PROGRAMME DAY 1 – Wednesday 16 February 2011 PHYSICOCHEMICAL CONSIDERATIONS IN DEVELOPING A DOSAGE
Professor Thomas Rades, Convenor, Formulation and Delivery of Bioactives Research Theme, University of Otago, Dunedin, NZ SESSION 1 Chairs – Dr Arlene McDowell & Mr Nicky Thomas Drug delivery systems for problem drugs – and they’re all problem drugs
Professor Thomas Rades, Convenor, Formulation and Delivery of Bioactives Research Theme, University of Otago, Dunedin, NZ Lipid drug delivery systems CRS Keynote Speaker: Assoc Prof Anette Müllertz Faculty of Pharmaceutical Sciences, University of Copenhagen Morning tea and poster viewing Solid lipid delivery systems
Dr Clare Strachan, School of Pharmacy, University of Otago, Dunedin, NZ Particulate lipid delivery systems Assoc. Prof. Ben Boyd, Pharmacy and Pharmaceutical Sciences, Monash Spider silk –a new biomaterial for pharmaceutical applications Dr Julia Myschik, Department of Pharmacy, Ludwig-Maximilians University, Lunch and poster viewing SESSION 2 Chairs – Dr Clare Strachan & Mr Pranav Karmwar Solubilisation of Brick Dust: Chemistry, Physics, and Processes Dr Sebastian Kolzenburg, BASF The Chemical Company, Germany SESSION 3 Chairs – Assoc. Prof. Natalie Medlicott & Mr Jasper Chiu ATA Scientific Guest Speaker – Dr Mark Pothecary (Malvern Instruments) Molecules to Nano Particles – Selecting the optimum characterisation technique *Students eligible for NZCRS speaker prize Counterfeit screening via Raman spectroscopy, PCA analysis and SIMCA classification: the Cialis example
*S. FRASER1, J. OUGHTON2, K. GORDON1, T. RADES3, C. STRACHAN3 1Department of Chemistry, University of Otago, Dunedin, NZ 2Medsafe, MOH, 3School of Pharmacy, University of Otago, Dunedin, NZPrediction of Native Protein Concentration using FTIR, Fluorescence and Multivariate Analysis
*Paulina GUZMAN1, Stefania BALDURDOTTIR2, Lene JORGENSEN2, Clare STRACHAN1, Thomas RADES1, Natalie MEDLICOTT1 1School of Pharmacy, University of Otago, Dunedin, NZ, 2Faculty of Pharmaceutical Science, University of Copenhagen, DK. Investigating the effect of different preparation methods on the dissolution behaviour of amorphous indomethacin samples *Pranav KARMWAR1, Kirsten GRAESER1, Keith C. GORDON2, Clare J.
STRACHAN1, Thomas RADES1 1School of Pharmacy, 2Department of Chemistry, University of Otago, Dunedin, Re-crystallization of indomethacin - polyvinylpyrrolidone solid dispersions prepared by ball milling during storage and dissolution
*P.A.PRIEMEL1, T. RADES1, H. GROHGANZ2, C. J. STRACHAN1 1School of Pharmacy, University of Otago, Dunedin, NZ, 2Faculty of Pharmaceutical Sciences, University of Copenhagen Preparation and characterization of the co-amorphous drug/drug combination between indomethacin and naproxen
*Korbinian LOEBMANN1, Clare STRACHAN1, Keith GORDON2, Holger GROHGANZ3, Thomas RADES1 1 School of Pharmacy, University of Otago, Dunedin, NZ, 2 Department of Chemistry, University of Otago, Dunedin, NZ, 3 Department of Pharmaceutics and Analytical Chemistry, The Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark Bus departs for Glenfalloch restaurant from outside Otago Museum Dinner at Glenfalloch restaurant Portobello Bus returns from Glenfalloch restaurant to Otago Museum DAY 2 – Thursday 17 February 2011 PATIENT CONSIDERATIONS IN DEVELOPING A DOSAGE FORM SESSION 4 Chairs – Prof Thomas Rades & Miss Sara Hanning Matching dosage form and drug delivery to clinical need Assoc. Prof. Natalie Medlicott, School of Pharmacy, University of Otago, Provision of Suitable Formulations for Children: A Greater Challenge than Licensing?
Assoc. Prof. David Reith, Women's and Children's Health, Paediatrics & Child Health, Dunedin School of Medicine, University of Otago, Dunedin, NZ Morning tea and poster viewing SESSION 5 Chairs – Dr Steve Kerr & Miss Katie Owens miRNAs powerful regulators of protein expression as molecular targets for drugs Dr Andrew Bahn, Department of Physiology, University of Otago, Dunedin, NZ Dosage form considerations for animal patients
Dr Arlene McDowell, School of Pharmacy, University of Otago, Dunedin, NZCharacterising immunological needs of patients Dr Roslyn Kemp, Microbiology and Immunology, University of Otago, Dunedin, SESSION 6 Chairs – Dr Roslyn Kemp & Miss Ice Kojarunchitt
Ì Students eligible for FDB poster prize Rapid fire Oral Poster Orals
1. The effect of moisture on Eudragit RLPO tablets
ÌChompak PIRAYAVARAPORN, Thomas RADES, Ian G. TUCKER School of Pharmacy, University of Otago, Dunedin, NZ
2. A study of milk thistle (Silybum marianum) quality using different extraction solvents
Piyanan ASSAWASUWANNAKIT, Clare STRACHAN and David SCHMIERER
School of Pharmacy, University of Otago, Dunedin, NZ
3. Liquid Chromatography–Mass Spectrometry (LC-MS) Analysis of Insulin Analogues for Pharmacokinetic Studies ÌEmma SALIS1, David REITH2, Natalie MEDLICOTT1 1School of Pharmacy, 2Dunedin School of Medicine, University of Otago, Dunedin, NZ
4. The effect of mechanical activation on the stability of nifedipine solid dispersions
ÌFang ZHANG, Fang TIAN, Marja SAVOLAINEN, Dorothy SAVILLE, Jukka RANTANEN,
Thomas RADES School of Pharmacy, University of Otago, Dunedin, NZ
5. Designing surface-decorated-polyarginine polymeric nanoparticles to improve oral bioavailability ÌJasper CHIU1, Ian TUCKER1, Doug ECKERY2, Bernie McLEOD3, Arlene McDOWELL1 1School of Pharmacy, University of Otago, Dunedin, NZ, 2School of Biological Sciences, Victoria University of Wellington, NZ, 3Agresearch, Invermay, NZ
6. The effect of surgery on the glucuronidation and sulphation of paracetamol
ÌKatie OWENS1, David REITH2, Natalie MEDLICOTT1, Mathew ZACHARIAS3, Sree CHARY1 1School of Pharmacy, 2Dunedin School of Medicine, 3Medical and Surgical Sciences, University of Lunch & NZCRS Annual Meeting SESSION 7 Chairs – Dr Bernie McLeod & Mrs Emma Salis *Students eligible for NZCRS speaker prize Identification of antioxidant constituents in Puha (Sonchusoleraceus L.) leaf extracts *Zongquan OU, David SCHMIERER, Thomas RADES and Arlene MCDOWELL School of Pharmacy, University of Otago, Dunedin, NZ Transcutaneous Immunisation by Lipid Col oidal Systems *Teerawan RATTANAPAK, Katie YOUNG, Thomas RADES, Sarah HOOK School of Pharmacy, University of Otago, Dunedin, NZ In vivo investigation of modified P407 gels containing cubosomes as vaccine delivery system
*T. KOJARUNCHITT1, S. BALDURSDOTTIR3, S. RIZWAN2, T. RADES1 and S. HOOK1 1School of Pharmacy, 2Department of Anatomy and Structural Biology, Otago School of Medical Sciences, University of Otago, Dunedin, NZ, 3Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark Monolayer Study of PIM Mimetics -Novel Immunomodulating Agents *Madlen HUBERT, Sarah HOOK, David LARSEN, Colin HAYMAN, Gavin
PAINTER, Phillip RENDLE, Thomas RADES School of Pharmacy, University of Otago, Dunedin, NZ Effect of formulation on the pharmacodynamics of the anaesthetic tribromoethanol in laboratory mice *Jessica FOTHERGILL, Arlene MCDOWELL, Natalie MEDLICOTT School of Pharmacy, University of Otago, Dunedin, NZ Determination of GYKI-52466 in rat plasma and brain by HPLC-DAD and its application to a pharmacokinetic study
*P.K. NAYAK1,2, D.S. KERR1, H. ZHANG2 1Dept of Pharmacology and Toxicology, University of Otago School of Medical Sciences, and 2School of Pharmacy, University of Otago, Dunedin, New Zealand Characterisation of supersaturated self-nanoemulsifying drug delivery systems (S-SNEDDS) during in vitro lipolysis Nicky THOMAS1, Anette MÜLLERTZ2, Thomas RADES1 1School of Pharmacy, University of Otago, Dunedin, NZ, and 2 Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark FDB poster prize and Closing
Professor Thomas Rades, Convenor, Formulation and Delivery of Bioactives Research ThemeNZCRS student prizes
Dr Arlene McDowell, Vice President of the New Zealand chapter of the Controlled Release Society
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