Journal of Synthetic Organic SYNTHESIS Chemistry Special Issue Developing Novel Organocatalyzed Aldol Reactions for the Enantioselective ew Synthesis of Biologically Active Molecules Revi e 1831 A Novel Catalyst-Free Tandem Reaction for the Synthesis of 5-Hydroxy-1,5- cl dihydro-2H-pyrrol-2-ones in Water Medium ti re Ar eatu F Synthesis of 4-Hydroxy-4H-chromenes by Reaction of Salicylic Aldehydes with Alkynals Catalyzed by Silyl Prolinol Ethers pers Pa Table of Contents Organocatalytic Conjugate Additions of Acetylacetone to 3-Ylideneox- s indoles: A Direct Access to Highly Enantioenriched Oxindole Derivatives Paper Origins of Enantioselectivity in Proline-Catalyzed Friedländer Conden- sations of 4-Substituted Cyclohexanones lowest-energy transition state Formation of Functionalized Cyclopentenes via Catalytic Asymmetric [3+2] Cycloaddition of Acrylamides with an Allenoate Promoted by Dipeptide- Derived Phosphines Isothiourea-Catalyzed Asymmetric O- to C-Carboxyl Transfer of Furanyl Carbonates
C. D. CampbellA. M. Z. SlawinA. D. Smith*
Table of Contents s 1880 Enantioselective Organocatalytic Aryloxylation of b-Keto Esters Paper Organocatalytic Domino Double Michael Reaction of Ethyl (E)-7-Oxohept-2- enoate and a,b-Unsaturated Aldehydes: Efficient Asymmetric Synthesis of Cyclohexanes with Four Contiguous Stereocenters Synthesis of Spiro Bis-Indanes via Domino Stetter–Aldol–Michael and Stetter–Aldol–Aldol Reactions: Scope and Limitations Organocatalytic Asymmetric Synthesis of Functionalized 4H-Chromenes via a One-Pot Domino Michael-Hemiacetalization and Dehydration Sequence Table of Contents Highly Efficient and Modularly Tuned Bicyclic Organocatalyst for the s Enantioselective Michael Addition of Aldehydes to Nitroalkenes Paper Amino Acid Catalysed Aldol Reactions in Cyclic Carbonate Solvents
catalyst (10 mol%)wet cyclic carbonate solvent
5 ketones, 6 aldehydes, 2 solvents and 2 catalysts
yield up to 98%diastereoselectivity up to 100% in favour of the
anti-diastereomeree of anti-diastereomer up to 95%
Chiral Bis-pyridinium Salts as Novel Stereoselective Catalysts for the Metal-Free Diels–Alder Cycloaddition of a,b-Unsaturated Aldehydes catalyst Efficient Organocatalytic Dual Activation Strategy for Preparing the Versatile Synthons (2E)-1-(Het)Aryl/styryl-3-(dimethylamino)prop-2-en-1- ones and a-(E)-[(Dimethylamino)methylene]cycloalkanones Table of Contents s 1936 Enantioselective Route to b-Silyl-d-keto Esters by Organocatalyzed Regioselective Michael Addition of Methyl Ketones to a (Silylmethylene)malonate and Their Use in Natural Product Synthesis Paper Lithium Aldol Reactions of a-Chloroaldehydes Provide Versatile Building Blocks for Natural Product Synthesis Organocatalytic Enantioselective Approach to the Synthesis of Verbalactone and (R)-Massoialactone A Cooperative Catalysis Approach to the Morita–Baylis–Hillman Reaction of Aryl Vinyl Ketones cooperative catalysis: Table of Contents Highly Enantioselective Michael Addition of Ketones and an Aldehyde to s Nitroalkenes Catalyzed by a Binaphthyl Sulfonimide in Water Paper Kinetic Resolution of Secondary Alcohols by NHC-Catalyzed Oxidative Esterification Diastereoselective Synthesis of Bicyclo[2.2.2]octan-2-one Derivatives through an Unexpected Organocatalytic Tandem Michael–Michael Reaction Towards a Catalytic Asymmetric Version of the [3+2] Cycloaddition between Hydrazones and Cyclopentadiene Table of Contents s 1993 A Novel Recyclable Organocatalytic System for the Highly Asymmetric Michael Addition of Aldehydes to Nitroolefins in Water Paper
catalyst 1 (3 mol%) 4a (21 mol%), H2O, r.t. N-Heterocyclic Carbene Catalyzed Cyclization Cascades of 3-Halopropenals and Arylnitroso Compounds to 2,3-Disubstituted Isoxazol-5(2H)-ones Phosphine-Catalyzed [3+2] Cyclizations: Applications to the Enantio- selective Synthesis of Cyclopentene-Fused Chromanones and Dihydro- quinolinones Table of Contents Author Index
Sunflower Electric Power Corporation August, 2005 Tom Zerfas at x357 or a member of the Committee Also in this issue: Cost Cap Update An Ounce of Prevention. Determining PPO Heard It Through The Savvier Car Buyers Than Providers Grapevine Healthcare Consumers? A recent study performed by • Wholesale prices for What can we learn from Great-We
Journal of Applied Pharmaceutical Science 01 (08); 2011: 235-238 Over prescribing and resistance to chloroquine Gandhi AM, Patel PP, Desai CK, Desai MK and Dikshit RK ABSTRACT Malaria is a major health concern in the developing world including India. Overdiagnosis and overprescribing of malaria may lead to increase morbidity, mortality and o antimalarial drugs and hence increase t
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