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Material Safety Data Sheet
Omeprazole MSDS
Section 1: Chemical Product and Company Identification
Product Name: Omeprazole
Contact Information:
Catalog Codes: SLO1468
Sciencelab.com, Inc.
14025 Smith Rd.
CAS#: 73590-58-6
RTECS: DD9087000
US Sales: 1-800-901-7247
International Sales: 1-281-441-4400
TSCA: TSCA 8(b) inventory: No products were found.
CI#: Not available.
CHEMTREC (24HR Emergency Telephone), call:
Synonym: Losec; Pepticum; Ulceral; Antra; Aulcer;
International CHEMTREC, call: 1-703-527-3887
Chemical Name: Omeprazole
For non-emergency assistance, call: 1-281-441-4400
Chemical Formula: C17-H19-N3-O3-S
Section 2: Composition and Information on Ingredients
Composition:
% by Weight
Toxicological Data on Ingredients: Omeprazole: ORAL (LD50): Acute: >4000 mg/kg [Mouse]. 2210 mg/kg [Rat].
Section 3: Hazards Identification
Potential Acute Health Effects:
Hazardous in case of inhalation (lung irritant). Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of
ingestion, .
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available. The substance may be toxic to gastrointestinal tract. Repeated or prolonged
exposure to the substance can produce target organs damage.
Section 4: First Aid Measures
Eye Contact:
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Cold water may be used. WARM water MUST be used. Get medical attention.
Skin Contact:
In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated
clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
Serious Skin Contact: Not available.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention.
Serious Inhalation: Not available.
Ingestion:
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.
Serious Ingestion: Not available.
Section 5: Fire and Explosion Data
Flammability of the Product: May be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Flash Points: Not available.
Flammable Limits: Not available.
Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2.).
Fire Hazards in Presence of Various Substances:
Slightly flammable to flammable in presence of heat. Non-flammable in presence of shocks.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in
presence of static discharge: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
Section 6: Accidental Release Measures
Small Spill:
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on
the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill:
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the
contaminated surface and allow to evacuate through the sanitary system.
Section 7: Handling and Storage
Precautions:
Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a
fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. If ingested, seek medical advice
immediately and show the container or the label. Keep away from incompatibles such as oxidizing agents.
Storage:
Moisture sensitive. Keep container tightly closed. Keep container in a cool, well-ventilated area. Preferably freeze (Store
between -25°C (-13°F) and -30 C). Otherwise, keep refrigerated.
Section 8: Exposure Controls/Personal Protection
Engineering Controls:
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended
exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants
below the exposure limit.
Personal Protection:
Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves (impervious).
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this
product.
Exposure Limits: Not available.
Section 9: Physical and Chemical Properties
Physical state and appearance: Solid. (Crystals solid. Crystalline solid.)
Odor: Not available.
Taste: Not available.
Molecular Weight: 345.42 g/mole
Color: Off-white. White.
pH (1% soln/water): Not available.
Boiling Point: Not available.
Melting Point: 156°C (312.8°F)
Critical Temperature: Not available.
Specific Gravity: Not available.
Vapor Pressure: Not applicable.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff.: The product is more soluble in oil; log(oil/water) = 2.2
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water, methanol, acetone.
Solubility:
Easily soluble in methanol. Partially soluble in acetone. Very slightly soluble in cold water, hot water.
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Elevated temperatures, moisture, incompatible materials
Incompatibility with various substances: Reactive with oxidizing agents.
Corrosivity: Not available.
Special Remarks on Reactivity: Moisture sensitive
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Inhalation. Ingestion.
Toxicity to Animals: Acute oral toxicity (LD50): 2210 mg/kg [Rat].
Chronic Effects on Humans: May cause damage to the following organs: gastrointestinal tract.
Other Toxic Effects on Humans:
Hazardous in case of inhalation (lung irritant). Slightly hazardous in case of skin contact (irritant), of ingestion, .
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans:
May cause adverse reproductive effects based on animal data. May affect genetic material. May cross the placenta.
Special Remarks on other Toxic Effects on Humans:
Acute Potential Health Effects: Skin: May cause skin irritation. Eyes: Dust may cause eye irritation. Inhalation: Dust may cause
respiratory tract irritation. Ingestion: May cause digestive tract irritation with nausea, vomiting, hypermotility, and diarrhea.
May also affect, blood (Eosinophilia, Normocytic anemia), metabolism, brain, behavior (ataxia, convulsions, sedation, change
in motor activity, decreased activity), respiration (dyspnea, coughing, decreased respiration, plerual effusion, ptosis), liver
(jaundice, hepatitis), immune system, urinary system/kidneys, and cause musculoskeletal effects.
Section 12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation: Not available.
Section 13: Disposal Considerations
Waste Disposal:
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
DOT Classification: Not a DOT controlled material (United States).
Identification: Not applicable.
Special Provisions for Transport: Not applicable.
Section 15: Other Regulatory Information
Federal and State Regulations: No products were found.
Other Regulations: Not available.
Other Classifications:
WHMIS (Canada): Not controlled under WHMIS (Canada).
DSCL (EEC):
R36/37/38- Irritating to eyes, respiratory system and skin. S26- In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. S36- Wear suitable protective clothing.
HMIS (U.S.A.):
Health Hazard: 1
Fire Hazard: 1
Reactivity: 0
Personal Protection: E
National Fire Protection Association (U.S.A.):
Health: 1
Flammability: 1
Reactivity: 0
Specific hazard:
Protective Equipment:
Gloves (impervious). Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses.
Section 16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 10/10/2005 11:05 AM
Last Updated: 11/06/2008 12:00 PM
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Source: http://www.westernu.org/bin/safety/msds/hpc/Omeprazole.pdf

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