PRODUCT DATA SHEET www.bioviotica.com BVT-0246 Ansatrienin A Handling / Storage
Protect from light when in solution. Use / Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
MSDS available at www.adipogen.com or upon request. Product Specifications
Isolated from Streptomyces collinus.
Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO. Product Description
• Inhibits osteoclastic bone resorption. WARNING: Intended for research use only. This product is not intended or approved for human, diagnostics, therapeutic or veterinary use. Use of this product for human or animal testing is extremely hazardous and may result in disease, severe injury, or death. MATERIAL SAFETY DATA: Review the complete Material Safety Data Sheet before use. BioViotica Naturstoffe GmbH BioViotica Naturstoffe GmbH For Local Distributors see PRODUCT DATA SHEET www.bioviotica.com Product Specific References
1. Mycotrienin, a new polyene antibiotic isolated from Streptomyces: C. Coronelli, et al.; J. Antibiot. (Tokyo)
20, 329 (1967)
2. Die Konstitution der fungistatischen Ansamycin-Antibiotica Ansatrienin A und B: M. Damberg, et al.; Tetra-
hedron Lett. 23, 59 (1982)
3. Studies on mycotrienin antibiotics, a novel class of ansamycins. I. Taxonomy, fermentation, isolation and
properties of mycotrienins I and II: M. Sugita, et al.; J. Antibiot. (Tokyo) 35, 1460 (1982)
4. Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of
mycotrienins I and II: M. Sugita, et al.; J. Antibiot. (Tokyo) 35, 1467 (1982)
5. Potentiation of mitomycin C, 6-mercaptopurine, bleomycin, cis-diamminedichloroplatinum and 5-fluorouracil
by mycotrienins and mycotrienols: M. Kuwano, et al.; Gann. 74, 759 (1983)
6. Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption: D. Feuerbach, et al.; J. Biol.
Chem. 270, 25949 (1995)
7. (+)-trienomycin A, B, C, and F and (+)-mycotrienins I and II: relative and absolute stereochemistry: A. B.
Smith, et al.; JACS 118, 8308 (1996)
8. Total syntheses of (+)-trienomycins A and F via a unified strategy: A. B. Smith, et al.; JACS 118, 8316 (1996)
9. Total synthesis of (+)-mycotrienol and (+)-mycotrienin I: application of asymmetric crotylsilane bond construc-
tions: C. E. Masse, et al.; JACS 120, 4123-4134 (1998) WARNING: Intended for research use only. This product is not intended or approved for human, diagnostics, therapeutic or veterinary use. Use of this product for human or animal testing is extremely hazardous and may result in disease, severe injury, or death. MATERIAL SAFETY DATA: Review the complete Material Safety Data Sheet before use. BioViotica Naturstoffe GmbH BioViotica Naturstoffe GmbH For Local Distributors see
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