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Material safety data sheet

3 October 2012
SAFETY DATA SHEET
Section 1: IDENTIFICATION of CHEMICAL PRODUCT and COMPANY
Product Name:
Maxalac LC Intramammary Antibiotic

Product Code:

Recommended Use:

An intramammary infusion to treat mastitis in lactating cows.
Company Identification:


Address:


Customer Centre:


National Poisons Information Centre:

Emergency Telephone Number:
Section 2: HAZARDS IDENTIFICATION

GHS Hazard Classifications:
Respiratory Sensitizer Category 1
Skin Sensitizer Category 1


GHS Pictograms:

Health hazard
Exclamation mark

Signal Word*:


Hazard Statements*:
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statements*:
Prevention
Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. In case of inadequate ventilation wear respiratory protection. Response
P302+P352
IF ON SKIN: Wash with plenty of soap and water. IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. If skin irritation or rash occurs: Get medical advice. If experiencing respiratory symptoms: Call a POISON CENTER or doctor. Wash contaminated clothing before reuse. Disposal
P501
Dispose of contents / container in accordance with local / national regulations. * N.B.: These statements are determined by Work Health and Safety regulations and may not reflect Signal Headings and First Aid and Safety statements on product labelling, which are determined by a competent authority during assessment for registration. Section 3: COMPOSITION / INFORMATION on INGREDIENTS
INGREDIENT
Section 4: FIRST AID MEASURES

First Aid Measures:
Consult the National Poisons Centre on 131126 or a doctor immediately in every case of suspected chemical poisoning. Never give fluids or induce vomiting if a patient is unconscious or convulsing regardless of cause of injury. If medical advice/attention is needed, have product container or label at hand.
Inhalation:
Sensitive individuals may exhibit allergic reactions, possibly life-threatening. If suspected, remove patient to fresh air. Lay patient down and keep warm and rested. If breathing is shallow or has stopped, ensure airway is clear and apply resuscitation. If breathing is difficult, give oxygen. Seek medical assistance immediately.
Ingestion:
Sensitive individuals may exhibit allergic reactions, possibly life-threatening. If swallowed, DO NOT induce vomiting. Rinse mouth. Keep subject warm and at rest. Seek medical advice, or contact the National Poisons Centre on 131126. May cause skin rashes in sensitised persons. If skin contact occurs, wash affected area thoroughly with plenty of soap and water for at least 20 minutes. If skin irritation or rash occurs, get medical advice/attention. Remove and wash / dispose of contaminated clothing promptly. If eye contact occurs, rinse cautiously with water for at least 20 minutes. Remove contact lenses, if present and easy to do. If eye irritation persists, get medical advice.
Advice to Doctor:
Treat as an overdose of, or sensitivity to, cephalosporin antibiotics. Section 5: FIRE FIGHTING MEASURES

Flash Point:

Hazardous Combustion
If involved in a fire, may emit toxic and corrosive fumes.
Products:

Extinguishing Media:

There is no restriction on the type of extinguisher which may be used. Use extinguishing media suitable for surrounding area.
Protective Equipment:
Gas-tight chemical resistant suit, protective gloves and boots and breathing apparatus
HAZCHEM Code:
Section 6: ACCIDENTAL RELEASE MEASURES

Spills and Disposal:
Wipe up spill with absorbent material and place in sealed labelled containers. Due to the nature of the packaging, large spills are unlikely to occur. In the event of a large spill, wear appropriate protective clothing. Exclude non-essential people from the area. Contain spill and sweep up / absorb with inert material such as soil, sand or absorbent granules and place in a sealable waste container. Ventilate area and wash spill site after pick-up complete. Dispose of waste safely in an approved landfill or refer to the relevant Land Waste Management Authority.
Protective Clothing:
For appropriate personal protective equipment see section 8.
Environmental
Prevent from entering drains, waterways or sewers. If contamination of drains and waterways Precautions:
Section 7: HANDLING AND STORAGE

Handling:
This is a Schedule 4 (Prescription Animal Remedy) product, available only to or through a veterinarian. Handle this product with care to avoid exposure, taking all recommended precautions. Avoid contact with skin and eyes. Wash hands after use. Use other personal protective equipment as required.
Storage:
Keep out of reach of children. Store below 30ºC (room temperature) in a dry place. Protect from light. Store away from foodstuffs.
Other Information:
Always read the label before use. See label for further information on handling and storage. Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION

This SDS describes personal protective measures relating to long term industrial and manufacturing
exposure and emergency situations, such as accidents and spills. See product label for personal
protective measures during normal use of the marketed product.

Exposure Limits:
No exposure limits have been assigned for this product. Do not handle until all safety precautions have been read and understood.
Protective Equipment:
Safety glasses with eye side shields or chemical goggles. Chemical protective gloves, e.g. PVC. Safety footwear or safety gumboots, e.g. rubber.
Engineering Controls:

Hygiene Precautions:
Do not drink, eat or smoke when handling this product. Wash hands after use. Section 9: PHYSICAL AND CHEMICAL PROPERTIES

Appearance:
Vapour Pressure:
Vapour density:
Odour threshold:
Relative density:
Specific Gravity:
Melting Point:
Solubility in Water:
Boiling Point:
Partition coefficient:
Flash Point:
Auto-ignition
temperature:
Evaporation Rate:
Decomposition
Flammability:
temperature:
Upper flammability
Viscosity:
Lower flammability
limits:

Section 10: STABILITY AND REACTIVITY

Stability:

When stored appropriately this product should show no significant degradation within the Expiry period shown on the label.
Hazardous
Polymerisation:

Materials to Avoid:
Section 11: TOXICOLOGICAL INFORMATION

Inhalation:
REMARK: Cefuroxime sodium is a cephalosporin and the most important adverse reaction is hypersensitivity.
Ingestion:
REMARK: Cefuroxime sodium is a cephalosporin and the most important adverse reaction is hypersensitivity. Cefuroxime causes gastrointestinal discomfort. REMARK: Cefuroxime sodium is a cephalosporin and the most important adverse reaction is hypersensitivity. REMARK: Cefuroxime sodium is a cephalosporin and the most important adverse reaction is hypersensitivity.
Chronic Effects:
Allergic reactions, possibly serious in sensitized individuals.
Mutagenicity:
Not considered to be mutagenic, based on the results of animal studies.
Carcinogenicity:
Not considered to be carcinogenic, based on the results of animal studies.
Reproductive Toxicity:
Not known to have effects on reproduction. Prolonged use may cause skin rashes and contact dermatitis.
Aspiration hazard:
REMARK: Cefuroxime sodium is a cephalosporin and the most important adverse reaction is hypersensitivity. Section 12: ECOLOGICAL INFORMATION

Ecotoxicity:
Ingredient
Persistence:
Persistence:
Bioaccumulation
Mobility
Water/Soil
Section 13: DISPOSAL INFORMATION

Product Disposal:
Dispose of product only by using according to label or by approved waste collection.
Container Disposal:
Section 14: TRANSPORT INFORMATION

Dangerous Goods
Not classified as a Dangerous Good according to the criteria of the Australian Dangerous Classification:

HAZCHEM Code:
Section 15: REGULATORY INFORMATION

Poisons Schedule:

APVMA Registration Nos:
Section 16: OTHER INFORMATION

This information is based on data believed by Jurox Pty Limited to be accurate at the time of writing but is subject to change without notice. It is given
in good faith, but no warranty expressed or implied is made as to its accuracy, completeness otherwise and no assumption of liability from howsoever
arising is made by Jurox Pty Limited by reason of the provision of this information. Every person dealing with the materials referred to herein does so
at his/her own risk absolutely and must make independent determinations of suitability and completeness of information from all sources to ensure
their proper use.

This SDS supercedes the version created on 2 March 2009 and updates the format as per the Code of Practice on
Preparation of Safety Data Sheets for Hazardous Chemicals, December 2011, published by Safe Work Australia.


CAS No
. means a unique number assigned to a chemical by the Chemical Abstracts Service.
GHS
means the ‘Globally Harmonized System of Classification and Label ing of Chemicals, 3rd Revised Edition’,
published by the United Nations.
LD50 means the median lethal dose, being a statistically derived single dose of a substance that can be expected to cause
death in 50% of animals.
PVC means Polyvinyl chloride.
STOT means Specific Target Organ Toxicity.
References
Atanasković-Marković M, Velicković TC, Gavrović-Jankulović M, Vucković O, Nestorović B. (2005). Immediate allergic reactions to cephalosporins and penicillins and their cross-reactivity in children. Pediatr Allergy Immunol., 16(4):341-7. Berkovitch M, Segal-Socher I, Greenberg R, Bulkowshtein M, Arnon J, Merlob P, Or-Noy A. (2000). First trimester exposure to cefuroxime: a prospective cohort study. Br J Clin Pharmacol. 50(2):161-5. Capel-Edwards K, Atkinson RM, Pratt DA. (1979). Toxicological studies on cefuroxime sodium. Toxicology. 13(1):1-5. END OF SDS

Source: http://www.jurox.com/downloads/product-material/MAXALAC_LC_INTRAMAMMARY_AUST.pdf

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