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Chairs:
Selim Badur
Professor, Department of Microbiology, Division of Virology and Immunology, Istanbul University Medical School, Istanbul, Turkey Director, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA Professor of Medicine and Stuart S. Richardson Professor of Clinical Virology, University of Virginia School of Medicine, Charlottesville, Virginia, USA; Influenza Research Coordinator, The Wellcome Trust, London, United Kingdom Thomas Francis Jr Professor of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA Professor of Virology, Erasmus MC, Rotterdam, The Netherlands
Scientific Advisory Board:

Rick Bright
Biomedical Advance Research and Development Authority, Washington, DC, USA confirmed Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey confirmed Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands confirmed University of Tennessee, Memphis, Tennessee, USA confirmed National Heart & Lung Institute, Imperial College, London, United Kingdom confirmed University of Tokyo, Tokyo, Japan; University of Wisconsin, Madison Wisconsin, USA; University of Tokyo, Tokyo, Japan confirmed Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China confirmed Vanderbilt University School of Medicine, Nashville, Tennessee, USA confirmed Armed Forces Health Surveillance Center, Silver Springs, Maryland, USA confirmed Infectious Diseases, University of Singapore Hospital, Singapore confirmed

Day One
Friday, 23 March 2012
Registration Desk Opens
Welcome – Cathryn Macrae, The Macrae Group LLC, and The Macrae Foundation confirmed Keynote Address – Risk Assessment of New Emerging Novel Respiratory Viruses…. - Nancy Cox, Director, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA confirmed
Session I
Minisymposium: Animal/Human Interface – Chair: Albert
Osterhaus, Professor of Virology, Erasmus MC, Rotterdam, The
Netherlands

The Role of Birds in Pandemic Influenza – Giovanni Cattoli, Istituto Zooprofilattico Sperimentale delle Venezie, Padova, Italy confirmed The Role of Swine Influenza – Richard Webby, Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, USA confirmed New Viral Pathogens Discoveries in Bats – Christian Drosten, Clinical Virology Section, Bernhard-Nocht-Institut, Hamburg, Germany invited Oral Presentation
Rates and Patterns of Genomic Reassortment of Influenza Viruses in North American Swine – Martha Nelson, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of American confirmed Oral Presentation - Young Investigator Award Recipient Sponsored
by The Macrae Group LLC

Cross-species Transmission of Pandemic Influenza (pH1N1) Virus in Backyard Pig Farms in Semirural Communities in Tumbes, Peru – Yeny Tinoco, US Naval Medical Research Unit – Six, Lima, Perú confirmed
Session II
Virology/Diagnostics –Chair: Malik Peiris, Department of
Microbiology, University of Hong Kong, Hong Kong SAR, China


12.10 – 12.35
Multi- Respiratory Diagnostic Platform – TBD Paramyxovirus Virus: A Never-Ending Story – Albert Osterhaus, Professor of Virology, Erasmus MC, Rotterdam, The Netherlands confirmed Novel Diagnostic Technologies – David Murdoch, University of Otago, Christchurch, New Zealand confirmed 15.20 – 15.40 –New Generation PCR under Multiplex Assays - David Ecker, Ibis Biosciences,an Abbott Company, Carlsbad, California, United States confirmed 15.40 – 16.00 – Molecular Diagnostics Assays – Karen Young, Roche Molecular Systems, Inc., Pleasanton, CA, United States invited Oral Presentation - Young Investigator Award Recipient Sponsored
by The Macrae Group LLC

Characterization of the Fitness Impairments Induced by the H275Y Oseltamivir-resistance Mutation in the Influenza A/Brisbane/59/2007 and 2009 Pandemic H1N1 Backgrounds – Catherine Beauchemin, Ryerson University, Toronto, Canada confirmed Oral Presentation
Detection of Viruses by Real Time RT-PCR in Children with Acute Respiratory Tract Infection (ARI) from a Rural Community in India – Shobha Broor, All India Institute of Medical Sciences, Delhi, India Oral Presentation - Young Investigator Award Recipient Sponsored
by The Macrae Group LLC

Detection of Polymorphisms at Residue 222 of the Pandemic Influenza A/H1N1 Hemagglutinin at Quasi-species Level: Association with Severe Cases – Paola Cristina Resende, Laboratory of Respiratory Viruses and Measles, Oswaldo Cruz Institute, Rio de Janeiro, Brasil confirmed
Session III
Pathogenesis – Chair: Yoshihiro Kawaoka, University of Wisconsin,
Madison Wisconsin, USA; University of Tokyo, Tokyo, Japan


16.45 – 17.05
Literature Review – Pre-Clinical SARS and Influenza - Malik Peiris, Department of Microbiology, University of Hong Kong, Hong Kong SAR, China confirmed Literature Review – Pre-Clinical Rhinovirus and other Respiratory Viruses - Sebastian Johnston, National Heart & Lung Institute, Imperial College, London, United Kingdom confirmed Measles Immune Suppression: Lessons from the Macaque Model– Rik De Swart, Erasmus MC, Department of Virology, Rotterdam, The Netherlands confirmed
18.00 – 19.30
Welcome Reception
Saturday 24 March 2012

Session III
Pathogenesis – Chair: Yoshihiro Kawaoka, University of Wisconsin,
Madison Wisconsin, USA; University of Tokyo, Tokyo, Japan

(continued)
New Insights from Studies on Influenza –Yoshi Kawaoka, University of Tokyo, Tokyo, Japan; University of Wisconsin, Madison, Wisconsin, USA confirmed Immunopathogenesis Implications for RSV – Fernando Polack, Division of Infectious Disease, Vanderbilt University School of Medicine, Nashville, Tennessee, USA confirmed Surprise H5N1 – Sander Herfst, Department of Virology, Erasmus MC, Rotterdam, The Netherlands confirmed Oral Presentation
The PB1-F2 Protein Proapoptotic Sequence Contributes to Influenza A Virus Pathogenicity and Predisposition to Secondary Bacterial Infection – Irina V. Alymova, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America confirmed Oral Presentation
The Influence of Smoking on Pulmonary Influenza Infection – an Ex vivo Study John M. Nicholls, The University of Hong Kong, Pok Fu Lam, Hong Kong confirmed Oral Presentation
Deficient Antiviral Responses to Influenza in Primary Bronchial Epithelial Cells of Chronic Obstructive Pulmonary Disease – Peter AB Wark, Centre for Asthma and Respiratory Disease, Hunter Medical Research Institute, University of Newcstle, New South Wales, Australia
Session IV
Epidemiology/Impact – Chair: Arnold Monto, Thomas Francis Jr
Professor of Epidemiology, University of Michigan, Ann Arbor,
Michigan, USA

Special Invited Lecture: Lessons Learned from H1N1 Pandemic – Sylvie Briand, Influenza, Respiratory Diseases, Hepatitis, PIP framework (IRD/PED) Health Security and Environment (HSE), World Health Organization, Geneva, Switzerland Coffee Break
Burden of Disease of Respiratory Viral Infections, a Geographical Prospective – W. Abdullah Brooks, Director Kamalapur Field Site, Head Infectious Diseases Unit (ICDDR,B), Johns Hopkins Bloomburg School of Public Health, Dhaka, Bangladesh and Baltimore, Maryland, USA confirmed Estimating the Global Impact of Influenza - Marc Alain Widdowson, Division of Viral Disease, Center for Disease Control, Atlanta, Georgia, USA confirmed
13.05 - 15.05
Lunch Break
Importance of Respiratory Viral Diseases in Turkey – Selim Badur, Department of Microbiology, Division of Virology and Immunology, Istanbul University Medical School, Istanbul, Turkey confirmed Burden of RSV in the Elderly – Ann Falsey, University of Rochester, Rochester, New York, USA confirmed Oral Presentation
The Role of Respiratory Viruses in Lower Respiratory Tract Infections in Primary Care – Frank E. J. Coenjaerts, University Medical Center Utrecht, The Netherlands confirmed Oral Presentation
Respiratory Viruses in Airline Travelers with Influenza Symptoms: Results of an Airport Screening Study – Lance C. Jennings, Canerbury Health Laboratories, University of Otago, Christchurch, New Zealand Oral Presentation
Molecular Epidemiology of Adenovirus 4 and 7 Infections of Military Recruits in Training during the 15 Years with no Vaccination Program (1997-2011) – Adriana Kajon, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA confirmed Oral Presentation
A Retrospective, Observational Study on Incidence, Influenza-Associated Complications, and Treatment Patterns of Influenza in the United States: 2006–2010 Influenza Seasons – Philip Spagnuolo, Genentech, Inc., South San Francisco, California, USA confirmed Oral Presentation
Spatial Epidemiology of Respiratory Syncytial Virus (RSV) in the USA – Cécile Viboud, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA Poster Review - Albert Osterhaus, Erasmus MC, Rotterdam, The Netherlands confirmed Wine/Cheese Reception & Poster Session

Day Three

Sunday, 25 March 2012

Session V
Clinical – Frederick Hayden, Professor of Medicine and Stuart S.
Richardson Professor of Clinical Virology, University of Virginia
School of Medicine, Charlottesville, Virginia, USA; Influenza
Research Coordinator, The Wellcome Trust, London, United
Kingdom

Literature Review: Clinical Papers Adults + discussion– Frederick Hayden, Professor of Medicine and Stuart S. Richardson Professor of Clinical Virology, University of Virginia School of Medicine, Charlottesville, Virginia, USA; Influenza Research Coordinator, The Wellcome Trust, London, United Kingdom confirmed Literature Review: Clinical Papers Children + discussion – Susanna Esposito, Department of Maternal and Pediatric Sciences, University of Milan, Milan, Italy confirmed Severe Manifestation of H1N1 – Jordi Rello, Critical Care Department, University Hospital Vall d’Hebron, Barcelona, Spain confirmed
10.30 – 11.00
Coffee Break
Session VI
Antivirals and Therapeutics – Chair: Menno de Jong, Academic
Medical Center, University of Amsterdam, Amsterdam, The
Netherlands

Antivirals for Respiratory Viruses Overview – Menno de Jong, University of Amsterdam, The Netherlands confirmed RNA Interference Strategies for Respiratory Virus Infection – John DeVincenzo, University of Tennessee, Memphis, Tennessee, USA confirmed Respiratory Viral Infections- Monoclonal Antibodies – TBD Oral Presentation
The Influenza Resistance Information Study (IRIS): Patterns and Predictors of Antiviral Drug Treatment – Drew GriffinLevy, Genentech, South San Francisco, California, USA Oral Presentation
A Systematic Review on the Impact of Neuraminidase Inhibitor Antiviral use on Outcomes of Public Health Importance during the 2009/10 (Swine) Pandemic Influenza A/H1N1v – Stella Muthuri, University of Nottingham, United Kingdom confirmed Oral Presentation
Clinical and Virological Response to Oseltamivir in Infants <1 year with Influenza Barbara Rath, Charité University Medical Center, Berlin, Germany confirmed Symposium Adjourns for the Day – free afternoon and evening
Monday, 26 March 2012

Session VI

Antivirals and Therapeutics – Chair: Menno de Jong, Academic
Medical Center, University of Amsterdam, Amsterdam, The
Netherlands (continued)


09.00 – 09.15
Oral Presentation
Macrolides and Anti-Inflammatory Agents in the Treatment of Avian Influenza (H5N1) – Stephen Toovey, Academic Centre for Travel Medicine & Vaccines, Royal Free and University College Medical School, London, United Kingdom Oral Presentation
Pharmacokinetic-pharmacodynamic (PK-PD) determinants of oseltamivir efficacy using data from two Phase 2 inoculation studies – Craig Rayner, Roche Products Pty Ltd, South Melbourne, Australia
Session VII
Vaccinology/Prevention – Chair: Nancy Cox, Director, Influenza
Division, National Center for Immunization and Respiratory
Diseases, Centers for Disease Control and Prevention, Atlanta,
Georgia, USA

New Vaccines for Respiratory Virus Infections – Adolfo Garcia-Sastre, Mt Sinai School of Medicine, New York, New York, USA confirmed How do we Deal with Guillian-Barre Syndrome, Narcolepsy and Other Adverse Events Post Vaccination – David Salisbury, Director of Immunisation, Department of Health, London, United Kingdom confirmed Update on Novel Influenza Vaccines from the WHO Meeting – Rick Bright, Influenza Division, Biomedical Advanced Research and Development Authority (BARDA), Office of the Assistant Secretary for Preparedness and Response, U.S. Department of Health and Human Services, Washington, D.C. confirmed
10.45 – 11.00
Oral Presentation
A Novel RSV Genetic Vaccine Candidate based on Chimpanzee Adenovirus and MVA Vectors is Safe and Highly Immunogenic in Rodents and Primates and fully Protects Cotton Rats from RSV Challenge – Alessandra Vitelli, Okairos Srl, Pomezia, Rome, Italy confirmed Oral Presentation
Monoclonal Antibodies Cross-reacting with the Neuraminidase of Seasonal and 2009 Pandemic H1N1 Influenza Viruses – Hongquan Wan, Laboratory of Respiratory Viral Diseases, US Food and Drug Administration, Bethesda, Maryland, United States of America Oral Presentation
Efficacy of Seasonal Influenza Vaccination in Children in Hong Kong: a Randomized Controlled Trial – Benjamin J. Cowling, School of Public Health, The University of Hong Kong, Pokfulam, Hong Kong Oral Presentation
Safety and Immunogenicity of a Recombinant RSV F Protein Nanoparticle Vaccine Manufactured in Insect Cells: a Phase I Dose and Formulation-finding Trial in Adults – Gregory Glenn, Novavax, Inc., Rockville, Maryland, USA Oral Presentation
Immunogenicity and Safety of H1N1 Vaccination in Adults aged 19–40 years Vaccinated with Seasonal Influenza Vaccine 4 months Previously – Sumita Roy-Ghanta, GlaxoSmithKline Biologicals, King of Prussia, Pennsylvania, USA confirmed
12.45 – 13.15
Closing Panel: Cathryn Macrae, Selim Badur, Nancy Cox, Ab
Osterhaus, Arnold Monto, Fred Hayden

Source: http://www.turkpediatri.org.tr/PediatriData/userfiles/file/ISRVI_XIV_Program%2012_15_11.pdf

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