Microsoft word - 2375 - calcium magnesium with vitamin d.doc
CALCIUM MAGNESIUM
many years, this condition can lead to the development of osteoporosis, a disease characterized by brittle and weak
WITH VITAMIN D3
bones, which increases the risk of hip and vertebrae
fractures as well as spinal deformities and loss of height.
Osteoporosis generally strikes both men and women in
later life, though it is a particular concern for post-
NATURAL HEALTH PRODUCTS
menopausal women. The risk of osteoporosis increases
DIRECTORATE (NHPD) CLAIMS:
when the diet does not provide adequate calcium. Regular
calcium supplementation along with weight-bearing
Jamieson Calcium Magnesium with Vitamin D
exercises can help prevent bone resorption and
approved for the following NHPD claims:
osteoporosis to reduce the risk of fractures later in life.1,2
• Calcium, magnesium and Vitamin D help in the
New scientific evidence shows that calcium plays many
development and maintenance of bones and teeth
other important roles in the body. This mineral has been
• Vitamin D helps in the absorption and use of calcium
shown to support the health of the gastrointestinal tract by
reducing the irritating effects of bile acids and fatty acids
• Magnesium helps to maintain proper muscle function,
helps in tissue formation, and helps the body to
A recent study published in The Archives of Internal
metabolize carbohydrates, fats and proteins
Medicine showed that a sufficient intake of calcium from
• Helps to prevent magnesium deficiency at three caplets
both food and supplements may ward off certain types of
cancer. Conducted by researchers from the National
• Calcium intake, when combined with sufficient vitamin
Cancer Institute in the United States, this study followed
D, a healthy diet, and regular exercise, may reduce the
almost 500,000 men and women between the ages of 50 to
71 for a total of seven years. At study completion,
researchers found that women with higher calcium intakes
GENERAL INFORMATION
(up to 1,300 mg/day), had a decreased risk of cancer
Calcium is a major mineral in the body that is perhaps
overall. They also showed that both men and women with
most well known for its role in the formation and
higher calcium intakes had a lower risk of developing
maintenance of strong, healthy bones and tooth enamel.
cancers of the digestive system (including head, neck,
Although the majority of calcium in the body is found
esophagus, stomach, bladder, colon and rectum), and in
stored in the bones and teeth, a small amount is also found
particular, colorectal cancer. The results were the same
in the bloodstream. Calcium in the blood has many
whether the calcium came from dairy products and other
important roles to play: it transports nutrients across cell
membranes; produces hormones and enzymes involved in
Calcium is also thought to play a role in helping to reduce
digestion and metabolism; is involved in nerve cell
high blood pressure. By allowing the muscles to contract
communication; promotes blood clotting and wound
and relax, adequate calcium ensures that the heart and
healing; and assists with muscle contractions. Calcium is
an essential nutrient throughout the lifespan, but it is
particularly important for growing children and adolescents
Other research indicates that calcium can help relieve
to help establish adequate bone mass for maintaining
symptoms of pre-menstrual syndrome (PMS). Symptoms
of PMS include irritability and mood swings. These
symptoms have been attributed to several factors, one of
Although only a small amount of calcium is found in the
which is hormonal imbalances caused by insufficient
bloodstream, the body keeps blood levels of calcium
calcium. Regularly taking a calcium supplement may
tightly regulated. If there is inadequate calcium in the
prevent symptoms of PMS, and reduce the severity of
bloodstream, bone resorption (breakdown) will occur in
order to draw calcium from the bones into the blood. Over
For Accidental Overdose (such as child ingesting formula)
Dial 911, 0 for operator assistance or call your nearest Poison Control Centre.
For Professional Use Only
The information contained here has been accumulated from many sources.
Indications are not intended as cures, they are simply a guideline to be used at your professional discretion.
For more information please visit www.jamiesonvitamins.com or call 1-800-265-5088 to speak to a Consumer Affairs representative.
Approximately half of the magnesium in the body is found
What makes Calcium Magnesium with Vitamin D3 from
in the bones and it is an essential nutrient to keep them
Jamieson Laboratories different…and why does that
strong and healthy. Magnesium also plays an important
role in maintaining the function of nerves and regulating
muscle relaxation. A deficiency in magnesium is
1) Magnesium and calcium work together to enhance
associated with the occurrence of muscle spasms, tremors
each other’s absorption and utilization.9,10 A 2:1 ratio
and convulsion.6 Low magnesium levels have also been
of calcium to magnesium ensures maximal calcium
associated with psychiatric problems such as depression
absorption and prevents any adverse gastrointestinal
side effects that can occur when these two minerals
Vitamin D is a fat soluble vitamin that regulates calcium
and magnesium metabolism in the body. Vitamin D
2) It is formulated using a highly absorbable natural
promotes intestinal absorption of calcium, mobilization of
complex of five magnesium sources including oxide,
calcium from bone stores, and retention of calcium by the
citrate, fumarate, malate, and succinate.
kidneys. It is therefore essential for the calcification of
bones and teeth. New research has also found Vitamin D
a more bioavailable form of vitamin D, and helps to
inversely associated with the incidence of upper respiratory
4) Our premium formulations are manufactured using the
Calcium, magnesium, and vitamin D work together in the
360 Pure process – a minimum of 360 quality tests
body to enhance each other’s overall absorption and
that guarantee traceability and reliability of raw
utilization. Vitamin D increases the absorption of calcium.
material, product safety, full potency and absolute
Calcium and magnesium are essential factors in the
formation and maintenance of healthy bones, but they also
play an important role in the contraction and relaxation of
INGREDIENT INFORMATION
muscles, including the heart. When calcium flows into the
muscle tissue cells they contract. When calcium leaves,
magnesium replaces it and the muscle relaxes. They also
work together to normalize the muscle tone of blood
Elemental Calcium…………………………………333 mg
(From a complex of carbonate, citrate, fumarate, malate,
Jamieson Calcium Magnesium with Vitamin D3 now
Magnesium…………………………….………….167 mg
contains increased vitamin D3 (200 IU). Also known as
(From a complex of oxide, citrate, fumarate, malate,
“the sunshine vitamin”, vitamin D helps calcium
absorption, and promotes healthy bones, skin and teeth.
Calcium intake, when combined with sufficient vitamin D,
3 (Cholecalciferol).………….5 mcg / 200 IU
a healthy diet, and regular exercise, may reduce the risk of
EXCIPIENTS
developing osteoporosis.1,2 Magnesium helps to maintain
proper muscle function, helps in tissue formation, and
Cellulose, vegetable stearic acid, vegetable magnesium
helps the body to metabolize carbohydrates, fats and
stearate, water soluble cellulose, titanium dioxide,
proteins. It also helps to prevent magnesium deficiency at
Brazilian palm tree wax, polysorbate 80, mineral oil,
maltodextrin, purified magnesium silicate, citric acid, soy
polysaccharides, triethyl citrate, crospovidone.
Jamieson Calcium Magnesium with Vitamin D3 is
formulated from natural sources and is pharmaceutically
tested to guarantee full potency and absolute clinical
For Accidental Overdose (such as child ingesting formula)
Dial 911, 0 for operator assistance or call your nearest Poison Control Centre.
For Professional Use Only
The information contained here has been accumulated from many sources.
Indications are not intended as cures, they are simply a guideline to be used at your professional discretion.
For more information please visit www.jamiesonvitamins.com or call 1-800-265-5088 to speak to a Consumer Affairs representative.
DIRECTIONS Supportive Interactions
Vitamin D enhances calcium absorption. Garlic
Adults - Take 1-3 caplets daily with meals. Take a few
supplements along with calcium may help reduce high
hours before or after taking other medication. Store
between 15ºC-25ºC, away from children.
WARNINGS AND PRECAUTIONS INDICATED BENEFITS
• Maintains strong bones and healthy teeth1,2
• Helps prevent osteoporosis to reduce the risk of
TOXICITY, ADVERSE REACTIONS, AND SIDE EFFECTS
• May help reduce high blood pressure 4
• Plays a role in relieving symptoms of PMS 5
Calcium carbonate may cause symptoms of gas, bloating,
or constipation. If this occurs, supplement with calcium
Good for adolescents and post-menopausal women
Aids function of nerves and muscles, including
Excess calcium can contribute to the development of
kidneys stones, and may cause calcium deposits in the
If you experience abdominal pain, appetite loss, diarrhea,
NUTRIENT INTERACTIONS
irregular heartbeat, mood or mental changes, nausea,
extreme fatigue, weakness, or vomiting, discontinue use
Drug Interactions
Calcium, vitamin D, and/or magnesium can interfere with
tetracycline antibiotics, anticoagulants, and calcium
REFERENCES
channel blockers. Consult your physician before use if you
are taking any thiazide diuretics, as these can cause
1. Patrick L. Comparative absorption of calcium sources
extremely high (potentially toxic) levels of calcium in the
and calcium citrate malate for the prevention of
body. Magnesium can increase levels of diuretics in the
osteoporosis. Alternative Medicine Review. 1999; 4(2):
2. Shils ME, Olson JA, Shike M, Ross AC, editors.
Nutrient Depletions
Modern Nutrition in Health and Disease, 10th edition.
Excess calcium can impair the absorption of the mineral
Philadelphia (PA): Lippincott Williams and Wilkins;
Calcium, vitamin D, and/or magnesium may interact with
3. Park Y, Leitzmann M, Subar A, Hollenbeck A,
or be depleted by corticosteroids, bronchodilators, anti-
Schatzkin A. Dairy Food, Calcium and Risk of
osteoporotics, cholesterol-reducing medications, anti-gout
Cancer in the NIH-AARP Diet and Health Study.
medications, anti-fungals, immunosuppressants, anti-
Archives of Internal Medicine, 2009; 169 (4):391-401
malarial drugs, anti-tuberculosis drugs, histamine H2
blockers, oral contraceptives, biguanides, sulfonylureas,
4. Matsuura H. Calcium intake and cardiovascular
diseases. Clinical Calcium. 2006; 16(1):25-30
Foods high in phosphorus (animal protein and soft drinks)
5. Thys-Jacobs S, Starkey P, Bernstein D, Tian J.
promote urinary loss of calcium. High consumption of
Calcium carbonate and the premenstrual syndrome:
caffeine, and excess dietary fat and fibre can inhibit
effects on premenstrual and menstrual symptoms. Am J Obstet Gynecol. 1998; 179(2):444-52.
For Accidental Overdose (such as child ingesting formula)
Dial 911, 0 for operator assistance or call your nearest Poison Control Centre.
For Professional Use Only
The information contained here has been accumulated from many sources.
Indications are not intended as cures, they are simply a guideline to be used at your professional discretion.
For more information please visit www.jamiesonvitamins.com or call 1-800-265-5088 to speak to a Consumer Affairs representative.
6. Eby GA, Eby KL. Rapid recovery from major depression using magnesium treatment. Med Hypotheses. 2006; 67(2): 362-70. Epub 2006 Mar 20. 7. Ginde A, Mansbach J, Camargo C. Association Between Serum 25-Hydroxyvitamin D Level and
Upper Respiratory Tract Infection in the Third National Health and Nutrition Examination Survey. Archives of Internal Medicine. 2009; 169 (4):384-390.
8. Resnick LM. Cellular calcium and magnesium
metabolism in the pathophysiology and treatment of hypertension and related metabolic disorders. Am J Med. 1992; 93 (2A): 11S-20S.
9. Briscoe, A.M. and Ragen, C. Relation of magnesium
on calcium metabolism in man. Am J Clin Nutr. 1966; 19: 296-306.
10. DuRuisseau, J.P. and Marineau, J.M. Osteoporose medication calcique et magnesienne. See Int’l Sympos on Magnesium. 1971/1973; 223-226.
11. Seaman D. Health Care For Our Bones: A Practical
Nutritional Approach to Preventing Osteoporosis Journal of Manipulative and Physiological Therapeutics. 2004; 27(9): 591-595
12. Shi H, Diriennzo D, Zemel B.Michael. Effects of dietary calcium on adipocyte lipid metabolism and body weight regulation in energy-restricted aP2- agoutitransgenic mice. The FASEB Journal. 2001; 15: 291-293.
For Accidental Overdose (such as child ingesting formula)
Dial 911, 0 for operator assistance or call your nearest Poison Control Centre.
For Professional Use Only
The information contained here has been accumulated from many sources.
Indications are not intended as cures, they are simply a guideline to be used at your professional discretion.
For more information please visit www.jamiesonvitamins.com or call 1-800-265-5088 to speak to a Consumer Affairs representative.
DSC Notice: 40/2001 Data Standards: Supporting revised Cessation of Smoking Monitoring Requirements Implementation Date: Immediate DATA SET CHANGE CONTROL PROCEDURE This paper gives notification of changes to be included in the NHS Data Dictionary & Manual and the NHS CDS Manual as appropriate. These will be consolidated into the publications in due course. Sum
JAMIE L. SHELLER SHELLER, P.C. 1528 Walnut Street, Fourth Floor Philadelphia, PA 19102 (215) 790-7300 EDUCATION: Villanova University School of Law Villanova, PAJ.D., May 1989 Contributing writer to “The Docket”New York UniversityNew York, NYB.A. with a double major in political science and communications,January 1986GPA 3.6 Cum LaudeVice-President of Undergraduate Dormitor