Born in Rome 26/08/1956. Degree in Medicine with laude (1980), Specialty in Endocrinology with laude (1983) and Philosophy Doctor in Endocrinology (1988), University of Rome La Sapienza University Positions and Clinical Activities: 1990-2001. Assistant Professor in Endocrinology, Dept. of Medical Physiopathology, University La Sapienza, Rome-Italy 2002- Associate Professor in Endocrinology, Dept. of Internal Medicine, University Tor Vergata, Rome-Italy 2001- Director UOC of Endocrinology, ASL Roma C - S. Eugenio & CTO A. Alesini Hospital, Rome-Italy Scientific Stages and Positions Abroad: 1982-1983. NIH-NIMH, Bethesda (USA) Dr. C.B. Pert 1984-1989. NIH-NICHD, Bethesda (USA) Dr. M.L. Dufau 1998-2000. Senior Lecturer-Honorary Consultant in Endocrinology, Dept. of Endocrinology, Prof. G.M. Besser, St. Bartholomew's Hospital London Fellowships and scientific prizes: 1983. Wellcome Stipend Fund from FAES 1988. Bracco Prize from SIE for the PhD thesis 1989. Nato-CNR senior fellowship Society memberships: Italian Society of Endocrinology (SIE) - Treasurer, Italian Society of Andrology and Sexual Medicine (SIAMS) - President of Lazio Section European Society Sexual Medicine Endocrine Society Major fields of interest: Male reproduction Adipose tissue Erectile dysfunction Androgens in male aging Osteoporosis Reviewer of the following journals: Journal of Endocrinological Investigation International Journal of Andrology Clinical Endocrinology Endocrinology Journal of Sexual Medicine PlosOne Publications: More than 400 in peer reviewed journals CURRICULUM VITAE – Prof. Andrea FABBRI Professore Associato di Endocrinologia Dipartimento di Medicina Interna, Università di Roma Tor Vergata Direttore UOC Endocrinologia, Polo Ospedaliero Integrato S. Eugenio & CTO A. Alesini, Roma Cell. 338-7126479 Email: andrea.fabbri@uniroma2.it Nato a Roma il 26/08/1956. Maturità classica presso l’Istituto Massimiliano Massimo con 60/60 (1974). Laurea in Medicina e Chirurgia con 110/110 e lode (1980), Università di Roma La Sapienza. Specializzazione in Endocrinologia con 70/70 (1983), Università di Roma La Sapienza. Dottorato di Ricerca in Endocrinologia e Metabolismo (1988), Università di Roma La Sapienza. Posizione Universitaria 1990-2002 Ricercatore, Dip.to Fisiopatologia Medica, Università di Roma La Sapienza 01/11/2002- Professore Associato di Endocrinologia, Università di Roma Tor Vergata Attività Clinico-Assistenziale 1990-2001 Assistente, S.S. di Andrologia, Dipartimento di Fisiopatologia Medica, Università di Roma La Sapienza 1998-2000 Honorary Consultant in Endocrinologia, St. Bartholomew's Hospital, Londra 2002-2003 Aiuto Ambulatorio di Endocrinologia, Policlinico di Tor Vergata, Università di Roma Tor Vergata 2003-2005 Responsabile UOC Endocrinologia, Ospedale Fatebenefratelli, Isola Tiberina, Roma 2006- Direttore UOC di Endocrinologia, Polo Ospedaliero Integrato S. Eugenio e CTO A. Alesini, Roma
Centro di Riferimento Regionale del Lazio Malattie Rare Endocrine
Attività Didattica e Contratti di Insegnamento 1988-89 Titolare del corso: Fisiopatologia della Sessualita' della Facoltà di Medicina, Università La Sapienza. 1989-90 Titolare del corso: Dottrina di Costituzioni Umane di Endocrinologia, ISEF di Roma 1998-2000 Senior Lecturer in Endocrinologia, Dipartimento di Endocrinologia, St. Bartholomew's Hospital, Londra 2001- Professore Associato di Endocrinologia, Università di Roma Tor Vergata 2011-
Esperto del Consiglio Superiore di Sanità
Periodi di lavoro all'estero 1978 Endocrinology Dept., St. Bartholomew's Hospital, Prof. GM. Besser, Londra 1982-83 NIH-NIMH, Bethesda, MD, Section on Brain Biochemistry, Dr. C.B Pert. 1984-89 NIH-NICHD, Bethesda, MD, Section Molecular Endocrinology, Dr. M.L. Dufau 1998-2000 Honorary Consultant e Senior Lecturer in Endocrinologia, St. Bartholomew's Hospital, Londra Borse di Studio e Premi 1983 Wellcome Stipend Fund della FAES 1988 Premio Bracco della Società Italiana di Endocrinologia per la tesi del Dottorato di Ricerca 1989 Borsa NATO-CNR Senior Affiliazioni a Società - Società Italiana di Endocrinologia/SIE (Membro Consiglio Direttivo e Tesoriere) - Endocrine Society - Società Italiana di Andrologia e Medicina della Sessualità/SIAMS (Presidente della Sezione Lazio) Interessi di Ricerca Clinica e Sperimentale -
Disturbi della funzione tiroide/ Obesità/ Osteoporosi
Neuroendocrinologia/ Endocrinologia della riproduzione e dell’età evolutiva/ Malattie rare endocrine
Pubblicazioni scientifiche L'attività scientifica si articola in più di 400 pubblicazioni su riviste, libri ed atti di congresso italiani e stranieri con Impact Factor (IF) attuale di 490. H index = 32 Andrea Fabbri Principali pubblicazioni (2007-2012)
1: Mammi C, Calanchini M, Antelmi A, Cinti F, Rosano GM, Lenzi A, Caprio M, Fabbri A. Androgens and adipose tissue in males: a complex and reciprocal interplay. Int J Endocrinol. 2012:789653. Epub 2011 Dec 22. 2: Minella D, Wannenes F, Biancolella M, Amati F, Testa B, Nardone A, Bueno S, Fabbri A, Lauro D, Novelli G, Moretti C. SOS1 over-expression in genital skin fibroblasts from hirsute women: a putative role of the SOS1/RAS pathway in the pathogenesis of hirsutism. J Biol Regul Homeost Agents. 2011 Oct-Dec;25(4):615-26. 3: Marzolla V, Armani A, Zennaro MC, Cinti F, Mammi C, Fabbri A, Rosano GM, Caprio M. The role of the mineralocorticoid receptor in adipocyte biology and fat metabolism. Mol Cell Endocrinol. 2012 Mar 24;350(2):281-8. Epub 2011 Sep 10. 4: Giganti MG, Minella D, Testa B, Zenobi R, Biancolella M, Isidori AM, Caprio M, Novelli G, Fabbri A. A pilot study on the transcriptional response of androgen- and insulin-related genes in peripheral blood mononuclear cells induced by testosterone administration in hypogonadal men. J Biol Regul Homeost Agents. 2011 Apr-Jun;25(2):291-4. 5: Armani A, Marzolla V, Rosano GM, Fabbri A, Caprio M. Phosphodiesterase type 5 (PDE5) in the adipocyte: a novel player in fat metabolism? Trends Endocrinol Metab. 2011 Oct;22(10):404-11. Epub 2011 Jul 7 6: Mammi C, Pastore D, Lombardo MF, Ferrelli F, Caprio M, Consoli C, Tesauro M, Gatta L, Fini M, Federici M, Sbraccia P, Donadel G, Bellia A, Rosano GM, Fabbri A, Lauro D. Sildenafil reduces insulin-resistance in human endothelial cells. PLoS One. 2011 Jan 28;6(1):e14542. 7: Franconi G, Manni L, Aloe L, Mazzilli F, Giambalvo Dal Ben G, Lenzi A, Fabbri A. Acupuncture in clinical and experimental reproductive medicine: a review. J Endocrinol Invest. 2011 Apr;34(4):307-11. Epub 2011 Feb 4. 8: Aversa A, Caprio M, Antelmi A, Armani A, Brama M, Greco EA, Francomano D, Calanchini M, Spera G, Di Luigi L, Rosano GM, Lenzi A, Migliaccio S, Fabbri A. Exposure to phosphodiesterase type 5 inhibitors stimulates aromatase expression in human adipocytes in vitro. J Sex Med. 2011 Mar;8(3):696-704. 9: Caprio M, Antelmi A, Chetrite G, Muscat A, Mammi C, Marzolla V, Fabbri A, Zennaro MC, Fève B. Antiadipogenic effects of the mineralocorticoid receptor antagonist drospirenone: potential implications for the treatment of metabolicsyndrome. Endocrinology. 2011 Jan;152(1):113-25. Epub 2010 Nov 17.
10: Mariani S, Basciani S, Fabbri A, Agati L, Ulisse S, Lubrano C, Spera G, Gnessi L. Severe oligozoospermia in a young man with chronic myeloid leukemia on long-term treatment with imatinib started before puberty. Fertil Steril. 2011 Mar 1;95(3):1120.e15-7. 11: Lenzi A, Balercia G, Bellastella A, Colao A, Fabbri A, Foresta C, Galdiero M, Gandini L, Krausz C, Lombardi G, Lombardo F, Maggi M, Radicioni A, Selice R, Sinisi AA, Forti G. Epidemiology, diagnosis, and treatment of male hypogonadotropic hypogonadism. J Endocrinol Invest. 2009 Dec;32(11):934-8. Epub 2009 Dec 1. 12: Jannini EA, Isidori AM, Gravina GL, Aversa A, Balercia G, Bocchio M, Boscaro M, Carani C, Corona G, Fabbri A, Foresta C, Forti G, Francavilla S, Granata AR, Maggi M, Mansani R, Palego P, Spera G, Vetri M, Lenzi A; Endotrial Study Group. The ENDOTRIAL study: a spontaneous, open-label, randomized, multicenter, crossover study on the efficacy of sildenafil, tadalafil, and vardenafil in the treatment of erectile dysfunction. J Sex Med. 2009 Sep;6(9):2547-60. Epub 2009 Jun 29. 13: Trento LK, Pietropolli A, Ticconi C, Gravotta E, De Martino MU, Fabbri A, Piccione E. Role of type I collagen C telopeptide, bone-specific alkaline phosphatase and osteocalcin in the assessment of bone status in postmenopausal women. J Obstet Gynaecol Res. 2009 Feb;35(1):152-9. 14: Caprio M, Mammi C, Jaffe IZ, Zennaro MC, Aversa A, Mendelsohn ME, Fabbri A, Rosano GM. The mineralocorticoid receptor in endothelial physiology and disease: novel concepts in the understanding of erectile dysfunction. Curr Pharm Des. 2008;14(35):3749-57. 15: Foresta C, Caretta N, Corona G, Fabbri A, Francavilla S, Jannini E, Maggi M, Bettocchi C, Lenzi A. Clinical and metabolic evaluation of subjects with erectile dysfunction: a review with a proposal flowchart. Int J Androl. 2009 Jun;32(3):198-211. Epub 2008 Dec 9. 16: Wannenes F, Caprio M, Gatta L, Fabbri A, Bonini S, Moretti C. Androgen receptor expression during C2C12 skeletal muscle cell line differentiation. Mol Cell Endocrinol. 2008 Sep 24;292(1-2):11-9. Epub 2008 Jun 7. 17: Caprio M, Zennaro MC, Fève B, Mammi C, Fabbri A, Rosano G. Potential role of progestogens in the control of adipose tissue and salt sensitivity via interaction with the mineralocorticoid receptor. Climacteric. 2008 Jun;11(3):258-64. 18: Caprio M, Newfell BG, la Sala A, Baur W, Fabbri A, Rosano G, Mendelsohn ME, Jaffe IZ. Functional mineralocorticoid receptors in human vascular endothelial cells regulate intercellular adhesion molecule-1 expression and promote leukocyte adhesion. Circ Res. 2008 Jun 6;102(11):1359-67. Epub 2008 May 8
19: Shabsigh R, Arver S, Channer KS, Eardley I, Fabbri A, Gooren L, Heufelder A, Jones H, Meryn S, Zitzmann M. The triad of erectile dysfunction, hypogonadism and the metabolic syndrome. Int J Clin Pract. 2008 May;62(5):791-8. Epub 2008 Feb 2. 20: Shabsigh R, Arver S, Channer KS, Eardley I, Fabbri A, Gooren L, Heufelder A, Jones H, Meryn S, Zitzmann M. Sexual health as a portal to men's health: a problem turned around into an opportunity. Int J Clin Pract. 2008 Feb;62(2):179-81. 21: Aversa A, Vitale C, Volterrani M, Fabbri A, Spera G, Fini M, Rosano GM. Chronic administration of Sildenafil improves markers of endothelial function in men with Type 2 diabetes. Diabet Med. 2008 Jan;25(1):37-44. 22: Fabbri A, Giannetta E, Lenzi A, Isidori AM. Testosterone treatment to mimic hormone physiology in androgen replacement therapy. A view on testosterone gel and other preparations available. Expert Opin Biol Ther. 2007 Jul;7(7):1093-106.
Artikel des Monats Blumenthal, J.A., et al., Exercise and pharmacotherapy in the treatment of major depressive disorder. Psychosom Med, 2007. 69 (7): p. 587-96. DOI: 10.1097/PSY.0b013e318148c19a OBJECTIVE: To assess whether patients receiving aerobic exercise training performed either at home or in a supervised group setting achieve reductions in depression comparable to standard antidepressa
Eili Klein,* David L. Smith,† and Ramanan Laxminarayan* Hospital-acquired infections with Staphylococcus au- increased, fi rst to other hospitals and then into the commu- reus , especially methicillin-resistant S. aureus (MRSA) in-nity ( 5 ). By the late 1960s, >80% of community- and hos-fections, are a major cause of illness and death and impose pital-acquired S . aureus isolat