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CALCIUM MAGNESIUM
many years, this condition can lead to the development of osteoporosis, a disease characterized by brittle and weak WITH VITAMIN D3
bones, which increases the risk of hip and vertebrae fractures as well as spinal deformities and loss of height. Osteoporosis generally strikes both men and women in later life, though it is a particular concern for post- NATURAL HEALTH PRODUCTS
menopausal women. The risk of osteoporosis increases DIRECTORATE (NHPD) CLAIMS:
when the diet does not provide adequate calcium. Regular calcium supplementation along with weight-bearing Jamieson Calcium Magnesium with Vitamin D
exercises can help prevent bone resorption and approved for the following NHPD claims:
osteoporosis to reduce the risk of fractures later in life.1,2 • Calcium, magnesium and Vitamin D help in the New scientific evidence shows that calcium plays many development and maintenance of bones and teeth other important roles in the body. This mineral has been • Vitamin D helps in the absorption and use of calcium shown to support the health of the gastrointestinal tract by reducing the irritating effects of bile acids and fatty acids • Magnesium helps to maintain proper muscle function, helps in tissue formation, and helps the body to A recent study published in The Archives of Internal metabolize carbohydrates, fats and proteins Medicine showed that a sufficient intake of calcium from • Helps to prevent magnesium deficiency at three caplets both food and supplements may ward off certain types of cancer. Conducted by researchers from the National • Calcium intake, when combined with sufficient vitamin Cancer Institute in the United States, this study followed D, a healthy diet, and regular exercise, may reduce the almost 500,000 men and women between the ages of 50 to 71 for a total of seven years. At study completion, researchers found that women with higher calcium intakes GENERAL INFORMATION
(up to 1,300 mg/day), had a decreased risk of cancer Calcium is a major mineral in the body that is perhaps overall. They also showed that both men and women with most well known for its role in the formation and higher calcium intakes had a lower risk of developing maintenance of strong, healthy bones and tooth enamel. cancers of the digestive system (including head, neck, Although the majority of calcium in the body is found esophagus, stomach, bladder, colon and rectum), and in stored in the bones and teeth, a small amount is also found particular, colorectal cancer. The results were the same in the bloodstream. Calcium in the blood has many whether the calcium came from dairy products and other important roles to play: it transports nutrients across cell membranes; produces hormones and enzymes involved in Calcium is also thought to play a role in helping to reduce digestion and metabolism; is involved in nerve cell high blood pressure. By allowing the muscles to contract communication; promotes blood clotting and wound and relax, adequate calcium ensures that the heart and healing; and assists with muscle contractions. Calcium is an essential nutrient throughout the lifespan, but it is particularly important for growing children and adolescents Other research indicates that calcium can help relieve to help establish adequate bone mass for maintaining symptoms of pre-menstrual syndrome (PMS). Symptoms of PMS include irritability and mood swings. These symptoms have been attributed to several factors, one of Although only a small amount of calcium is found in the which is hormonal imbalances caused by insufficient bloodstream, the body keeps blood levels of calcium calcium. Regularly taking a calcium supplement may tightly regulated. If there is inadequate calcium in the prevent symptoms of PMS, and reduce the severity of bloodstream, bone resorption (breakdown) will occur in order to draw calcium from the bones into the blood. Over For Accidental Overdose (such as child ingesting formula)
Dial 911, 0 for operator assistance or call your nearest Poison Control Centre. For Professional Use Only
The information contained here has been accumulated from many sources. Indications are not intended as cures, they are simply a guideline to be used at your professional discretion. For more information please visit www.jamiesonvitamins.com or call 1-800-265-5088 to speak to a Consumer Affairs representative. Approximately half of the magnesium in the body is found What makes Calcium Magnesium with Vitamin D3 from in the bones and it is an essential nutrient to keep them Jamieson Laboratories different…and why does that strong and healthy. Magnesium also plays an important role in maintaining the function of nerves and regulating muscle relaxation. A deficiency in magnesium is 1) Magnesium and calcium work together to enhance associated with the occurrence of muscle spasms, tremors each other’s absorption and utilization.9,10 A 2:1 ratio and convulsion.6 Low magnesium levels have also been of calcium to magnesium ensures maximal calcium associated with psychiatric problems such as depression absorption and prevents any adverse gastrointestinal side effects that can occur when these two minerals Vitamin D is a fat soluble vitamin that regulates calcium and magnesium metabolism in the body. Vitamin D 2) It is formulated using a highly absorbable natural promotes intestinal absorption of calcium, mobilization of complex of five magnesium sources including oxide, calcium from bone stores, and retention of calcium by the citrate, fumarate, malate, and succinate. kidneys. It is therefore essential for the calcification of bones and teeth. New research has also found Vitamin D a more bioavailable form of vitamin D, and helps to inversely associated with the incidence of upper respiratory 4) Our premium formulations are manufactured using the Calcium, magnesium, and vitamin D work together in the 360 Pure process – a minimum of 360 quality tests body to enhance each other’s overall absorption and that guarantee traceability and reliability of raw utilization. Vitamin D increases the absorption of calcium. material, product safety, full potency and absolute Calcium and magnesium are essential factors in the formation and maintenance of healthy bones, but they also play an important role in the contraction and relaxation of INGREDIENT INFORMATION
muscles, including the heart. When calcium flows into the muscle tissue cells they contract. When calcium leaves, magnesium replaces it and the muscle relaxes. They also work together to normalize the muscle tone of blood Elemental Calcium…………………………………333 mg (From a complex of carbonate, citrate, fumarate, malate, Jamieson Calcium Magnesium with Vitamin D3 now Magnesium…………………………….………….167 mg contains increased vitamin D3 (200 IU). Also known as (From a complex of oxide, citrate, fumarate, malate, “the sunshine vitamin”, vitamin D helps calcium absorption, and promotes healthy bones, skin and teeth. Calcium intake, when combined with sufficient vitamin D, 3 (Cholecalciferol).………….5 mcg / 200 IU a healthy diet, and regular exercise, may reduce the risk of EXCIPIENTS
developing osteoporosis.1,2 Magnesium helps to maintain proper muscle function, helps in tissue formation, and Cellulose, vegetable stearic acid, vegetable magnesium helps the body to metabolize carbohydrates, fats and stearate, water soluble cellulose, titanium dioxide, proteins. It also helps to prevent magnesium deficiency at Brazilian palm tree wax, polysorbate 80, mineral oil, maltodextrin, purified magnesium silicate, citric acid, soy polysaccharides, triethyl citrate, crospovidone. Jamieson Calcium Magnesium with Vitamin D3 is formulated from natural sources and is pharmaceutically tested to guarantee full potency and absolute clinical For Accidental Overdose (such as child ingesting formula)
Dial 911, 0 for operator assistance or call your nearest Poison Control Centre. For Professional Use Only
The information contained here has been accumulated from many sources. Indications are not intended as cures, they are simply a guideline to be used at your professional discretion. For more information please visit www.jamiesonvitamins.com or call 1-800-265-5088 to speak to a Consumer Affairs representative. DIRECTIONS
Supportive Interactions
Vitamin D enhances calcium absorption. Garlic Adults - Take 1-3 caplets daily with meals. Take a few supplements along with calcium may help reduce high hours before or after taking other medication. Store between 15ºC-25ºC, away from children. WARNINGS AND PRECAUTIONS
INDICATED BENEFITS
• Maintains strong bones and healthy teeth1,2 • Helps prevent osteoporosis to reduce the risk of TOXICITY, ADVERSE REACTIONS, AND
SIDE EFFECTS
• May help reduce high blood pressure 4 • Plays a role in relieving symptoms of PMS 5 Calcium carbonate may cause symptoms of gas, bloating, or constipation. If this occurs, supplement with calcium Good for adolescents and post-menopausal women Aids function of nerves and muscles, including Excess calcium can contribute to the development of kidneys stones, and may cause calcium deposits in the If you experience abdominal pain, appetite loss, diarrhea, NUTRIENT INTERACTIONS
irregular heartbeat, mood or mental changes, nausea, extreme fatigue, weakness, or vomiting, discontinue use Drug Interactions
Calcium, vitamin D, and/or magnesium can interfere with tetracycline antibiotics, anticoagulants, and calcium REFERENCES
channel blockers. Consult your physician before use if you are taking any thiazide diuretics, as these can cause 1. Patrick L. Comparative absorption of calcium sources extremely high (potentially toxic) levels of calcium in the and calcium citrate malate for the prevention of body. Magnesium can increase levels of diuretics in the osteoporosis. Alternative Medicine Review. 1999; 4(2): 2. Shils ME, Olson JA, Shike M, Ross AC, editors. Nutrient Depletions
Modern Nutrition in Health and Disease, 10th edition. Excess calcium can impair the absorption of the mineral Philadelphia (PA): Lippincott Williams and Wilkins; Calcium, vitamin D, and/or magnesium may interact with 3. Park Y, Leitzmann M, Subar A, Hollenbeck A, or be depleted by corticosteroids, bronchodilators, anti- Schatzkin A. Dairy Food, Calcium and Risk of osteoporotics, cholesterol-reducing medications, anti-gout Cancer in the NIH-AARP Diet and Health Study. medications, anti-fungals, immunosuppressants, anti- Archives of Internal Medicine, 2009; 169 (4):391-401 malarial drugs, anti-tuberculosis drugs, histamine H2 blockers, oral contraceptives, biguanides, sulfonylureas, 4. Matsuura H. Calcium intake and cardiovascular diseases. Clinical Calcium. 2006; 16(1):25-30 Foods high in phosphorus (animal protein and soft drinks) 5. Thys-Jacobs S, Starkey P, Bernstein D, Tian J. promote urinary loss of calcium. High consumption of Calcium carbonate and the premenstrual syndrome: caffeine, and excess dietary fat and fibre can inhibit effects on premenstrual and menstrual symptoms. Am J Obstet Gynecol. 1998; 179(2):444-52. For Accidental Overdose (such as child ingesting formula)
Dial 911, 0 for operator assistance or call your nearest Poison Control Centre. For Professional Use Only
The information contained here has been accumulated from many sources. Indications are not intended as cures, they are simply a guideline to be used at your professional discretion. For more information please visit www.jamiesonvitamins.com or call 1-800-265-5088 to speak to a Consumer Affairs representative. 6. Eby GA, Eby KL. Rapid recovery from major depression using magnesium treatment. Med Hypotheses. 2006; 67(2): 362-70. Epub 2006 Mar 20. 7. Ginde A, Mansbach J, Camargo C. Association Between Serum 25-Hydroxyvitamin D Level and Upper Respiratory Tract Infection in the Third National Health and Nutrition Examination Survey. Archives of Internal Medicine. 2009; 169 (4):384-390. 8. Resnick LM. Cellular calcium and magnesium metabolism in the pathophysiology and treatment of hypertension and related metabolic disorders. Am J Med. 1992; 93 (2A): 11S-20S. 9. Briscoe, A.M. and Ragen, C. Relation of magnesium on calcium metabolism in man. Am J Clin Nutr. 1966; 19: 296-306. 10. DuRuisseau, J.P. and Marineau, J.M. Osteoporose medication calcique et magnesienne. See Int’l Sympos on Magnesium. 1971/1973; 223-226. 11. Seaman D. Health Care For Our Bones: A Practical Nutritional Approach to Preventing Osteoporosis Journal of Manipulative and Physiological Therapeutics. 2004; 27(9): 591-595 12. Shi H, Diriennzo D, Zemel B.Michael. Effects of dietary calcium on adipocyte lipid metabolism and body weight regulation in energy-restricted aP2- agoutitransgenic mice. The FASEB Journal. 2001; 15: 291-293. For Accidental Overdose (such as child ingesting formula)
Dial 911, 0 for operator assistance or call your nearest Poison Control Centre. For Professional Use Only
The information contained here has been accumulated from many sources. Indications are not intended as cures, they are simply a guideline to be used at your professional discretion. For more information please visit www.jamiesonvitamins.com or call 1-800-265-5088 to speak to a Consumer Affairs representative.

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JAMIE L. SHELLER SHELLER, P.C. 1528 Walnut Street, Fourth Floor Philadelphia, PA 19102 (215) 790-7300 EDUCATION: Villanova University School of Law Villanova, PAJ.D., May 1989 Contributing writer to “The Docket”New York UniversityNew York, NYB.A. with a double major in political science and communications,January 1986GPA 3.6 Cum LaudeVice-President of Undergraduate Dormitor

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