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NOTA CLINICA Embriopatía por isotretinoína. A propósito de una observación Introducción La isotretinoína es conocida desde hace años como uno de losteratógenos más potentes en humanos(1). Su uso terapéutico en adul-tos está limitado a casos de acné resistente, psoriasis e ictiosis. Serecomienda que no sea utilizada por mujeres en edad fértil y que,en cualquier caso, se e