Comprehensive list of publications – Prof.dr. Slappendel
Publications with impact factor:
1.
Spread of radiopaque dye in the thoracic epidural space. R.Slappendel, M.J.M.Gielen, M.A.W.M.
Hasenbos, F.J.M. Heystraten. Anaesthesia 1988;43:939-940.
Continue thoracale epidurale infusie als postoperatieve pijnbestrijding. R.Slappendel, M.A.W.M.
Hasenbos, M.J.M. Gielen, M.N.Eckhaus. NTVG,1989;133:47:2362.
Continuous high thoracic epidural administration of bupivacaine with sufentanil or nicomorphine
for postoperative pain relief after thoracic surgery. Hasenbos M.A.W.M., Eckhaus M.N.,
Slappendel R., M.J.M. Gielen. Regional Anesthesia 1989;14:5:212-218.
Life treatening postoperative stridor. P.W.Allen, H.G.Kho, R.Slappendel. European J.
Asymmetric onset of sympathetic blockade in epidural anesthesia shows no relation to epidural
catheter position. M.J.M. Gielen, R.Slappendel, J.L.Merx. Acta Anesthesiol Scand 1991;35 :81-84.
Radiofrequency lesioning of the stellate ganglion. R.Slappendel, B.J.P.Crul, R.T.M. van Dongen.
General anesthesia for surgical repair of intracranial aneurysm in pregnancy: effects on fetal
heart rate. Buul B.J.A., Nijhuis J.G., Slappendel R., Lerou J.G.C. American Journal of Perinatology
The stellate ganglion in magnetic resonance imaging: a quantification of the anatomic variability.
Slappendel R, Thijssen HO, Crul BJ, Merx JL Anesthesiology 1995 Aug;83(2):424-426.
Intrathecal administration of morphine and bupivacaine in the treatment of severe pain in chronic
pancreatitis. Verheijen R, Slappendel R, Jansen JB, Crul BJ, van Dongen RT Ned Tijdschr Geneeskd
10. The efficacy of radiofrequency lesioning of the cervical spinal dorsal root ganglion in a double
blinded randomized study: no difference between 40 degrees C and 67 degrees C
treatments.Slappendel R, Crul BJ, Braak GJ, Geurts JW, Booij LH, Voerman VF, de Boo T. Pain
11. Intrathecal addition of morphine to bupivacaine is not the cause of postoperative nausea and
vomiting. Weber EWG, Slappendel R, Gielen MJM, Dirksen R. Reg Anesth Pain Med 1998
12. The intensity of preoperative pain is directly correlated with the amount of morphine needed for
postoperative analgesia. R.Slappendel, E.W.G. Weber, M.L.T. Bugter, R. Dirksen. Anesth Analg
13. Intrathecal addition of morphine to bupivacaine. Letter to the editor. Weber EWG, Slappendel R,
Gielen MJM, Dirksen R. Reg Anesth Pain Med 1999;24(1):94-95
14. Optimization of the dose of intrathecal morphine in total hip surgery: a dose finding study. R.
Slappendel, E.W.G. Weber, R. Dirksen, M.J.M. Gielen, J. van Limbeek. Anesth Analg 1999
15. Lumbar sympathectomy in critical limb ischaemia: surgical, chemical or not at all? FAC Holiday,
WB Barendregt, R.Slappendel, BJP Crul, FGM Buskens, JA van der Vliet. Cardiovascular Surgery
16. Noninvasive measurement of bladder volume as an indication for bladdercatheterization after
orthopedic surgery and its effect on urinary tract infections. R. Slappendel, E.W.G. Weber.
European Journal of Anaesthesiology 1999, 16, 503-506.
17. Aspects of intrathecal morphine for postoperative pain relief after major orthopedic surgery. R.
Slappendel. Thesis, academisch ziekenhuis Utrecht. Promotor Prof. Dr. J.T.A. Knape. 13 June
18. Substance P. D.G. Snijdelaar, R.Dirksen, R.Slappendel, B.J.P. Crul. Eur.J.Pain 2000,4:121-135.
19. Psychological predictors of the effectiveness of radiofrequency lesioning of the cervical spinal
dorsal ganglion (RF-DRG). H. Samwel, R. Slappendel, B.J.P. Crul, V.F. Voerman. Eur J Pain
20. Itching after intrathecal morphine. Incidence and treatment. R.Slappendel, E.W.G. Weber, B.
Benraad, J. van Limbeek , R. Dirksen. European J. Anaesthesiology 2000; 17: 616-621.
21. The incidence of transient neurological symptoms after spinal anaesthesia with lidocaine
compared to prilocaine. De Weert K, Traksel M, Gielen M, Slappendel R, Weber E, Dirksen R.
22. One drop of morphine added to local anesthetics by means of a 23-gauge injection needle can
relieve postoperative pain under spinal anesthesia. Toyoyama H, Mizutani K, Toyoda Y,
Slappendel R, Benraad B, Dirksen R, Weber EW, Gielen MJ, van Limbeek J . Anesth Analg 2000
23. Does ibuprofen increase perioperative blood loss during hip arthroplasty? R.Slappendel, E.W.G.
Weber, B. Benraad, R. Dirksen, M.L.T. Bugter. European Journal of Anaesthesiology 2002; 19:
24. Use of Recombinant Factor VIIa (Novoseven) to Reduce Postoperative bleeding after Total Hip
Arthroplasty in a patient with severe Cirrhosis and Thrombocytopenia. R. Slappendel, F.C.Huvers,
B.Benraad, I.Novàkova, G.G. van Hellemondt, Anesthesiology 2002; 96: 1525-7.
25. Prior ibuprofen exposure does not augment opioid drug potency or modify opioid requirements for
pain inhibition in total hip surgery. L'exposition prealable a l'ibuprofene n'augmente pas l'effet des
opiaces ou ne modifie pas les besoins d'opiaces pour l'analgesie de l'arthroplastie totale de la
hanche. Bugter ML, Dirksen R, Jhamandas K, Slappendel R, Weber EW, Milne B. Can J Anaesth
26. Transcranial electrical motor-evoked potential monitoring during surgery for spinal deformity: a
study of 145 patients. Langeloo DD, Lelivelt A, Louis Journee H, Slappendel R, De Kleuver M.
27. Use of recombinant factor VIIa (NovoSeven) to reduce postoperative bleeding after total hip
arthroplasty in a patient with cirrhosis and thrombocytopenia. Slappendel R, Huvers FC, Benraad
B, Novakova I, van Hellemondt GG. Anesthesiology 2003 Apr; 98(4):1025-7.
28. Don’t make an easy block more difficult! Jack N, Slappendel R, Gielen M. Letter to the editor.
Regional Anesthesia and Pain Medicine October 2003.
29. An algorithm to reduce allogenic red blood cell transfusions for major orthopedic surgery. R.
Slappendel, R. Dirksen, EWG Weber, DB van der Schaaf. Acta Orthop Scand 2003; 74 : (5): 569-
30. COX 2 selectivity of non-steroidal anti-inflammatory drugs and perioperative blood loss in hip
surgery. A randomized comparison of indomethacin and meloxicam. EWG Weber, R.Slappendel,
ME Durieux, R. Dirksen, H. van der Heide, M.Spruit. Eur. J. Anaesthesiology 2003; 20: 963-966.
31. Effects of epoetine alfa on blood transfusions and postoperative recovery in orthopaedic surgery-
The European epoetin alfa Surgery Trial (EEST). E.W.G. Weber, R.Slappendel, Y Hemon, S.
Mahler, T. Dalen, E. Rouwet, J. van Os, A. Vosmaer, P. van der Ark. European Journal of
32. Blood management after bilateral total knee arthroplasties. Slappendel R, Dirksen R. Clin Orthop.
33. Reduction of blood loss using high-dose aprotinin in major orthopaedic surgery. Slappendel R,
Dirksen R, Van Hellemondt GG. J Bone Joint Surg Br. 2004; 86(4):620; 620-1.
34. Profylaxis for heterotopic ossification after primary total hip arthroplasty. A Cohort study between
indomethacin and meloxicam. Huub J.L. van der Heide, Maarten Spruit, Rob Slappendel, Niels
Klooster, Jacques van Limbeek. Acta Ortop. Belg, 2004, 70, 240-246.
35. Clinical efficacy of postoperative autologous transfusion of filtered shed blood in hip and knee
arthroplasty. Strumper D, Weber EW, Gielen-Wijffels S, Van Drumpt R, Bulstra S, Slappendel R,
Durieux ME, Marcus MA. Transfusion. 2004 Nov;44(11):1567-71.
36. Successful defibrillation immediately after the intravascular injection of ropivacaine: [Defibrillation
reussie immediatement apres l'injection intravasculaire de ropivacaine]. Gielen M, Slappendel R,
Jack N. Can J Anaesth. 2005 May;52(5):490-2.
37. Perioperative blood transfusions and delayed wound healing after hip replacement surgery:
effects on duration of hospitalization. Weber EW, Slappendel R, Prins MH, van der Schaaf DB,
Durieux ME, Strumper D. Anesth Analg. 2005 May; 100 (5):1416-21.
38. Effects of epoetin alfa on blood transfusions and postoperative recovery in orthopaedic surgery:
the European Epoetin Alfa Surgery Trial (EEST). Eur J Anaesthesiol. 2005 Apr;22(4):249-57.
Weber EW, Slappendel R, Hemon Y, Mahler S, Dalen T, Rouwet E, van Os J, Vosmaer A, van der
39. Risks associated with blood transfusion after total knee arthroplasty. Slappendel R. J Arthroplasty.
40. Successful defibrillation immediately after the intravascular injection of ropivacaine. Gielen M,
Slappendel R, Jack N. Can J Anaesth. 2005 May;52(5):490-2.
41. Validation of the PAC-SYM questionnaire for opioid-induced constipation in patients with chronic low
back pain. Slappendel R, Simpson K, Dubois D, Keininger DL. Eur J Pain. 2005 May 20.
42. Effects of epoetin alfa on blood transfusions and postoperative recovery in orthopaedic surgery: the
European Epoetin Alfa Surgery Trial (EEST)
Eur J Anaesthesiol. 2005 Apr;22(4):249-57.
43. Treatment of postoperative bleeding after fondaparinux with rFVIIa and tranexamic acid.
44. Transdermal fentanyl versus sustained release oral morphine in strong-opioid naive patients with
chronic low back pain.2005 Nov 15;30(22):2484-
45. Patients with and without rheumatoid arthritis benefit equally from preoperatiev epoetine-alpha
treatment. R. Slappendel et al. Acta Orthop 2006 aug; 77 (4): 677-83.
46. Validation of the PAC-SYM questionnaire for opioid-induced constipation in patients with chronic low
back pain. R.Slappendel et al Eur J Pain. 2006 Apr;10(3):209-17.
47. Predicting long-term response to strong opioids in patients with low back pain: findings from a
randomised, controlled trial of transdermal fentanyl and morphine. Eija Kalso, Karen H Simpson,
Robert Slappendel, Joachim Dejonckheere and Ute Richarz. BMC Medicine 2007 Dec 21;5:39.
N Engl J Med. 2008 Jun 26;358(26):2776-86.
Engl J Med. 2008 Jun 26;358(26):2765-75.
50. Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical
patient: NATA guidelines. British Journal of Anaesthesia 106 (1): 13–22 (2011). L. T. Goodnough, A.
Maniatis, P. Earnshaw, G. Benoni, P. Beris, E. Bisbe, D. A. Fergusson, H. Gombotz, O. Habler, T. G.
Monk, Y. Ozier, R. Slappendel and M. Szpalski.
51. Autologous platelet gel in total knee arthroplasty: a prospective randomized study.
Sports Traumatology, Arthroscopy9(1): 115-21.
52. Laboratory characteristics and clinical utility of post-operative cell salvage: washed or unwashed blood
54. Postoperative autologous blood transfusion drain or no drain in primary total hip arthroplasty? A
randomized controlled trial." W.G. Horstmann, Bart M. Kuipers, Robert Slappendel, Rene Castelein,
Boudewijn J. Kollen, Cees C.P.M. Verheyen. Accepted for publication in International Orthopaedics.
55. Dalende ziekenhuissterfte gaat mogelijkheden van orgaan- en weefseldonatie beïnvloeden. Edwin P
Vorstius Kruijff, Rob Slappendel, Maartje LG de Vos, Nardo JM van der Meer. Geaccepteerd NTVG.
Publications without impact factor
1. Longventilatiemetingen in een beroepsbevolking. W.L.M. Rijnders, R.Slappendel, D.Vroege.
Tijdschrift voor sociale geneeskunde 1982;60:18:504-507.
2. Adenotonsillectomie bij een patientje met het syndroom van Holt-Oram. R.Slappendel,
J.J.Canning. Nederlands tijdschrift voor anesthesiologie 1988;1:2:27-30.
3. Hartritmestoornissen tijdens adenotomie en adenotonsillectomie. Een vergelijking tussen trileen
en halothaan. R.Slappendel, J.M.J. Rutten. Nederlands tijdschrift voor anesthesiologie
4. Gaslekkage bij een verdamper als oorzaak van levensbedreigende hypoventilatie. R.Slappendel,
W.Thewisse, J.T.A. Knape. Nederlands tijdschrift voor anesthesiologie 1990;3:2:84-89.
5. Eerste ervaringen met het larynxmasker in Nederland. J.B.M. Harbers, F.T.M. ten Have,
J.E.Moll, R.Slappendel. Nederlands tijdschrift voor anesthesiologie 1991;4:68-73.
6. Pleurale toediening van bupivacaine bij chronische benigne pijnpatienten in de thuissituatie.
R.Slappendel, H.J.G.Jessen, B.J.P.Crul, R.T.M. van Dongen. Nederlands tijdschrift voor
7. Radiofrequency lesioning of the stellate ganglion. R.Slappendel, B.J.P.Crul, R.T.M. van Dongen.
8. Intrapleural analgesia: a new scope for treatment of chronic benign pain at home. R.Slappendel,
9. Intrapleurale blokkade met lokale anaesthetica. R.Slappendel, B.J.P.Crul, H.J.G.Jessen.
10. Radiofrequente laesie technieken in de cervicale regio. Een inventarisatie van enkele
onderzoeksmogelijkheden. B.J.P.Crul, R.Slappendel, V.F.Voerman. Nederlands tijdschrift voor
11. Gastrointestinal side effects diminishes after switch over from morphine to trandermal fentanyl.
R.Slappendel, S.J. Lako, B.J.P.Crul. Annals of Oncology 1994; 5:200.
12. Pain management in chronic pancreatitis. R.Verheijen, R.Slappendel, J.B.M.J.Jansen, B.J.P.Crul.
13. MR guided localization of the stellate ganglion. H.M.Cornelisse, R.Slappendel, H.O.M.Thijssen,
B.J.P.Crul. Regional Anesthesia, 1995, 20, 2S, 142.
14. Elevated sensory thresholds in patients suffering from chronic cervicobrachialgia. V.F.Voerman,
J. van Egmond, B.J.P. Crul, R. Slappendel. The Pain Clinic, 1996, vol 9, No 4: 425-435.
15. Treatment of side effects after intrathecal morphine in Major orthopedic surgery. R. Slappendel,
E.W.G. Weber. The international monitor 1997; vol9: no3, 144.
16. TENS bij patiënten met ernstige chronische cervicobrachialgie. R. Slappendel, Staal H,
Oosterhof J, van Egmond J, Crul B.J.P. NVGPT; 1997:15, 7-10.
17. Bijeffecten van intrathecaal morfine. R.Slappendel, E.W.G.Weber, R.Dirksen, M.J.M. Gielen.
Nederlands tijdschrift voor Anesthesiologie. 1997, 10, 1-6.
18. Noninvasive measurement of bladder volume as an indication for bladdercatheterization after
orthopedic surgery and its effect on urinary tract infections. R. Slappendel, E.W.G. Weber.
European Journal of Anaesthesiology 1999, 16, 503-506.
19. Blaasvolumemeting op verkoeverkamer verplicht na kleinere (orthopedische) ingrepen? R.
Slappendel, T.A. Brouwer, M.L.T. Bugter, R. Dirksen, E.W.G. Weber. Nederlands tijdschrift voor
20. Aanpassing en invoering van het CBO transfusieprotocol in de dagelijkse praktijk van de Sint
Maartenskliniek leverde een halvering van het packed cell verbruik op. R. Slappendel, E.W.G.
Weber , D. B. van der Schaaf , J. D. Oosting. kwaliteitsjournaal August 1999.
21. Prevention of urinary tract complications starts at the recovery room by non-invasive bladder
volume measurement. E.W.G. Weber, R. Slappendel, T. Brouwer, R. Dirksen, M.L.T. Bugter.
22. Radiofrequente laesies van het ganglion stellatum bij chronische pijnsyndromen: een
retrospectieve analyse van 86 patiënten. Letter to the editor. R.Slappendel, B.J.P. Crul, R.T.M.
van Dongen, R. Dirksen. NTTP, 19, no 4, 1999: 91.
23. Halvering van de toediening van packed cells bij geprotocol eerde indicatiestelling. E.W.G.
Weber , R. Slappendel , D. B. van der Schaaf , J. D. Oosting . Nederlands tijdschrift voor
24. Side effects of Cox-selective NSAID’s after orthopedic surgery. R. Slappendel, R. Dirksen, E.W.G
Weber. M.L.T.Bugter. Annals of the Rheumatic diseases July 2000, vol 59: page 61.
25. Fantoomsensaties tijdens plexus brachialis anesthesie. R. Dirksen, S te Giffel, R.Slappendel,
P.A.T.M Eling, M.L.T. Bugter, L.M.G. Geeraedts, E.W.G. Weber. Nederlands tijdschrift voor
26. Cox-2 selectiviteit van de niet steroide anti-inflammatoire medicamenten (NSAID’s) en het
peroperatief bloedverlies. R.Slappendel, R.Dirksen, M.A.P. Kooijman, D.B. van der Schaaf,
G.A.A Bloemen, E.W.G. Weber, M.L.T. Bugter. Nederlands tijdschrift voor Anesthesiologie 2000;
27. Preoperative VAS scores and phantom limb sensations during brachial plexus anesthesia.
R.Dirksen, P.Eling, M.Bugter, S te Giffel, E.Weber, R.Slappendel. Neuroscience 2000;abstract:
28. Bladderscan: reductie van catheters en urineweginfecties. R.Slappendel, E.W.G. Weber. NTVa
29. One drop of morphine added to local anesthetics by means of a 23-gauge injection needle can
relieve postoperative pain under spinal anesthesia. Toyoyama H, Mizutani K, Toyoda Y,
Slappendel R, Benraad B, Dirksen R, Weber EW, Gielen MJ, van Limbeek J . Anesth Analg 2000
30. Preoperative VAS scores and phantom limb sensations during brachial plexus anesthesia,
R.Dirksen, P. Eling, M. Bugter, S. te Giffel, E. Weber, R. Slappendel. Ned. Tijdschrift voor
31. Uitgifte van packed cells gekoppeld aan het pretransfusie hemoglobinegehalte halveert het
packed cell verbruik, R. Slappendel, E. Weber, J.D. Oosting. Nederlands tijdschrift voor
32. Antidepressants: how do they influence nociception? R. Dirksen, R. Slappendel.
Neurogastroenterology & Motility, 12 (4), 2000, 371.
33. Gebruik van bloed kan flink omlaag. R.Slappendel. Dagblad Trouw 29-9-2000.
34. Forse besparing op donorbloed mogelijk. R.Slappendel. Dagblad Gelderlander 29-9-2000.
35. Preoperative VAS scores and phantom limb sensations during brachial plexus anesthesia,
R.Dirksen, P. Eling, M. Bugter, S. te Giffel, E. Weber, R. Slappendel. Neuroscience, Soc.
36. Aspects of intrathecal morphine for postoperative pain relief after major orthopedic surgery. R.
Slappendel. Nederlands tijdschrift voor anesthesiologie 2000; 13:29.
37. Blaasvolume meting op de verkoeverkamer: verplicht na kleine orthopedische ingrepen?
R.Slappendel, M.L.T. Bugter, R. Dirksen, E.W.G. Weber. Kortom (NVDK) 2000; 4: 7.
38. Het voorkomen van homologe bloedtransfusies met de cell saver. H.E. Polak, A.G.H. Rutten,
R.Slappendel, M. de Kleuver. NTVA 2001; 18:21-26.
39. Bloedmanagement of transfusierichtlijn. F. Luijcks, R. van den Hurk, I Ehlebracht, R.
40. Bloedeloze patiënt krijgt toch geen transfusie. Interview R. Slappendel, R. Dirksen. Volkskrant
41. Dose Ranging Investigation of Oral Immediate-Release Hydromorphone (Dilaudid® IR) in Acute
Post-Operative Pain. R.Slappendel, J.M. Debue, J.J. Helouis, R. Verheijen, C. Durnin, D.
Rowbotham. Minerva anesthesiology. 2001: : pages.
42. A Comparison of Oral Immediate-Release Hydromorphone (Dilaudid® IR) and morphine in
Acute Post-Operative Pain. R.Slappendel, J.J. Helouis, R. Verheijen, M.A. Goulder, D.
Rowbotham. Minerva anesthesiology. 2001: : pages.
43. Anesthesiologen vinden manier van besparing. Minder bloed bij operaties. R.Slappendel, E.W.G.
Weber, R.Dirksen, M.L.T. Bugter, N.T.M. Jack. Algemeen Dagblad 31 August 2001.
44. Zuinig met bloed. R.Slappendel, R.Dirksen, E.W.G. Weber, M.L.T. Bugter, N.T.M Jack. Medisch
Contact, 31 August 2001: 56, nr 35: blz 1250 –1252.
45. Medisch contact 56 jaargang 9 November 2001, Slipcursus, R.Dirksen, R.Slappendel.
46. Resultats dúne aproche de limitation des pertes sanguines dans la pratique clinique.
R.Slappendel. Communications scientifiques MAPAR 2002. pp 187-190. ISBN 2-905356-26-X.
47. Vermindert scopolamine postoperatieve misselijkheid en braken na spinaal anesthesie? Een
pilotstudie bij 70 patiënten. R.Slappendel, R. Dirksen. OK-compleet 2002; 1:3-6.
48. Ter voorkoming van homologe bloedtransfusies. Het preoperatief gebruik van erytropoietine en
ijzer. M. de Metz, R. Slappendel. Analyse 2002; 57:
49. Plexus brachialis blokkade, complicaties van de dorsale benadering. N.T.M. Jack, M.L.T. Bugter,
R. Dirksen, R. Slappendel, E.W.G. Weber. NTVA 2002, vol 15, blz 42-44.
50. Ruim baan voor eigen bloed. Autologe predonatie kan veel beter. R.Slappendel, R. Dirksen.
51. Transfusie eigen bloed veel beter. Strenge regels verhinderen vaak toepassing. R. Slappendel,
R. Dirksen. Telegraaf , 2 November 2002: pagina 6.
52. Blood transfusion and postoperative recovery,– The European Eprex Surgery Trial. R.Slappendel
Transfusion alternatives in Medicine vol 5, number 1, supplement April 2003: 23-24.
53. Prior ibuprofen exposure does not augment opioid drug potency or modify opioid requirements
for pain inhibition in total hip surgery. L'exposition prealable a l'ibuprofene n'augmente pas
l'effet des opiaces ou ne modifie pas les besoins d'opiaces pour l'analgesie de l'arthroplastie
totale de la hanche. Bugter ML, Dirksen R, Jhamandas K, Slappendel R, Weber EW, Milne B. Can
54. Angst voor operatie: Autorijden is riskanter! R. Slappendel. Wervelingen. Vereniging van
scoliose patienten. Zomer 2003: pagina 6-7.
55. No unnecessary autologous predonation of blood. R. Slappendel, R. Dirksen. Clinical
56. Autologe predonatie van bloed in eigen beheer? R.Slappendel, R.Dirksen. Ned Tijdschr Klin
57. Pijnstillers van de poliklinische apotheek. Doelmatige pijnbestrijding na operaties in
dagbehandeling. M. Deurvorst, R. Slappendel, B. Benraad, R. Dirksen. Medisch Contact 2003.
58. Een NEN-EN-ISO 9001: 2000 gecertificeerd bloedmanagement proces. R. Dirksen, R.
Slappendel, D.B. van der Schaaf , M. Lemans, A.A. van Dijk. Medisch Contact 2004.
59. Blood transfusions and postoperative recovery in orthopedic surgery. The European Eprex
Surgery trial. Robert Slappendel, Eric Weber. Transfusion alternatives in transfusion medicine.
60. The Pharmacoeconomics of alternatives to allogeinic blood transfusion. Marinus van Hulst,
Robert Slappendel, Maarten J. Postma. Transfusion alternatives in transfusion medicine. 2004:
61. Blood management after bilateral total knee arthroplasties. Slappendel R, Dirksen R. Clin
62. Reduction of blood loss using high-dose aprotinin in major orthopaedic surgery. Slappendel R,
Dirksen R, Van Hellemondt GG. J Bone Joint Surg Br. 2004; 86(4):620; 620-1.
63. Ruimtelijke fantoomperceptie tijdens spinale anesthesie. Knippenberg ML, Dirksen R, Eling
PATM, Slappendel R. Nederlands tijdschrift voor Pijn en pijnbestrijding. 2004, 23 (18): 6-9.
64. Blood policy and outcome in orthopedics in the Netherlands. R. Slappendel, H. Naber, J. van Os,
Transfusion alternatives in transfusion medicine. April 2005: vol 7; 5: 87.
65. Uw eigen autologe bloedbank. R. Slappendel; R. Dirksen. ISBN 90-8092 18-4-X.
66. NEN-EN-ISO 9001-2000 certified blood management Sint Maartenskliniek. November 2005. R.
Slappendel; R. Dirksen. ISBN 90-8092 18-3-1
67. Opereren zonder verkoever. R.Slappendel, L. Vonhögen, N.Jack, C.Gort, R.Dirksen. Medisch Contact
68. Bloedbeleid in de orthopedie in Nederland – resultaten van een survey. R.Slappendel H.R. Naber, J.J.
van Os, P. Bergmans. Nederlands tijdschrift voor orthopedie. 2005; vol 12: 212-216.
69. Patients with and without rheumatoid arthritis benefit equally from preoperatiev epoetine-alpha
treatment. R. Slappendel et al. Acta Orthop 2006 aug; 77 (4): 677-83.
70. Neuromodulatie SCS voor FBSS NEN-ISO 9001:200 gecertificeerd. January 2007 R. Slappendel; R.
71. Het posttrombotisch syndroom na heup- en knievervangende operaties – de invloed van nadroparine
en fondaparinux. Nederlands tijdschrift voor orthopedie 2007; vol 14: 11-14.
72. Het posttrombotisch syndroom na heup- en knievervangende operaties – de invloed van nadroparine
en fondaparinux. Nederlands tijdschrift voor orthopedie 2007; vol 14: 11-14.
73. Wound drainage wit or without blood salvage? An open, prospective, randomized and single center
comparison of blood loss, postoperartive hemoglobine levels and allogeneic blood transfusions after
major hip surgery. R. Slappendel, W. Horstmann, R. Dirksen, G.G. van Hellemondt. Transfusion
alternatives in transfusion medicine. 2009; 10: 174-181.
74. Blood Transfusions and Postoperative Recovery – The European Eprex Surgery Tria
75. The Pharmacoeconomics of Alternatives to Allogeneic Blood Transfusion.
76. Minder transfusies veel gezonder. Zorg laat enorme bedragen liggen door ontbreken van financiële
prikkels. Financieel Dagblad 6-4-2009. Rob Slappendel, Ris Dirksen.
77. Safety of retransfusion of filtered shed blood in 1819 patients after total hip or knee surgery.
Transfusion Alternatives in Transfusion medicine 2010, vol 11, issue 2: 57-64.
78. Autologous platelet gel in total knee arthroplasty: a prospective randomized study.
Sports Traumatology, Arthroscopy9(1): 115-21.
79. Individuelle Hämotherapie am Beispiel der Niederlanden – Methoden, Qualitätskontrolle, Erfolg und
Erlös. Anästh Intensivmed 2011;52:42-47. R. Slappendel · T. Frietsch.
80. Grotere sterftekans bij preoperatieve anemie. Effectieve behandeling voorkomt vermijdbare doden.
Medisch Contact 2011; 66 nr 7: 392-393. R.Slappendel, R. Dirksen.
81. Bloedlevering ruim €60 miljoen te duur. Met dezelfde kwaliteitseisen kost bloed in België en
Duitsland ruim de helft minder. Financieel dagblad, 12 April 2011. R. Slappendel, R. Dirksen.
82. Local Infiltration Analgesia (LIA) and Postoperative Blood Salvage can be safely combined in major
orthopedic surgery. Abstract ESRA congress September 2011.Postoperative Pain Management J.R.
83. Valpreventie zonder onrustband . Medisch Contact September 23, 2011.
Presentations on international professional meetings:
Dedicated non invasive bladder volume measurement halves the need for consumables and quarters
urinary tract infections in orthopedic patients, ECA congress, 2 June 1998, Frankfurt, Germany.
The use of the BladderScan in an anesthesiology practise. ESRA Congress, 30 September 1999,
The influence of COX-selective NSAID’s on peroperative blood loss during triple osteotomy of the
pelvis. Annual meeting of the BSAR. 26 November 1999, Gent, Belgium.
Dose Ranging Investigation of Oral Immediate-Release Hydromorphone (Dilaudid® IR) in Acute
Post-Operative Pain. 11th European Congress of Anaesthesiology (CENSA), 7 June 2001, Florence,
An investigation of dilaudid (hydromorphone HCl) in the treatment of acute post-operative pain. R.
Slappendel, J-M. Debue, J-J- Heloui, R. Verheijen, C. Durnin, D. Robotham. European Federation of
IASP Chapters, 26 – 29 September 2000, Nice, France.
Preoperative and postoperative volume analysis. Indications for catheterisation. 9 April 2001. ESA
A Comparison of Oral Immediate-Release Hydromorphone (Dilaudid® IR) and morphinee in Acute
Post-Operative Pain 11th European Congress of Anaesthesiology (CENSA), 7 June 2001, Florence,
Clinical practise to reduce homologous blood transfusions. Your own Blood Congres: Risks and
alternatives of homologous blood transfusion. 28 September 2001, Gothenburg, Sweden.
Questions pour des champions en anesthésie: Effects of blood management in clinical practice,
MAPAR congres, 31 May 2002, Paris, France.
10. Blood transfusion and postoperative recovery – the effect of epoetin alfa in major
orthopaedic surgery. NATA congres, 14 April 2003, Londen, United Kingdom.
11. Preoperative treatment with erytropoietine to reduce blood transfusions in orthopaedic surgery.
The European Eprex surgery trial. Presentation Swedisch Society of Orthopedia, 15 May 2003,
12. Your own blood is good enough. ISO certification perioperative blood management. Finish
Anesthesia Society. 19 November 2003, Helsinki, Finland.
13. Clinical effects of blood management, Irish Blood Bank, 17 April 2004, Dublin, Ireland. 14. Your own blood is good enough. Symposium Your own blood is good enough, 10-7-2004, 15. Blood management in clinical practise. 21-6-2004, Mulgrave hospital, Belfast, Ireland. 16. Use of epoetin alfa in orthopaedic surgery – reducing length of hospital stay? – A model from
the Netherlands, Trent Transfusion Alternatives Symposium Catalis Conference Centre,
17. Validation of PAC-SYM, a 12-item, Patient-reported questionnaire, for opioid induced
constipation in patients with chronic low back pain. 3rd World Congress World Institute of
Pain, 24 September 2004, Barcelona, Spain.
18. High vacuum versus low vacuum drainage in orthopaedic surgery. . Sympsosium actualities
and implementation of blood management in orthopedic surgery. 7 April 2005, Malaga
19. Your own blood is good enough. ISO certification perioperative blood management. .
Satelliet symposium 17 April 2005, NATA congres, Prague, Czech Republic.
20. Advantages of having a bloodmanagement process NEN-EN-ISO 9001: 2000 certified.
Institute of bloodless medicine and surgery, Englewood Hospital, 12 January 2005,
21. Preoperative Early Intervention Strategies: Preparing the Patient for Surgery, NATA 22. Postoperative cell saving, “Blutdepotleterskurs”, (Austrian Anesthesia Society), 25 May 23. NATA expert meeting, Blood conservation in Orthopedic surgery. Developing a blood
conservation program in a center of excellence. A blood management algorithm: NEN-EN-
ISO 9001:2000 certified, 9 March 2007, Barcelona, Spain.
24. “Optimized Blood Management in Clinical Practice". Results of a NEN-EN ISO 9001:2000
certificated strategy. NATA expert meeting 8 November 2007, Amsterdam.
25. “Management of preoperative anemia in a blood conservation algorithm". NATA expert 26. “The value of active blood management for over 50.000 orthopedic patients". ASTRA Tech
symposium, 15 November 2007, Lisbon, Portugal.
27. “Safety of retransfusion of filtered shed blood in 1830 patients undergoing total hip or total
knee arthroplasty implantation". ASTRA Tech symposium, 16 November 2007, Lisbon,
28. “Optimized Blood Management and the role of peri-operative epoetin alfa therapy".
Results of a NEN-EN ISO 9001:2000 certificated strategy. 8th postgraduate course “Blood
therapy” 23 November 2007, Portoroz, Slovenia.
29. “Optimized Blood Management and the role of peri-operative epoetin alfa therapy". Results
of a NEN-EN ISO 9001:2000 certificated strategy. GEAS meeting, 10th January 2008,
30. Do we need blood management? WMS meeting, The Royal College of Anaesthetists, 17 31. “Optimized Blood Management and the role of peri-operative epoetin alfa therapy". Results
of a NEN-EN ISO 9001:2000 certificated strategy. 29 April 2008, Murray, Perth, Scotland.
32. “Management of Perioperative Anemia”, 17 September 2008. V Baltic Congress “Transfusion
Practice & Transfusion Alternatives”, Riga, Letland.
33. “Advantages of having a blood management process NEN-EN-ISO 9001-2000 certified”, 19
September 2008. V Baltic Congress “Transfusion Practice & Transfusion Alternatives”, Riga,
34. “Optimized blood management in orthopaedic surgery” Slovenia anaesthesiology society, 16 35. Blood transfusion management – orthopaedic surgery. Symposium Anaesthesia for
orthopedic surgery, The Association of Anaesthesists of Great Britain and Ireland. 22 October
36. “Blood management in clinical practise, a 2009 update”. 15 April 2009, Pre NATA 37. Bloodmanagement in orthopedic surgery in the Netherlands. Hauptstadtkongress der DGAI
fur anasthesiologie und Intensiv therapie. 17 September 2009, Berlin, Germany.
38. Anaesthesia for Orthopaeadic surgery, Association of Anaesthesia of Great Brittain and 39. Advantages of certified blood management in the last 10 years. Your own blood symposium 40. Können wir uns Anämiemanagement leisten? Hauptstadtkongress der DGAI für
Anästhesiologie und Intensivtherapie. 13 September 2011, Berlin, Germany.
41. Postoperatives Cell Saving: gewaschen oder ungewaschen? Abbsat Anästhesietage, 11 42. Is there a rationale for the use of autologous whole blood? Your own blood symposium, 27
In the same period over 135 presentations were given in national and international hospitals.
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