(2) 29-34, 2001.
Manish Nivsarkar and Harish Padh. Pulse of Indian Pharmaceutical Sector -
Issues and opportunities. Indian Pharma Industry: Issues and Options, Saket
Publications
. pp 37-53, 2001
Ravishankara M.N., Neeta Shrivastava, Harish Padh and Rajani M. Simultaneous
determination of four alkaloids of Cinchona officinalis from the stem bark and
formulations containing Cinchona by HPLC methods. Indian Drugs 38(5):248 -
253, 2001.
Ravishankara M.N., Neeta Shrivastava, Mahendru N., Harish Padh and Rajani M.
Simple colourimetric method for the estimation of alkaloids from Cinchona officinalis
stem bark and its formulations. Indian J. Pharm. Sci. 63(1):76 - 78, 2001.
Bapu, P. De, K.B. Patel, A. Katewa, M. Nivsarkar and H. Padh. Sub-acute
toxicity of COX-2 anti-inflammatory agent in rat. Ind. J. Toxicol. 8(2) 163-168,
2001.
Shubha Rani and Harish Padh. Sparse sampling approach in rodent preclinical
pharmacokinetic studies to reduce the use of animals. Ind. J. Pharmacol., 33(3),
192, 2001.
Shubha Rani and Harish Padh. Estimation of area under the curve (AUC) and
standard deviation of estimated AUC when using destructive measurement
technique : An evaluation of available methods. Ind. J. Pharm. Sci., 62(4) 291-
295, 2000.
List of Publications – Cell, Molecular Biology and Biotechnology
Barh D., Agate V., Dhawan D., Agate V., Bajpai V., Padh H. Cancer Biomarkers for Diagnosis, Prognosis and Therapy. Ed. Whitehouse D. and Rapley R. In Cellular and Molecular Therapeutics: Wiley (In Press) Dhawan D. and Padh H. Omics Approaches in Cancer Biomarker and Targeted Anticancer Drug Discovery. ed. Barh D., In:OMICS: Biomedical Perspectives and Applications: CRC Press (In Press). Jagadale R., Sakhrani N. and Padh H. Drug delivery and drug targeting using
therapeutic nanoparticlesInNanotechnology:Present Status and Future Prospects
in Developing Countries. Padh H., Aduda B.O. and de Alwis A. P. Editors.ISBN :
9788170357070, 2011,
p. 110-132.
Dipali Dhawan and Harish Padh. Pharmacogenetics: Technologies to detect
copy number variations. Current Opinion in Molecular Therapeutics. 11(6) 670
– 680, 2009. [IF 2.913]
Bhavesh Vats, Harish Padh. Efficient cell lysis method for isolation of total RNA from slime mold Dictyostellium: Applicability in preparation of cDNA. International Journal of Biotechnology and Biochemistry (IJBB). Vol. 5(1) 51
– 62, 2009.
Vats Bhavesh; Padh Harish. DNA passage to nuclei: role of endo-lysosomal
circuit in eukaryotic Dictyostelium.
Canadian journal of microbiology. Vol.
55(5) 617 - 21, 2009. [IF1.102]
Johanna Sistonen, Silvia Fuselli, Jukka Palo, Neelam Chauhan, Harish Padh,
Antti Sajantila. Pharmacogenetic variation at CYP2C9, CYP2C19, and CYP2D6
at global and microgeo- graphic scales. Pharmacogenetics and genomics.
19(2):170-179, 2009. [IF4.409]
Milee Agarwal, Neeta Shrivastava and Harish Padh. Advances in molecular
marker techniques and their applications in plant sciences. Plant Cell Reports,
27 (4), 617-631, 2008. [IF 1.946]
Sonia Guha and Harish Padh. Cathepsins: Fundamental effectors Endolysosomal
Proteolysis. Indian Journal of Biochemistry & Biophysics, Vol.45, 75-90, 2008.
[IF 0.574]
Bhavesh Vats, Harish Padh. Development of soil amoeba Dictyostelium
discoideum
as an expression system for recombinant human erythropoietin.
World J. Microbiol Biotechnol, 23, 1511-1518, 2007. [IF 0.945]
Sonia Guha, M. Rajani, Harish Padh. Identification and characterization of lipids from
endosomes purified by electromagnetic chromatography. Indian Journal of
Biochemistry & Biophysics
, 44, 2007. [IF 0.574]
Astha Varma, Harish Padh, Neeta Shrivastava. Plant genomic DNA isolation: An
art or a science. Biotechnol. J. 2, 386 - 392, 2007.
Nivsarkar Manish, Patel M., Padh H., Cherian B. And Shrivastava N. Blastocyst
implantation failure in mice due to “non receptive endometrium” endometrial
alterations by Hiiscus rosa sinnensis leaf extract. Contraception 71 (3), 227-230,
2005. [IF 2.327]
Anshu Srivastava, Neeta Shrivastava, Niranjan Kanaki, M. Rajani and Harish
Padh. Axillary bud multiplication and phytochemical evaluation of Kurchi: An
Indian medicinal plant. Proceedings book named Biotechnology for a Better
Future
of 26th meeting of the Plant Tissue Culture Association of India, held in
Mangalore, pp. 106 - 110, 2004.
Avani Kothari, Harish Padh and Neeta Shrivastava. In vitro plantlet regeneration
from the axillary bud of Clerodendrum inerme. Proceedings book named
Biotechnology for a Better Future of 26th meeting of the Plant Tissue Culture
Association of India, held in Mangalore, pp. 138 - 142, 2004.
Chaula Raval, V. C. Shah and Harish Padh. Biotechnology and its implication in
healthcare. Perspectives in Cytology and Genetics, 11, 19 - 27, 2004.
Nidhi Neekhra and Harish Padh. An insight into molecular mechanism of
endocytosis. Indian Journal of Biochemistry & Biophysics, 41, 69 - 80, 2004.
Neeta Shrivastava and Harish Padh. Monoclonal antibodies (mAb) as therapeutics.
Proc. of AP Akademi of Science, 8(1): 43 - 46, 2004.
Deval Shah and Harish Padh. Biotechnology in healthcare: Avenues for developing
countries. Pharma Technology Index, Fifth Edition, 294 - 298, 2003.
Nidhi Neekhra and Harish Padh. Molecular Mechanism of Endocytosis. Proc. of
Second International Symposium on Molecular Medicines
pp. 184 - 204, 2002.
Manish Nivsarkar, Neeta Shrivastava, Manoj Patel, Harish Padh and Cherian Bapu.
Sperm membrance modulation by Sapindus mukorossi during sperm maturation.
Asian J. Andrology. 4(3):233 - 235, 2002. [IF 2.059]
Bandhana Katoch, Sonia Sebastian, Sudhir Sahdev, Harish Padh, Seyed E.
Hasnain and Rasheedunnisa Begum. Programmed cell death and its clinical
implications. Indian Journal of Experimental Biology. 40:513 - 524, 2002. . [IF
0.599]

89. Harish Padh. Pharmacokinetics : Chemical vs. Protein therapeutics. Pharmaceutical News. 8(5), 2001.
Harish Padh. Human genome project and pharmacogenomics: Leading towards
individualized medication. Indian Drugs. 38(4) 160 -163, 2001
Meena Rai and Harish Padh. Expression systems for production of heterologous
proteins. Current Sci. Vol. 80(9) 1121 - 1128, 2001. [IF 0.74]
Manish Nivsarkar, Aditya Sethi, Cherian Bapu, Manoj Patel and Harish Padh.
Involvement of Endometrial Membrane Sulphydryl groups in blastocyst
implantation: Sulphydryl groups as a potential target for contraceptive research.
Contraception. 64(4), 255-259, 2001. [IF 2.327]
Nivsarkar M., C. Bapu and H. Padh. Alfa-terthienyl a new plant derived
insecticide. Current Science. 81(6), 667-672, 2001. [IF 0.74]
Padh, H. Biotechnology in Developing Countries: A Technology Imperative.
BioPharm, Vol. 12(7), 18 & 19 (U.S.A.), 1999.
Harish Padh. Human genome project and pharmacogenomics: Leading towards
individualized Medication. Published in the Souvenir released on the occasion of
the IV International Symposium on Innovations in Pharmaceutical Sciences &
Technology, B. V. Patel PERD Centre, Ahmedabad, February, 2000.
Padh, H. (1999) "Biotechnology and Healthcare: Strategy for India and Other
Developing Countries
", in Proceedings of the International Conference on
Changing Pattern of Health in Developing Countries, held at Vadodara, India,
from January 21-23, 1998.
Padh, H. Biotechnology in India: The Technology Imperative. Current
Science72
, 434-436, 1997. [IF 0.74]
Padh, H. Biotechnology in Healthcare: Strategy for India. Pharma Pulse3, No.
18, p12, 1997.
Padh, H. Biotechnology in Healthcare: The way ahead. Pharma Pulse3, No. 19,
p7, 1997.
100. Padh, H. Biotechnology: Its Global Impact and Relevance to India. Current
Science71, 670-676, 1996. [IF 0.74]
Padh, H. and Tanjore, S. Localization of cyclic-AMP receptors with acidosomes
in Dictyostelium discoideum.FEBS Letters, 368: 358-362, 1995. [IF 3.54]
Padh, H. Electromagnetic purification of complexes of endocytic vacuoles and
acidosomes from Dictyostelium. Arch. Biochem. Biophys, 316: 643-648, 1995.
[IF 2.626]

103. Nolta, K., Padh, H. and Steck, T. L. An immunocytochemical analysis of the vacuolar proton pump in Dictyosteliumdiscoideum. J. Cell Sci.105: 849-859,
1993. [IF 6.247]
104. Padh, H. Organelle isolation and marker enzyme assay. In Tested studies for laboratory teaching: Proceeding of the 13th workshop/conference of the Association for Biology Laboratory Education (ABLE). Corey A. Goldman, editor. pp129-146, 1992. 105. Nolta, K., Padh, H. and Steck, T. L. Acidosomes from Dictyostelium: initial biochemical characterization. J. Biol. Chem., 266: 18318-18323, 1991. [IF 5.52]
106. Padh, H., Lavasa, M. and Steck, T. L. Reconstitution of the association of endocytic vacuoles and acidosomes from DictyosteliumJ. Biol. Chem.,266:
12123-12126, 1991. [IF 5.52]
107. Padh, H., Lavasa, M. and Steck, T. L. Endosomes are acidified by association with discrete proton-pumping vacuoles in DictyosteliumJ. Biol. Chem.,266: 5514-
5520, 1991 [IF 5.52]
108. Padh, H., Lavasa, M. and Steck, T. L. Prelysosomal acidic vacuoles in Dictyostelium discoideum.J. Cell Biol.,108: 865-874, 1989. [IF 9.12]
109. Padh, H., Lavasa, M. and Steck, T. L. Characterization of a vacuolar proton ATPase in Dictyostelium discoideum.Biochim. Biophys. Acta,982: 271-278,
1989. [IF 2.9]
Padh, H. and Brenner, M. The role of enzyme sequestration in the regulation of
adenylate cyclase of Dictyostelium discoideum.J. Biol. Chem., 260: 3613-3616
1985. [IF 5.52]
Padh, H. and Brenner, M. Studies of the guanylate cyclase of the social ameba
Dictyostelium discoideum.Arch. Biochem. Biophys., 229: 73-80, 1984. [IF
2.626]

112. Brenner, M. and Padh, H. Forskolin does not activate cyclic AMP synthesis in Dictystelium discoideum in vivo or in vitro.J. Cyclic Nucleotide and Protein
Phosphorylation Res.
, 9: 297-303, 1983.
List of Publications – General
113. Rajani M., Harish Padh. Need to ensure safety of Bhasmas. Chronicle
Pharmabiz 5(37) 8, 2005.
114. Harish Padh, Shubha Rani and Manish Nivsarkar. Pharma Industry – Opportunities Post 2005. Proceedings of Seminar on Chemicals &
Pharmaceuticals., Global Investors’ Summit, 2005.
Harish Padh and Rajani M. Integration of healthcare systems - Getting best of both
the worlds. Saket Industrial Digest. 18 - 21, 2001.
116. Harish Padh. Pharmacokinetics: Chemical vs. Protein therapeutics. Pharmaceutical News. 8(5), 2001.
M. & Harish Padh. Herbal Drugs - A Perspective. Published in the Souvenir
released on the occasion of the IV International Symposium on Innovations in
Pharmaceutical Sciences & Technology, B. V. Patel PERD Centre, Ahmedabad,
February, 2000.
118. Padh, H. Vitamin C: Newer insights into its biochemical functions. Nutrition
Reviews49: 65-70, 1991. [IF 3.503]
Review: Cellular functions of ascorbic acid. Biochemistry and Cell
Biology, 68: 1166-73, 1990. [IF 2.473]
Padh, H. and Aleo, J. J. Ascorbic acid transport by 3T6 fibroblasts: Regulation by
and purification of human serum complement factor. J. Biol. Chem.,264: 6065-
6069, 1989. [IF 5.52]
121. Padh, H. and Aleo, J. J. Characterization of ascorbic acid transport by 3T6 fibroblasts. Biochim. Biophys. Acta, 901: 283-290, 1987. [IF 2.9]
122. Padh, H. and Aleo, J. J. Activation of serum complement generates inhibitor of ascorbate transport. Ann. N.Y. Acad. Sci., 498: 502-505, 1987. [IF 2.303]
123. Padh, H. and Aleo, J. J. Activation of serum complement leads to inhibition of ascorbic acid transport. [Proc. Soc.] Exp. Biol. Med., 185:153-157, 1987. [IF 2.64]
124. Subramoniam, A., Padh, H. and Aleo, J. J. Polymyxin B-sulphate induces pH- dependent increase in calcium influx in cultured fibroblasts. Biochem. Med. &
Metabolic Biol.
, 35: 65-71, 1986 .
Padh, H. and Aleo, J. J. Stability of ascorbic acid in solution. IRCS Med. Sci., 13:
1028-1029, 1985.
Aleo, J. J. and Padh, H. Inhibition of ascorbic acid uptake by endotoxin; evidence of
mediation by serum factor(s). Proc. Soc. Exp. Biol. Med., 179: 128-131, 1985.
127. Padh, H., Subramoniam, A. and Aleo, J. J. Glucose inhibits cellular ascorbic acid uptake by fibroblasts in vitro.Cell Biol. Int. Report., 9: 531-538, 1985. [IF 1.619]
128. Subramoniam, A., Padh, H. and Aleo, J. J. Factors influencing calcium influx in endotoxin-challenged fibroblasts. Proc. Soc. Exp. Biol. Med., 178: 50-59, 1985.
Aleo, J. J., Padh, H. and Subramoniam, A. Possible role of calcium in periodontal
disease. J. Periodontology, 55: 642-647, 1984. [IF1.961]
Aleo, J. J., Padh, H. and Subramoniam, A. Influence of glutamine on calcium uptake
by endotoxin challenged fibroblast. IRCS Med. Sci., 12: 996-997, 1984.
131. Padh, H. and Venkitasubramanian, T. A. Lack of adenosine 3',5'-monophosphate receptor protein and apparent lack of expression of adenosine 3',5'-monophosphate
functions in Mycobacterium smegmatis CDC46. Microbios, 27: 68-78, 1980.
132. Padh, H. and Venkitasubramanian, T. A. Comparison of the in vivo and in vitro activities of adenylate cyclase from Mycobacterium tuberculosis H37Ra (NCTC
7471). Ind. J. Biochem. Biophys., 16: 131-135, 1979. [IF 0.579]
133. Padh, H. and Venkitasubramanian, T.A. Proceedings of the symposium on Receptors in Biological Systems. Organized at Indian Institute of Experimental
Medicine,
Calcutta, India, March 21-23, p. 87-96, 1978.
134. Ahmed, N., Tyagi, A.K., Padh, H. and Venkitasubramanian, T. A. Alkaline phosphatase activity in Mycobacterium smegmatis.Ind. J. Chest Diseases and
Allied Sciences
, 20: 11-20, 1978.
135. Padh, H. and Venkitasubramanian, T.A. Adenylate cyclase activity of Mycobacterium smegmatis CDC 46. Ind.J. of Biochem. Biophys., 15: 141-143,
1978. [IF 0.579]
136. Padh, H. and Venkitasubramanian, T.A. Adenosine 3', 5'-monophosphate in mycobaterium. Life Sciences,20: 1273-1280, 1977. [IF 2.583]
Padh, H. Adenylate cyclase of mycobacteria. Ind. J. Chest Diseases and Allied
Sciences.
, 18: 115-122, 1977.
Padh, H. and Venkitasubramanian, T.A. Cyclic adenosine 3', 5'-monophosphate in
mycobacteria. Ind. J. Biochem. Biophys., 13: 413-414, 1976. [IF 0.579]
139. Padh, H. and Venkitasubramanian, T.A. Adenosine 3', 5'-monophosphate in Mycobacterium phlei and Mycobacterium tuberculosis H37Ra. Microbios, 16: 183-
189, 1976 .
140. Padh, H. and Dhariwal, K.R. Cyclic Nucleotides. Science Reporter, 12: 303-308,
Padh, H. and Venkitasubramanian, T. A. Use of enzymes as medicines. J. Health
Sciences: Arogya1
: 101-105, 1975. [IF 0.654]
Projects (handled and ongoing):
Government:
¾ 2012- 2015, Awarded by the Indian Council of Medical Research for Development of vaccine against multidrug resistant shigella dysenteriae type-1 ¾ 2009-, Awarded by the Department of Pharmaceuticals, Government of India,
No.52/137/2008-NIPER for Creation of Incubator Facilities at NIPER - Ahmedabad ¾ 2009- , Awarded by Industries Commissioner, Government of Gujarat,
No.IC/Salt/R&D/09-10/2565 for Centre of Excellence for Quality Assurance of Drugs ¾ 2009- 2011, Awarded by Industries Commissioner, Government of Gujarat ,
No.IC/Salt/R&D/09-10/2574 for Innovative Product Development Platform for SMEs 2009-2011, Awarded by Industries Commissioner, Government of GujaratNo.IC/Salt/R&D/09-10/2568 for Pharma Biotech Incubator Facility 2009-2011, Awarded byIndustries Commissioner, Government of Gujarat,
No.IC/Salt/R&D/09-10/2562 for Biotech Pharma Link Unit for Converting Biological ¾ 2009-2012, Awarded by Department of Pharmaceuticals, Government of India for
Development of novel drug delivery system for treatment of Tuberculosis. ¾ 2007-2012, Awarded by Department of Biotechnology, India for Drug Delivery and Drug ¾ 2007-2010, Awarded by Department of Biotechnology, India for Genetic variation in drug response in Indian population: Correlation between Genotype and Phenotype ¾ 2007- , Awarded by Industries Commissioner, Government of Gujarat To establish Clinical Trials and Data Management for Healthcare Industries ¾ 2006-2009, Awarded by Department of Science & Technology, Government of India for Synthesis and evaluation of Novel Cephalosporins as antibacterial agents ¾ 2000-2001, Awarded by Industries Commissioner, Government of GujaratTo set up Drug ¾ 2000 (April to September), Awarded by UNIDO, Switzerland , for Pharma cluster in Ahmedabad - diagnostics for intervention ¾ 2002-2005, Awarded by Department of Biotechnology, India for Phytochemical evaluation and micropropagation of medicinal plants ¾ 2009-2002, Awarded by Department of Science & Technology, Government of India for Processing of LDL and cardiovascular diseases ¾ 2009-2002, Awarded by Council of Scientific and Industrial Research, for Gene ¾ 2000-2001, Awarded by Industries Commissioner, Government of Gujarat, For Gujarat ¾ 2000-2001, Awarded by Industries Commissioner, Government of Gujarat, To set up ¾ 1998-2000, Awarded by National Dairy Development Board, for Developing Eukaryotic ¾ 1992-1995, Awarded by National Science Foundation (NSF) No. MCB-9113366, for Endocytosis in Dictyostelium: Role of Acidosomes as an Early Endocytic Compartment ¾ 1991-1992, Awarded by National Institutes of Health (NIH) grant No. DK42086, for ¾ 1989-1991, Awarded by Cystic Fibrosis Foundation/University of Chicago, for Chloride channel in acidosomes of Dictyostelium ¾ 1983-1986, Awarded by National Institutes of Health (NIH) grant No. DE 05766, for Vitamin C deficiency in diabetic gingivitis ¾ 1984 (January to December), Awarded for National Institutes of Health (NIH) grant No. RR-5339 for Vitamin C transport in fibroblast Advisor/membership:
¾ Government of Gujarat, on pharmaceuticals and biotechnology matters ¾ Developed proposal and undertook feasibility for Gujarat Biotech Park at Savli ¾ Developed proposal and designing National Centre for Medical Device for NIPER ¾ Developed, designed and run National Institute for Pharmaceutical Education & Research (NIPER) at Ahmedabad, and developing Campus for the same at ¾ On board of advisors for SICART, GIRDA, ACTON Biotech, Vasu Pharma, ¾ Ex- senate member of North Gujarat University (3 years) ¾ Member of the Board of Gujarat Venture Finance Ltd. (BT), Ahmedabad ¾ Gujarat State Biotech Mission (GSBTM) Member of Executive Committee, Governing Body as well as Gujarat State Biotech Council ¾ Steering Committee for NIPERs, Dept. of Pharmaceuticals, Govt. of India (2007-10) ¾ Member of several committees (NBA, AICTE, DCGI etc) ¾ Member: AICTE Western Regional Committee ¾ Member: Indian Pharmacopoeia Working Group ¾ Member: Editorial Board, Indian Journal of Pharmaceutical Sciences and Indian Drugs ¾ Life Member: Society of Biological Chemistry, India ¾ Life Member: Indian Society for Cell Biology. ¾ Life Member: Indian Society for Biomedical Engineering. ¾ Life member: Gujarat Science Academy: American Society for Cell Biology ¾ Member: American Society for Biochemistry & Molecular Biology ¾ Member: DBT, GOI appointed expert member on IBS committees of several pharma ……………………………………………………………………………………………………………

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Cns drugs 2007; 21 (3): 177-184

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