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SUBSTITUTES APPENDIX A OF THE OMAC 1999
OLYMPIC MOVEMENT ANTI-DOPING CODE
PROHIBITED CLASSES OF SUBSTANCES AND PROHIBITED METHODS
1 January 2001
PROHIBITED CLASSES OF SUBSTANCES
Prohibited substances in class (A) include the following examples:
amineptine, amiphenazole, amphetamines, bromantan, caffeine*,
carphedon, cocaine, ephedrines**,fencamfamin, formoterol ***,
mesocarb, pentetrazol, pipradrol, salbutamol***, salmeterol***,
. and related substances
* For caffeine the definition of a positive is a concentration in urine greater than
12 micrograms per millilitre. ** For cathine, the definition of a positive is a concentration in urine greater than 5 micrograms per millilitre. For ephedrine and methylephedrine, the definition of a positive is a concentration in urine greater than 10 micrograms per millilitre. For phenylpropanolamine and pseudoephedrine, the definition of a positive is a concentration in urine greater than 25 micrograms per millilitre. *** Permitted by inhaler only to prevent and/or treat asthma and exercise-induced asthma. Written notification by a respiratory or team physician that the athlete has asthma and/or exercise-induced asthma, is necessary to the relevant medical authority prior to competition. At the Olympics Games, athletes who request permission to inhale a permitted beta agonist will be assessed by an independent medical panel.
NOTE: All imidazole preparations are acceptable for topical use. Vasoconstrictors may
be administered with local anaesthetic agents. Topical preparations (e.g. nasal,
ophthalmological, rectal) of adrenaline and phenylephrine are permitted. B. Narcotics
Prohibited substances in class (B) include the following examples:
buprenorphine, dextromoramide, diamorphine (heroin), methadone,
morphine, pentazocine, pethidine
. and related substances
NOTE: codeine, dextromethorphan, dextropropoxyphene, dihydrocodeine,
diphenoxylate, ethylmorphine, pholcodine, propoxyphene and tramadol are permitted. C. Anabolic agents
Prohibited substances in class (C) include the following examples:
1. Anabolic androgenic steroids a.
clostebol, fluoxymesterone, metandienone, metenolone,
19-norandrostenediol, 19-norandrostenedione, oxandrolone,
. and related substances.
androstenediol, androstenedione, dehydroepiandrosterone (DHEA),
dihydrotestosterone, testosterone*, . and related substances
Evidence obtained from metabolic profiles and/or isotopic ratio measurements may be
* The presence of a testosterone (T) to epitestostrone (E) ratio greater than six (6) to
one (1) in the urine of a competitor constitutes an offence unless there is evidence that this ratio is due to a physiological or pathological condition, e.g. low epitestosterone excretion, androgen producing tumour, enzyme deficiencies.
In the case of T/E greater than 6, it is mandatory that the relevant medical authority
conducts an investigation before the sample is declared positive. A full report will be written
and will include a review of previous tests, subsequent tests and any results of endocrine
investigations. In the event that previous tests are not available, the athlete should be tested
unannounced at least once per month for three months. The results of these investigations
should be included in the report. Failure to co-operate in the investigations will result in
declaring the sample positive.
2. Beta-2 agonists
bambuterol, clenbuterol, fenoterol, formoterol*, reproterol, salbutamol*,
. and related substances
*Authorized by inhalation as described in Article (I.A.).
For salbutamol the definition of a positive under the anabolic agent category is a concentration
in urine greater than 1000 nanograms per millilitre. D. Diuretics
Prohibited substances in class (D) include the following examples:
acetazolamide, bumetanide, chlortalidone, etacrynic acid, furosemide,
hydrochlorothiazide, mannitol*, mersalyl, spironolactone, triamterene,
. and related substances.
E. Peptide hormones, mimetics and analogues
Prohibited substances in class (E) include the following examples and their analogues and
1. Chorionic Gonadotrophin
(hCG) prohibited in males only;
2. Pituitary and synthetic gonadotrophins
(LH) prohibited in males only;
4. Growth hormone
5. Insulin-like Growth Factor
and all the respective releasing factors and their analogues;
permitted only to treat athletes with certified insulin-dependent diabetes. Written
certification of insulin-dependent diabetes must be obtained from an endocrinologist or team
The presence of an abnormal concentration of an endogenous hormone in class (E)or
its diagnostic marker(s) in the urine of a competitor constitutes an offence unless it has been proven to be due to a physiological or pathological condition.
The following procedures are prohibited: 1. Blood doping : means the administration of blood, red blood cells and/or related
blood products to an athlete, which may be preceded by withdrawal of blood from the athlete, who continues to train in such a blood-depleted state.
2 Administering artificial oxygen carriers or plasma expanders;
3. Pharmacological, chemical and physical manipulation.
CLASSES OF PROHIBITED SUBSTANCES IN CERTAIN
Where the rules of a responsible authority so provide, tests will be conducted for ethanol. B. Cannabinoids
Where the rules of a responsible authority so provide, tests will be conducted for
cannabinoids (e.g. Marijuana, Hashish). At the Olympic Games, tests will be conducted for
cannabinoids. A concentration in urine of 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic
acid (carboxy-THC) greater than 15 nanograms per millilitre constitutes doping. C. Local anaesthetics
Injectable local anaesthetics are permitted under the following conditions:
a. bupivacaine, lidocaine, mepivacaine, procaine, and related substances, can be used but not cocaine. Vasoconstrictor agents may be used in conjunction with local
b. only local or intra-articular injections may be administered; c. only when medically justified.
Where the rules of a responsible authority so provide, notification of administration may be
necessary. D. Glucocorticosteroids
The systemic use of glucocorticosteroids is prohibited when administered orally, rectally,
or by intravenous or intramuscular injection.
When medically necessary, local and intra-articular injections of glucocorticosteroids are
permitted. Where the rules of a responsible medical authority so provide, notification of
administration may be necessary. E. Beta-blockers
Prohibited substances in class (E) include the following examples:
acebutolol, alprenolol, atenolol, labetalol, metoprolol, nadolol, oxprenolol,
. and related substances
Where the rules of a responsible authority so provide, tests will be conducted for beta-blockers.
SUMMARY OF URINARY CONCENTRATIONS
ABOVE WHICH IOC ACCREDITED LABORATORIES
MUST REPORT FINDINGS FOR SPECIFIC SUBSTANCES
IV. OUT-OF-COMPETITION TESTING
Unless specifically requested by the responsible authority, out-of-competition testing is
directed solely at prohibited substances in class I.C. (Anabolic Agents), I.D. (Diuretics), I.E. (Peptide Hormones, Mimetics and Analogues), and II (Prohibited Methods).
LIST OF EXAMPLES OF PROHIBITED SUBSTANCES
AND PROHIBITED METHODS
CAUTION: This is not an exhaustive list of prohibited substances. Many substances that do not appear on this list are considered prohibited under the term "and related substances". Athletes must ensure that any medicine, supplement, over-the-counter preparation or any other substance they use does not contain any Prohibited Substance.
amineptine, amfepramone, amiphenazole, amphetamine, bambuterol,
bromantan, bupropion, caffeine, carphedon, cathine, cocaine,
cropropamide, crotethamide, ephedrine, etamivan, etilamphetamine,
etilefrine, fencamfamin, fenetylline, fenfluramine, formoterol, heptaminol,
mefenorex, mephentermine, mesocarb, methamphetamine,
methoxyphenamine, methylenedioxyamphetamine, methylephedrine,
methylphenidate, nikethamide, norfenfluramine,
parahydroxyamphetamine, pemoline, pentetrazol, phendimetrazine,
phentermine, phenylephrine, phenylpropanolamine, pholedrine, pipradrol,
prolintane, propylhexedrine, pseudoephedrine, reproterol, salbutamol,
salmeterol, selegiline, strychnine
buprenorphine, dextromoramide, diamorphine (heroin), hydrocodone,
methadone, morphine, pentazocine, pethidine,
androstenediol, androstenedione, bambuterol, boldenone, clenbuterol,
clostebol, danazol, dehydrochlormethyltestosterone,
dehydroepiandrosterone (DHEA), dihydrotestosterone, drostanolone,
fenoterol, fluoxymesterone, formebolone, formoterol, gestrinone,
mesterolone, metandienone, metenolone, methandriol, methyltestosterone,
mibolerone, nandrolone, 19-norandrostenediol, 19-norandrostenedione,
norethandrolone, oxandrolone, oxymesterone, oxymetholone, reproterol,
salbutamol, salmeterol, stanozolol, terbutaline, testosterone,
acetazolamide, bendroflumethiazide, bumetanide, canrenone,
chlortalidone, ethacrynic acid, furosemide, hydrochlorothiazide,
indapamide, mannitol (by intravenous injection), mersalyl,
bromantan, diuretics (see above), epitestosterone, probenecid
PEPTIDE HORMONES, MIMETICS AND ANALOGUES
ACTH, erythropoietin (EPO), hCG*, hGH
, insulin, LH*, clomiphene*,
cyclofenil*, tamoxifen*, aromatase inhibitors*
* prohibited in males only
acebutolol, alprenolol, atenolol, betaxolol, bisoprolol, bunolol, carteolol,
celiprolol, esmolol, labetalol, levobunolol, metipranolol, metoprolol,
nadolol, oxprenolol, pindolol, propranolol, sotalol, timolol.
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