Cross reaction guide

Individual Reaction Key
Methadone(MTD)
Phencyclidine(PCP)
Amphetamines(AMP)
Tricyclic Antidepressants(TCA)
Oxycodone(OXY)
Barbiturates(BAR)
Methamphetamines(MET)
Benzodiazepines(BZO)
Tramadol(TML)
Opiates(OPI, MOP, MOR)
Marijuana(THC)
Ecstasy(MDMA)
Cotinine(COT)
Cocaine(COC)
Buprenorphine(BUP)
Propoxyphene(PPX)
Non-reactive
Multiple Reaction Key
MET and AMP
OPI and OXY
MDMA and MET
MDMA and AMP
MET and TCA
Generic Name of Compound
Trade Name of Compound
6-Acetylmorphine
Positive: Opiates(OPI, MOP, MOR)
Aceta, Acephen, Apacet, Dapacen, Feverall,
Acetaminophen (aka Paracetamol)
Tylenol, Excedrin (combination), Panadol,
Non-reactive
Acetaminophen with Codeine (aka
Positive: Opiates(OPI, MOP, MOR)
Tylenol 3, Tylenol with Codeine
Paracetamol with Codeine)
Potential reactants: Dihydrocodeine
Acetophenetidin
Phenacetin
Non-reactive
Aspirin, Anadin, Anasin, Bufferin, Caprin,
Acetylsalicyclic Acid
Disprin, Ecotrin, Empirin, Excedrin
Non-reactive
(combination)
Allobarbital
Positive: Barbiturates(BAR)
Alphenol
Positive: Barbiturates(BAR)
Positive: Benzodiazepines(BZO) Potential
Alprazolam
reactants: Oxaprozin (Daypro), Sertraline
Aluminum Chloride Hexahydrate
Drichlor, Anhydrol Forte
Non-reactive
Alu-Cap, Alisone, Gastrocote, Kolanticon,
Aluminum Hydroxide
Non-reactive
Maalox TC, Mucogel, Pyrogastrone, Topal
Alverine Citrate
Spasmonal, Spasmonal Fibre
Non-reactive
Amantadine
Symmetrel
Positive: Amphetamines(AMP)
Aminopyrine
Non-reactive
Elavil, Lentizol, Tryptizol, Triptafen, Triptafen-
Amitriptyline
Positive: Tricyclic Antidepressants(TCA)
Ammonia/Ipeacuanha
Non-reactive
Amobarbital
Amytal, Tuinal
Positive: Barbiturates(BAR)
Amoxicillin/Amoxycillin
Amoxil, Amoram, Augmentin, Heliclear
Non-reactive
Positive: Amphetamines(AMP),
Methamphetamines(MET) Potential
AMP: Adderall, Dexedrine, Benzedrine
Amphetamine / Methamphetamine
reactants: Ephedrine, Pseudoephedrine,
M/AMP:Desoxyn, Didrex, Eldepryl
Phenylpropanolamine, Phentermine,
Phenmetrazine, Ranitidine
Ampicillin
Penbritin, Polycillin, Principen
Non-reactive
Antazoline Sulphate
Otrivine-Anistin
Non-reactive
Aprobarbital
Positive: Barbiturates(BAR)
Bayer Aspirin, Excedrin, ASA, Angettes,
Non-reactive
Asasantin, Caprin
Beta-adlat, Co-tenidone, Kalten, Tenben,
Atenolol
Non-reactive
Tenif, Tenoret50, Tenorectic, Tenormin
Atorvastatin
Non-reactive
Azlocillin
Securopen
Non-reactive
Barbital
Positive: Barbiturates(BAR)
AeroBec, AeroBec Forte, Asmabec, Beclazone,
Beclometasone
Becloforte, Becodisks, Beconase, Becotide,
Non-reactive
Fillair, Nasobec, Qvar, Ventide, Zonivent
Aprinox, Cogaretic, Indertic, Inderex, Neo-
Bendrofluazide
Non-reactive
Naclax, Neo-Naclax-K, Prestim, Tenben
Benzalknonium
Bradosol
Non-reactive
Generic Name of Compound
Trade Name of Compound
Positive: Benzodiazepines(BZO) Potential
Benzodiazepines
Individual Benzodiazepines Listed
reactants: Oxaprozin (Daypro), Sertraline
Benzoylecgonine
Positive: Cocaine(COC)
Benzydamine HCL
Non-reactive
Benzylpenicillin
Crystapen
Non-reactive
Positive: Benzodiazepines(BZO) Potential
Bromazepam
reactants: Oxaprozin (Daypro), Sertraline
Bromopheniramine
Dimetapp, Dimotapp, Dimotane
Non-reactive
Buprenorphine (Suboxone)
Suboxone, Subutex, Temgesic
Positive: Buprenorphine(BUP)
Bupropion
Wellbutrin, Zyban
Positive: Methamphetamines(MET)
Butabarbital
Butsol, Soneryl
Positive: Barbiturates(BAR)
Butalbital
Fioricet, Fiorinal
Positive: Barbiturates(BAR)
Canestan
Canestan ear/skin/etc
Non-reactive
Carbamazepine
Tegretol, Teril, Timonil
Non-reactive
Cephalexin
Ceporex, Keflex
Non-reactive
Chloral Hydrate
Welldorm
Non-reactive
Positive: Benzodiazepines(BZO) Potential
Chlordiazepoxide
reactants: Oxaprozin (Daypro), Sertraline
Bactrigras, Cordysol, Chlorohex, CX Powder,
Dermol, Hibicet, Hibiscrub, Hibisol, Hibitane,
Chlorhexidine Gluconate
Non-reactive
Instillagel, Neseptin, Nystaform, Serotulle,
Steripod, Tisept, Unisept, Uriflex, Uro-Trainer
Chloroquine
Positive: Methamphetamines(MET)
Chlorpheniramine Maleate
Galpseud, Haymine, Piriton
Non-reactive
Chlorpromazine
Thorazine, Largactil
Positive: Methamphetamines(MET)
Cimetidine
Dyspamet, Tagamet, Zita
Non-reactive
Citalopram
Cipramil
Non-reactive
Positive: Benzodiazepines(BZO) Potential
Clobazam
reactants: Oxaprozin (Daypro), Sertraline
Positive: Benzodiazepines(BZO) Potential
Clonazepam
Clonopin, Klonopin, Rivotril
reactants: Oxaprozin (Daypro), Sertraline
Positive: Benzodiazepines(BZO) Potential
Clorazepate
Tranxene
reactants: Oxaprozin (Daypro), Sertraline
Co-Amoxiclav
Augmentin, Augmentin Duo
Non-reactive
Positive: Cocaine(COC)
Codafen Continus, Codeine Linctus, Pediatric
Positive: Opiates(OPI, MOP, MOR)
Codeine/Codeine Phosphate
BP, Galcodine, Kapake, Migraleve, Solpadol,
Potential reactants: Dihydrocodeine
and/or Oxycodone(OXY)
Co-Phenotrope (Atropine/Diphenoxylate)
Magnapen
Non-reactive
d/l_Octopamine
Non-reactive
Positive: Benzodiazepines(BZO) Potential
Delorazepam
Briantum
reactants: Oxaprozin (Daypro), Sertraline
Deoxyephedrine
Methedrine
Positive: Methamphetamines(MET)
Positive: Methamphetamines(MET)
Desipramine
Norpramine, Pertrofane
Positive: Tricyclic-Antidepressants(TCA)
Decadron, Dexa-Rhinaspray Duo, Maxidex,
Dexamethasone
Non-reactive
Maxidol, Minims, Otomize, Sofradex
Dextroamphetamine
Adderall, Adderall XR, Dexedrine
Positive: Amphetamines(AMP)
Dextromethorphan
Dextromethorphan
Positive: Phencyclidine(PCP)
Generic Name of Compound
Trade Name of Compound
Dextropropoxyphene
Darvon, Darvocet, Co-proximal
Positive: Propoxyphene(PPX)
Positive: Benzodiazepines(BZO) Potential
Diazepam
Diazemuls, Stesolid, Valclair, Valium
reactants: Oxaprozin (Daypro), Sertraline
Dicloflex, Diclomax, Motifene, Volraman,
Diclofenac Sodium
Non-reactive
Volsaid, Voltarol
Dicyclomine
Kolanticon, Merbentyl
Non-reactive
Dihydrocodeine
DHC Continuous, Paramol, Remedeine,
Positive: Opiates(OPI, MOP, MOR)
Dimethicone
Asilone, Fancorsil
Non-reactive
Dipenoxylate with Atropine
Non-reactive
Diphenhydramine
Benadryl, Medinex, Nytol, Panadol Night
Non-reactive
Positive: Methamphetamines(MET)
d-Methamphetamine HCL Desoxyn, Methedrine, Methamprex
Potential reactants: Ephedrine,
l-Methamphetamine HCL
Vick's Inhaler
Pseudoephedrine, Phenylopropanolamine,
Phentermine, Phenmetrazine, Ranitidine
Dothiepin
Prothiaden
Non-reactive
Sinequan, Xepin
Positive: Tricyclic Antidepressants(TCA)
Doxycycline
Vibramycin, Vibramycin-D
Non-reactive
Dronabinol
Positive: Marijuana(THC)
Ecgonine
Positive: Cocaine(COC)
Efavirenz
Positive: Marijuana(THC)
Ephedrine
Ephedra & Ma Huang
Positive: Methamphetamines(MET)
Erythromycin
Arpimycin, Benzymycin, Erycane, Erymax,
Non-reactive
Esomeprazole
Positive: Marijuana(THC)
Positive: Benzodiazepines(BZO) Potential
Estazolam
reactants: Oxaprozin (Daypro), Sertraline
Ethambutold
Myambutol
Non-reactive
Positive: Opiates(OPI, MOP, MOR)
Ethylmorphine
Potential reactants, Dihydrocodeine
Fenfluramine
Fen Phen, Pendimin
Positive: Methamphetamines(MET)
Flucloxacillin
Co-fluampicil, Floxapen, Magnapen
Non-reactive
Positive: Benzodiazepines(BZO) Potential
Flunitrazepam
Rohypnol
reactants: Oxaprozin (Daypro), Sertraline
Fluoroquinolones
Positive: Opiates(OPI, MOP, MOR)
Fluoxetine
Prozac, Sarafem
Non-reactive
Flupentixol Decanoate
Depixol, Fluanox
Non-reactive
Fusidic Acid (Sodium Fusidate)
Fucithalmic, Fucibet, Fucidin
Non-reactive
Gentamicin Sulphate
Cidomycin, Genticin, Gentisone
Non-reactive
Hemp Seed Oil
Cannabis Seed
Positive: Marijuana(THC)
Positive: Opiates(OPI, MOP, MOR)
Hydrocodone
Lorcet, Loratab, Vicodin
Potential reactants: Dihydrocodeine
and/or Oxycodone(OXY)
Actinac, Alphaderm, Alphosyl-HC, Anugesic-
HC, Anusol-HC, Calmurid-HC, Canesten-HC,
Colioam, Daktacort, Dioderm, Econacort,
Efortelan, Efcortesel, Eurax-HC, Gergoderm,
Hydrocortisone
Non-reactive
Hydrocortistab, Hydrocortone,
Mildisonlipocream, Neo-cortef, Nystaform,
Perinal, Proctofoam, Quinocort, Terra-cortil,
Timodine, Uniroid-HC, Vioform-HC, Xyloproct
Hydrocortisone-17-butyrate
Locoid, Locoid C
Non-reactive
Positive: Opiates(OPI, MOP, MOR)
Hydromorphone
Dilaudid, Hydrostat
Potential reactants: Dihydrocodeine
and/or Oxycodone(OXY)
Generic Name of Compound
Trade Name of Compound
Hydroxychloroquine
Plaquenil
Non-reactive
Hydroxyzine Hydrochloride
Atarax, Ucerax
Non-reactive
Hyoscine butrylbromide
Busocopan, Scopoderm
Non-reactive
Brufen, Codafen, Fenbid, Ibugel, Ibuspray,
Ibuprofen
Non-reactive
Motrin, Proflex
Indomethacin
Flexin continus, Indocid, Indomod
Non-reactive
Interferon Alfa
Roferon-A, Intron A, Viraferon, Wellferon
Non-reactive
Isoniazide
Non-reactive
Angitak, Cedocard, Isocard, Isoket, Isordil,
Isosorbide Dinitrate
Non-reactive
Sorbichew, Sorbitrate, Sorbid SA
Ketoprofen
Orudis, Oruvail, Powergel
Non-reactive
Positive: Opiates(OPI, MOP, MOR)
Koalin and Morphine Mix
Dioclam, Entersan, Opazimes
Potential reactants: Dihydrocodeine
Labetalol
Trandate
Positive: Methamphetamines(MET)
Lactulose
Lactugal, Duphalec
Non-reactive
Lamotrigine
Lamitcal
Positive: Phencyclidine(PCP)
Lansoprazole
Heliclear, Zoton
Non-reactive
Levofloxacin
Levaquin
Positive: Opiates(OPI, MOP, MOR)
Lisinopril HCL
Carace, Zestril, Zestoretic
Non-reactive
Lofepramine
Gamanil, Lomont
Positive: Tricyclic Antidepressants(TCA)
Lofexidine
Britoflex
Non-reactive
Loperamide HCL
Immodium, Loperagen, Norimide
Non-reactive
Loratadine
Claritin
Non-reactive
Positive: Benzodiazepines(BZO) Potential
Lorazepam
reactants: Oxaprozin (Daypro), Sertraline
Positive: Benzodiazepines(BZO) Potential
Lormetazepam
Noctamide
reactants: Oxaprozin (Daypro), Sertraline
Magnesium Alginate
Gaviscon
Non-reactive
Manntiol
Gaviscon
Non-reactive
Anxitol, Lerisum, Medacepan, Nobritol,
Positive: Benzodiazepines(BZO) Potential
Medazepam
reactants: Oxaprozin (Daypro), Sertraline
Mefenamic Acid
Ponstan, Ponstel
Non-reactive
Meperidine
Demerol, Pethidine
Non-reactive
Positive: Methadone(MTD) Potential
Methadone Hydrochloride
Dolophine, Methadose, Physetone
reactants: Doxylamine
Positive: Ampthetamines(AMP) and/or
Ecstasy(MDMA); Potential reactants:
Methylenedioxyamphetamine
Eve (slang), Love Drug (slang)
Ephedrine, Pseudoephedrine,
Phenylopropanolamine, Phentermine,
Phenmetrazine, Ranitidine
Positive: Methamphetamines(MET)
and/or Ecstasy(MDMA); Potential
Methylenedioxymethamphetamine (MDMA) Ecstasy, XTC, Adam, E (all are slang)
reactants: Ephedrine, Pseudoephedrine,
Phenylopropanolamine, Phentermine,
Phenmetrazine, Ranitidine
Metoclopramide
Non-reactive
Anabact, Elyzol, Flagyl, Metrogel, Metrolyl,
Metronidazole
Metrotop, Neuratop, Noritate, Rozex, Zidoval, Non-reactive
Zymoet
Mexiletine
Positive: Methamphetamines(MET)
Astramorph, Cyclimorph, Duramorph, Morcap, Positive: Opiates(OPI, MOP, MOR)
Morhpine
Morphine Sulfate, MS Contin, Oramorph,
Potential reactants: Dihydrocodeine
Roxanol, Severedol
N-Acetyl Procainamide
Procainamide
Positive: Methamphetamines(MET)
Corgard, Corgaretic, Corgartic
Non-reactive
Generic Name of Compound
Trade Name of Compound
Naloxone
Non-reactive
Naltrexone
Antaxone, Nalorex, Trexan
Non-reactive
Aleve, Condrotec, Napratec, Naprosen,
Naproxen
Non-reactive
Naprosyn, Nycopren, Synflex
Nicoderm, Nicorette, Nicotinell, Nicotrol,
Nicotine
Positive: Cotinine(COT)
Niquitin
Nifedipine
Adalat, Nifecard, Nifar, Niften, Procardia
Non-reactive
Positive: Benzodiazepines(BZO) Potential
Nitrazepam
Mogadon, Somnite
reactants: Oxaprozin (Daypro), Sertraline
Nordiazepam
Nordaz, Stilny, Calmday, Madar, Vegesar
Positive: Benzodiazepines(BZO)
BiNovum, Brevinor, Climagest, Climesse,
Elleste Duet, Etracombi, Evorel, Kliofem,
Norethindrone
Kliovance, Loestrin, Micronor, Norlutin,
Non-reactive
Noriday, Normin, Norinyl, Noristat, Nuvelle,
Ovysmen, TriNovum, Trisquens, Utovian
Noscapine
Narcotine
Non-reactive
Ofloxacin
Positive: Opiates(OPI, MOP, MOR)
Olanzapine
Non-reactive
Omeprazole
Prilosec
Positive: Marijuana(THC)
Orphenadrine
Norflex, Norgesic, Disipil
Non-reactive
Oxaprozin
Positive: Benzodiazepines(BZO)
Positive: Benzodiazepines(BZO) Potential
Oxazepam
Serax, Ox-pam
reactants: Oxaprozin (Daypro), Sertraline
Oxycodone
Oxycontin, Percodan, Roxicet
Positive: Oxycodone(OXY)
Oxymetazoline
Afrin, Neo-synephrine
Non-reactive
Oxymorphone
Positive: Oxycodone(OXY)
Oxytetracycline
Terra-Cortil, Terramycin, Trimovate
Non-reactive
Pantoprazole
Protonix, Pantoloc
Positive: Marijuana(THC)
Papaverine
Positive: Opiates(OPI, MOP, MOR)
Paracetamol (Acetaminophen)
Fortagesic, Paratode
Non-reactive
Paracetamol (Acetaminophen)/Codeine
Tylenol 3, Co-codamol, Codafen, Co-dydramol, Positive: Opiates(OPI, MOP, MOR)
Preparations
Kapake, Remedine, Solpadol, Tylex
Potential reactants: Dihydrocodeine
Paroxetine
Paxil, Seroxat
Non-reactive
Penicillin
Combicillin, Mefoxin
Non-reactive
Pentobarbital
Nembutal
Positive: Barbiturates(BAR)
Amplan, Aolept, Apamin, Iryakin, Nemactil,
Pericyazine
Non-reactive
Neulactil, Propetyl, Psycholept
Positive: Phencyclidine(PCP) Potential
Phencyclidine
reactants: Thioridazine, Chlorpromazine,
Doxylamine, Lamotrignine
Phenlephrine
Neo-senephrine
Positive: Methamphetamines(MET)
Phenobarbital
Donnatal
Positive: Barbiturates(BAR)
Phenobarbitone (Phenobarbital)
Positive: Barbiturates(BAR)
Phentremine
Adipex, Obenix, Oby-Trim
Positive: Amphetamines(AMP)
Phenytoin
Dilantin, Epanutin, Epitard
Positive: Barbiturates(BAR)
Positive: Opiates(OPI, MOP, MOR)
Pholcodine
Galenphol, Strong BP, Pavacol-D, Thebacon
Potential reactants: Dihydrocodeine
Piperacillin
Pipracil, Tazobactam
Non-reactive
Poppy Seeds
Positive: Opiates(OPI, MOP, MOR)
Positive: Benzodiazepines(BZO) Potential
Prazepam
Centrax, Demetrin
reactants: Oxaprozin (Daypro), Sertraline
Delta-cortef, Econopred, Inflamase,
Prednisolone
Non-reactive
Pediapred, Prelone
Generic Name of Compound
Trade Name of Compound
Primidone
Mysoline
Positive: Barbiturates(BAR)
Novocain
Positive: Opiates(OPI, MOP, MOR)
Progesterol
Non-reactive
Allerfen, Anergan, Antinaus, Aprobit,
Promethazine
Avomine, Baymethzing, Diprozin, Fenergan,
Positive: Tricyclic Antidepressants(TCA)
Methazine, Phenergen
Propranolol
Beta-Progane, Inderal, Inderetic, Inderex
Non-reactive
Pseudoephedrine
Afrinol, Sudafed, Tylenol Cold (combination)
Positive: Amphetamines(AMP)
Quinacrine
Atacrine, Mepacrine
Positive: Methamphetamines(MET)
Ranitidine
Pylorid, Zantac
Positive: Methamphetamines(MET)
Rifampicin/Rifampin
Rimactine, Rifodin, Rofact
Positive: Opiates(OPI, MOP, MOR)
Aerocrom, Aerolin, Airomir, Asmasal,
Salbutamol
Combivent, Duovent, Ventide, Ventodisks,
Non-reactive
Ventolin, Volmax
Secobarbital
Positive: Barbiturates(BAR)
Selegiline
Selegiline
Positive: Methamphetamines(MET)
Sennosides
Non-reactive
Sertraline
Positive: Benzodiazepines(BZO)
Sodium Valporate
Depakene, Depakote, Epilim
Non-reactive
Positive: Benzodiazepines(BZO) Potential
Temazepam
Restoril
reactants: Oxaprozin (Daypro), Sertraline
Andropatch, Restandol, Sustanon, Virormone,
Testosterone
Non-reactive
Anabolic Steroids (slang)
Thioridazine Hydrochloride
Mellaril
Non-reactive
Thyroxine Sodium
Eltroxin
Non-reactive
Tramadol
Ultram, Tramake, Zamadol, Zydol
Positive: Tramadol(TML)
Trazodone (Molipaxin)
Desyrel, Molipaxin, Oleptro, Trialodine
Non-reactive
Positive: Benzodiazepines(BZO) Potential
Triazolam
reactants: Oxaprozin (Daypro), Sertraline
Tyramine
Tyramine
Positive: Methamphetamines(MET)
Venlafaxine
Effexor, Effexor XL
Positive: Phencyclidine(PCP)
Warfarin Sodium
Coumadin, Marevan
Non-reactive
Please note that this chart is not necessarily all inclusive. Also, drugs listed here may not always cross react. This guide is intended to be a "Quick Reference," not an authority. The intent of this chart is to show what "might" cause a positive, not necessarily what always will. Lab confirmation is recommended.

Source: http://www.spearesmedical.com/content/drug%20info/Cross%20Reaction%20Guide.pdf