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: Maria Amália da Silva Jurado Position
: Assistant Professor in the Biochemistry Department of the Faculty of Science
and Technology of the University of Coimbra, since1992. Email adress
: email@example.com Research area:
Biomembranes (with emphasis on the role of the lipid-bilayer
component in health and disease conditions) and Biochemical Toxicology (toxicity
studies relying on in vitro
approaches, using model and native membranes, prokaryotic
and eukaryotic cells in culture, protoplasts and mitochondria). Education:
PhD in Biochemistry by the Faculty of Science and Technology of the University of
Coimbra, in May 1992.
Master D in Cellular Biology, by the Zoology Department of the Faculty of Science and
Technology of the University of Coimbra, in January 1986.
Biology Degree (scientific area) by the Faculty of Science and Technology of the
University of Coimbra, in July 1980. Previous positions
Teaching Assistant of Biology in the Zoology Department of the Faculty of Science and
Technology of the University of Coimbra,1980-1992. Research activities:
Head of the Membrane Toxicity Group of the CNC.
The main purposes of this research group are:
a) to identify alterations of the physical properties of the lipid-bilayer membrane
component related with cell malfunctioning and disease;
b) to investigate membrane adaptation mechanisms of microorganisms to
environmental stress, and to explore the ability of chemical compounds or altered living conditions to restore normal membrane functions, by modulation of lipid bilayer properties;
c) to characterize membrane mediated toxic effects of drugs (cytostatics, anti-
arrhythmics) and environmental pollutants (insecticides, herbicides, organometals) using different biological systems, from dispersions of synthetic and native membrane lipids, to subcellular fractions (biological membranes and mitochondria), protoplasts and prokaryotic and eukaryotic cells in culture.
Biomembranes (Biochemistry Degree- 3d year)
Biophysical and Biochemical Toxicology (Biochemistry Degree- 4th year)
Bioenergetics and Biomembranes (Biomedical Engineering Degree – 3d year)
Biokinetics and Bioenergetics (Master Degree in Cell Biology)
Lipids and Membranes (Master Degree in Medicament Technologies) Selected publications:
J. D. Martins, A. S. Jurado, A. J. M. Moreno and V. M. C. Madeira (2005).
Comparative study of tributyltin toxicity on two bacteria of the genus Bacillus.
Toxicology in Vitro, 19
J. P. Monteiro, A. S. Jurado, A. J. M. Moreno and V. M. C. Madeira (2005). Toxicity of
methoprene as assessed by the use of a model microorganism. Toxicology in Vitro, 19
Maria A. S. Fernandes, Amália S. Jurado, Romeu A. Videira, Maria S. Santos, António J.
M. Moreno, Astrida Velena, Gunars Duburs, Catarina R. Oliveira and Joaquim A. F.
Vicente (2005). Cerebrocast promotes the cotransport of H+ and Cl- in rat liver
mitochondria. Mitochondrion, 5
Sónia M. L. J. Rosa, Maria do Carmo Antunes-Madeira, Manuel J. Matos, Amália S.
Jurado and Vítor M. C. Madeira (2000). Lipid composition and dynamics of cell
membranes of Bacillus stearothermophilus
adapted to amiodarone. Biochim.
Biophys. Acta, 1487:
Paula C. Luxo, Amália S. Jurado and Vítor M.C. Madeira (1998). Lipid composition
changes induced by tamoxifen in a bacterial model system. Biochim. Biophis. Acta 1369
Maria Manuel Donato, Amália S. Jurado, Maria do Carmo Antunes-Madeira and Vítor
M. C. Madeira (1997). Comparative study of the toxic actions of DDT and DDE on
the growth and respiratory activity of a microorganism used as a model. Appl.
Environ. Microbiol., 63:
Amália S. Jurado, Leonor M. Almeida and Vítor M. C. Madeira (1991). Fluidity of
bacterial membrane lipids monitored by intramolecular excimerization of 1,3-di(2-
pyrenyl)propane. Biochem. Biophys. Res. Commun., 176
Amália S. Jurado, Teresa J. T. Pinheiro and Vítor M. C. Madeira (1991). Physical
studies on membrane lipids of Bacillus stearothermophilus
. Temperature and calcium
effects. Arch. Biochem. Biophys., 289
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