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Ms fatigue

F A T I G U E A N D M U L T I P L E S C L E R O S I S Table 2. Medications Prescribed to MS Patients that Cause Fatigue*
This information was derived from the 1998 Physicians’ Desk quent”, olanzapine (Zyprexa)++, risperidone Reference (Medical Economics, Inc.), unless otherwise stated.
Agents are cited that cause symptoms in >5% of patients. The rate Asthma drugs
is indicated by the “+” sign (+ = 5-10%, ++ = 10-25%, +++ = 25- fluticasone (Flovent) +++, terbutaline ++ 50%, ++++ = >50%). When a range was given “e.g., 5-11%,”the number of “+s” corresponds to the highest number.
Carbonic anhydrase inhibitors
dichlorphenamide (Daranide) “among the most com- Analgesics
butalbital “among most frequent”, butorphanol (StadolNS) +++, dihydrocodeine “among the most frequent”, fentanyl (Duragesic transdermal)++, hydrocodone bepridil (Vascor)++, amiodurone (Cordarone)+, disopy- (Vicoprofen)+, morphine “among frequent”, oxycodone ramide (Norpace)+, flecainide (Tambocor) +, nifedipine (Procardia)++, quinine (Cardioquin, Quinidex)+, satolol Anticonvulsants
Diabetic agents
carbamazepine (Tegretol) “among most common”, c h l o- glipizide (Glucotrol)++, troglitazone (Rezulin)+ razepate (Tranxene) “most frequent”, divalpro e x Gastrointestinal
(Depakote) +++, felbamate (Felbatol) +++, gabapentin Bentyl +, granisetron (Kytril)++, metoclopramide (Neurontin) ++, lamotrigine (Lamictal)++, phenobarbital “can develop during therapy”1, primidone (Mysoline) Genitourinary
Antidepressants
Hormone replacement
buspirone (Buspar) ++, clomipramine (Anafranil) ++++, Depo-Provera (medroxyprogresterone)+, progesterone cream (Crinone)+++, leuprolide (Lupron)+ (Lupron fluoxetine (Prozac) ++, fluvoxamine (Luvox) ++, mir- tazapine (Remeron) ++++, nephazodone (Serzone)+++, paroxetine (Paxil) ++, sertraline (Zoloft)++, tra- Immune modulators
zodone (Desyrel) +++, tricyclic agents “most interferon beta-1a (Avonex) ++, interferon beta-1b f re q u e n t”1, venlafaxine (Effexor) +++ Antihistamines
Muscle relaxants
astemizole (Hismanal)+, azatedine (Trinalin) “among carisoprodal (Soma) “most frequent”, cyclobenzaprine most frequent”, azelastine (Astelin)++, cetirizine (Flexeril) +++, dantrolene (Dantrium) “among the most (Zyrtec)++, chlorpheniramine “among most common”, frequent”, diazepam (Valium) “among the most com- diphenhydramine “among most frequent”, loratadine (Claritin)+, phenylephrine “among most common”, ter- Nicotine agents
Habitrol +, Nicotrol Nasal Spray +, Prostep+ Antihypertensive
Sedative hypnotics
acebutolol (Sectral) ++, amiloride (Moduretic) +, alprazolam (Xanax) ++++, clonazepam (Klonopin)+++, atenolol (Tenoretic, Tenormin)+++, benzapril diazepam (Valium) “among the most common,” estazo- (Lotensin)+, betaxolol (Kerlone)+, carteolol (Cartrol)+, lam (ProSom)+++, quazapam (Doral)++, secobarbital clonidine (Catapres, Combipress)+++, diltiazem “most common”, temazepam (Restoril) ++ , triazolam guanadrel (Hylorel) ++++, guanfacine (Tenex) ++, labatelol (Normodyne, Trandate)+, metroprolol dexfenfluramine (Redux)++, fenfluramine (Pondimin) (Lopressor, Toprol)+, nifedipine (Adalat)++, perindopril “among most common”, scopolamine (Transderm (Aceon)+, prazosin (Minipress, Minizide)+ Anti-inflammatory
fenoprofen (Nalfon)+, ketorolac (Toradol)+, naproxen(Anaprox, Naprelan, Naprosyn), tolmetin (Tolectin)+ Antipsychotic
clozapine (Clozaril)+++, mesoridazine (Serentil) “oneof the 2 most prevalent,” molindone (Moban) “most fre- * “Fatigue,” “weakness” (“asthenia”), “somnolence,” and “lethargy.” 11994-1997 Gold Standard Multimedia, Inc.
From: Fatigue and MS: Evidence-Based Management Strategies for Fatigue in MS at http://www.mscare.org/cmsc/images/pdf/pdf/fatigue.pdf

Source: http://hablemosdeem.com/desdemibalcon/wp-content/uploads/2010/07/Table-2-Fatigue-Medicines.pdf

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