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Material Safety Data Sheet
Section 1: Chemical Product and Company Identification
14025 Smith Rd.
US Sales: 1-800-901-7247
International Sales: 1-281-441-4400
TSCA 8(b) inventory: No products were found.
CHEMTREC (24HR Emergency Telephone), call:
Losec; Pepticum; Ulceral; Antra; Aulcer;
International CHEMTREC, call:
For non-emergency assistance, call:
Section 2: Composition and Information on Ingredients
% by Weight
Toxicological Data on Ingredients:
Omeprazole: ORAL (LD50): Acute: >4000 mg/kg [Mouse]. 2210 mg/kg [Rat].
Section 3: Hazards Identification
Potential Acute Health Effects:
Hazardous in case of inhalation (lung irritant). Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available. The substance may be toxic to gastrointestinal tract. Repeated or prolonged
exposure to the substance can produce target organs damage.
Section 4: First Aid Measures
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Cold water may be used. WARM water MUST be used. Get medical attention.
In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated
clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
Serious Skin Contact:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.
Section 5: Fire and Explosion Data
Flammability of the Product:
May be combustible at high temperature.
Products of Combustion:
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2.).
Fire Hazards in Presence of Various Substances:
Slightly flammable to flammable in presence of heat. Non-flammable in presence of shocks.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in
presence of static discharge: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards:
Special Remarks on Explosion Hazards:
Section 6: Accidental Release Measures
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on
the contaminated surface and dispose of according to local and regional authority requirements.
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the
contaminated surface and allow to evacuate through the sanitary system.
Section 7: Handling and Storage
Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a
fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. If ingested, seek medical advice
immediately and show the container or the label. Keep away from incompatibles such as oxidizing agents.
Moisture sensitive. Keep container tightly closed. Keep container in a cool, well-ventilated area. Preferably freeze (Store
between -25°C (-13°F) and -30 C). Otherwise, keep refrigerated.
Section 8: Exposure Controls/Personal Protection
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended
exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants
below the exposure limit.
Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves (impervious).
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this
Section 9: Physical and Chemical Properties
Physical state and appearance:
Solid. (Crystals solid. Crystalline solid.)
pH (1% soln/water):
Water/Oil Dist. Coeff.:
The product is more soluble in oil; log(oil/water) = 2.2
Ionicity (in Water):
See solubility in water, methanol, acetone.
Easily soluble in methanol. Partially soluble in acetone. Very slightly soluble in cold water, hot water.
Section 10: Stability and Reactivity Data
The product is stable.
Conditions of Instability:
Elevated temperatures, moisture, incompatible materials
Incompatibility with various substances:
Reactive with oxidizing agents.
Special Remarks on Reactivity:
Special Remarks on Corrosivity:
Will not occur.
Section 11: Toxicological Information
Routes of Entry:
Toxicity to Animals:
Acute oral toxicity (LD50): 2210 mg/kg [Rat].
Chronic Effects on Humans:
May cause damage to the following organs: gastrointestinal tract.
Other Toxic Effects on Humans:
Hazardous in case of inhalation (lung irritant). Slightly hazardous in case of skin contact (irritant), of ingestion, .
Special Remarks on Toxicity to Animals:
Special Remarks on Chronic Effects on Humans:
May cause adverse reproductive effects based on animal data. May affect genetic material. May cross the placenta.
Special Remarks on other Toxic Effects on Humans:
Acute Potential Health Effects: Skin: May cause skin irritation. Eyes: Dust may cause eye irritation. Inhalation: Dust may cause
respiratory tract irritation. Ingestion: May cause digestive tract irritation with nausea, vomiting, hypermotility, and diarrhea.
May also affect, blood (Eosinophilia, Normocytic anemia), metabolism, brain, behavior (ataxia, convulsions, sedation, change
in motor activity, decreased activity), respiration (dyspnea, coughing, decreased respiration, plerual effusion, ptosis), liver
(jaundice, hepatitis), immune system, urinary system/kidneys, and cause musculoskeletal effects.
Section 12: Ecological Information
BOD5 and COD:
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation:
The product itself and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation:
Section 13: Disposal Considerations
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
Not a DOT controlled material (United States).
Special Provisions for Transport:
Section 15: Other Regulatory Information
Federal and State Regulations:
No products were found.
Not controlled under WHMIS (Canada).
R36/37/38- Irritating to eyes, respiratory system and skin. S26- In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. S36- Wear suitable protective clothing.
National Fire Protection Association (U.S.A.):
Gloves (impervious). Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses.
Section 16: Other Information
Other Special Considerations:
10/10/2005 11:05 AM
11/06/2008 12:00 PM
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