Name: Maria Amália da Silva Jurado Position: Assistant Professor in the Biochemistry Department of the Faculty of Science and Technology of the University of Coimbra, since1992. Email adress: asjurado@ci.uc.pt Research area: Biomembranes (with emphasis on the role of the lipid-bilayer component in health and disease conditions) and Biochemical Toxicology (toxicity studies relying on in vitro approaches, using model and native membranes, prokaryotic and eukaryotic cells in culture, protoplasts and mitochondria). Education: PhD in Biochemistry by the Faculty of Science and Technology of the University of Coimbra, in May 1992. Master D in Cellular Biology, by the Zoology Department of the Faculty of Science and Technology of the University of Coimbra, in January 1986. Biology Degree (scientific area) by the Faculty of Science and Technology of the University of Coimbra, in July 1980. Previous positions: Teaching Assistant of Biology in the Zoology Department of the Faculty of Science and Technology of the University of Coimbra,1980-1992. Research activities: Head of the Membrane Toxicity Group of the CNC. The main purposes of this research group are:
a) to identify alterations of the physical properties of the lipid-bilayer membrane
component related with cell malfunctioning and disease;
b) to investigate membrane adaptation mechanisms of microorganisms to
environmental stress, and to explore the ability of chemical compounds or altered living conditions to restore normal membrane functions, by modulation of lipid bilayer properties;
c) to characterize membrane mediated toxic effects of drugs (cytostatics, anti-
arrhythmics) and environmental pollutants (insecticides, herbicides, organometals) using different biological systems, from dispersions of synthetic and native membrane lipids, to subcellular fractions (biological membranes and mitochondria), protoplasts and prokaryotic and eukaryotic cells in culture.
Teaching activities: Biomembranes (Biochemistry Degree- 3d year) Biophysical and Biochemical Toxicology (Biochemistry Degree- 4th year) Bioenergetics and Biomembranes (Biomedical Engineering Degree – 3d year) Biokinetics and Bioenergetics (Master Degree in Cell Biology)
Lipids and Membranes (Master Degree in Medicament Technologies) Selected publications:
J. D. Martins, A. S. Jurado, A. J. M. Moreno and V. M. C. Madeira (2005). Comparative study of tributyltin toxicity on two bacteria of the genus Bacillus. Toxicology in Vitro, 19: 943-949. J. P. Monteiro, A. S. Jurado, A. J. M. Moreno and V. M. C. Madeira (2005). Toxicity of methoprene as assessed by the use of a model microorganism. Toxicology in Vitro,19: 951-956. Maria A. S. Fernandes, Amália S. Jurado, Romeu A. Videira, Maria S. Santos, António J. M. Moreno, Astrida Velena, Gunars Duburs, Catarina R. Oliveira and Joaquim A. F. Vicente (2005). Cerebrocast promotes the cotransport of H+ and Cl- in rat liver mitochondria. Mitochondrion, 5: 341-351. Sónia M. L. J. Rosa, Maria do Carmo Antunes-Madeira, Manuel J. Matos, Amália S. Jurado and Vítor M. C. Madeira (2000). Lipid composition and dynamics of cell membranes of Bacillus stearothermophilus adapted to amiodarone. Biochim. Biophys. Acta, 1487: 286-295. Paula C. Luxo, Amália S. Jurado and Vítor M.C. Madeira (1998). Lipid composition changes induced by tamoxifen in a bacterial model system. Biochim. Biophis. Acta 1369:71-84. Maria Manuel Donato, Amália S. Jurado, Maria do Carmo Antunes-Madeira and Vítor M. C. Madeira (1997). Comparative study of the toxic actions of DDT and DDE on the growth and respiratory activity of a microorganism used as a model. Appl. Environ. Microbiol., 63: 4948-4951. Amália S. Jurado, Leonor M. Almeida and Vítor M. C. Madeira (1991). Fluidity of bacterial membrane lipids monitored by intramolecular excimerization of 1,3-di(2- pyrenyl)propane. Biochem. Biophys. Res. Commun., 176: 356-363. Amália S. Jurado, Teresa J. T. Pinheiro and Vítor M. C. Madeira (1991). Physical studies on membrane lipids of Bacillus stearothermophilus. Temperature and calcium effects. Arch. Biochem. Biophys., 289:167-179.
Scientific Reference Guide Depression in Adults What are the best treatments? Description of Condition Depression is a common medical condition with a lifetime prevalence in the United States of 15% among adults. Symptoms include feelings of sadness, hopelessness, or guilt; diminished interest or pleasure in usual activities; decreased ability to think or concentrate; and disruptions in sl
The role of the bronchial provocation challenge tests in the diagnosis of exercise-induced bronchoconstriction in elite swimmers A Castricum, K Holzer, P Brukner, et al. 2010 44: 736-740 originally published online October 23, Br J Sports Med 2008doi: 10.1136/bjsm.2008.051169Updated information and services can be found at: http://bjsm.bmj.com/content/44/10/736.full.html References
